维生素D及其类似物在口腔黏膜病与牙周病治疗中的作用 : = The role of vitamin D and its analogues in the treatment of oral mucosal diseases and periodontal diseases

维生素D是体内必不可少的营养物质,近年来,维生素D在调节免疫和抗炎方面的作用受到越来越多的关注。但是,维生素D在体内应用可能产生高钙血症、高钙尿症等副作用。因此,通过分子改建得到的维生素D类似物可以保留与维生素D相似的调节作用,同时降低副作用。补充维生素D或应用维生素D类似物可能有助于免疫炎症性疾病的预防和治疗。现围绕维生素D及其类似物在口腔黏膜病与牙周病防治中的作用做一综述。文献复习结果表明,维生素D及其类似物对口腔黏膜屏障的完整性起到保护作用,阻止或延缓口腔扁平苔藓的发生,也可为预防及治疗牙周炎提供参考价值。.

Vitamin D is an essential nutrient in the body. In recent years, increasing attention has been paid to its role in regulating immunity and anti-inflammatory effects. However, the application of vitamin D in vivo may produce some side effects, such as hypercalcemia and hypercalciuria. Some analogs of vitamin D obtained through molecular modification can reduce the side effects while retaining a similar regulatory action as that of vitamin D. The supplementation of vitamin D or the use of vitamin D analogs may contribute to the prevention and treatment of immune inflammatory diseases. This article reviews the role of vitamin D and its analogues in the prevention and treatment of oral mucosal diseases and periodontal diseases. The literature review results show that vitamin D and its analogues can protect the integrity of the oral mucosal barrier, prevent or delay the occurrence of oral lichen planus, and provide a reference value for the prevention and treatment of periodontitis..

Medienart:

E-Artikel

Erscheinungsjahr:

2019-12-31 16:54

2019

Erschienen:

2019-12-31 16:54

Enthalten in:

Zur Gesamtaufnahme - year:2019

Enthalten in:

Kou qiang ji bing fang zhi - (2019), 12 vom: 31 16:54. Dez., Seite 804-808

Original Letters: Enthalten in 口腔疾病防治 (DE-600)2991569-7 (DE-600)2991569-7 广东省广州市

Reihe:

China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health

Sprache:

Chinesisch

Weiterer Titel:

The role of vitamin D and its analogues in the treatment of oral mucosal diseases and periodontal diseases

Beteiligte Personen:

吴倩 [VerfasserIn]
王健 [Sonstige Person]
牛丽 [Sonstige Person]
杨雪 [Sonstige Person]
唐晓琳 [Sonstige Person]

Links:

oversea.cnki.net [lizenzpflichtig]

Themen:

中国医科大学附属口腔医院牙周病科
免疫
医药、卫生
医药卫生科技
口腔内科学
口腔科学
炎症
类似物
维生素D
维生素D受体
钙磷代谢
高钙尿症
高钙血症
Analogues
Calcium and phosphorus metabolism
Hypercalcemia
Hypercalciuria
Immunity
Inflammation
Medicine & Public Health
Stomatology
Vitamin D
Vitamin D receptor

Anmerkungen:

Author info:WU Qian;WANG Jian;NIU Li;YANG Xue;TANG Xiaolin;Department of Periodontics, School of Stomatology,China Medical University

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

CAJ64610490X