婴幼儿反复喘息136例病因分析 : = Etiological analysis of recurrent wheezing in 136 infants

目的分析婴幼儿反复喘息的病因。方法收集患儿的一般资料、临床症状及体征、病原学、胸部CT等影像学、免疫学进行分析,研究反复喘息的病因。结果引起反复喘息的主要原因为:婴幼儿哮喘47例(34.6%)、感染62例(45.6%)、闭塞性细支气管炎4例(2.9%)、支气管肺发育不良7例(5.1%)、胃食管反流2例(1.5%),支气管内异物2例(1.5%),气道畸形9例(6.6%),心血管畸形2例(1.5%),免疫缺陷1例(0.7%)。感染相关喘息中有23例被检出合并现症感染,支原体感染达16.1%。哮喘预测指数(API)阳性者46例(34.6%)。106例胸部CT检查中90例为炎症改变,46例患儿支气管镜表现为气管支气管内膜炎为主。62例患儿考虑感染后喘息,但还应注意其他少见病因可能。结论婴幼儿反复喘息大部分有因可寻,感染相关喘息和哮喘是导致婴幼儿反复喘息的常见原因,诊断应从常见病入手,但还应注意少见病可能,加强随访评估。.

Objective To analyze the etiology of recurrent wheezing in infants.Methods The general information,clinical symptons and signs,etiology,chest CT and other imaging and immunology of the children were collected and analyzed to study the causes of recurrent wheezing.Results The main causes of recurrent wheezing were as follows: 47 infants with asthma(34.6%), 62 infants with infection(45.6%), 4 infants with bronchiolitis obliterans(2.9%), 7 infants with bronchopulmonary dysplasia(5.1%), 2 infants with gastroesophageal reflux(1.5%), 2 infants with intrabronchial foreign bodies(1.5%), 9 infants with airway malformation(6.6%), 2 infants with cardiovascular malformation(1.5%) and 1 case with immune deficiency(0.7%).Current infection was found in 23 cases of infection-related wheezing, with mycoplasma infection reaching 16.1%.Asthma predictive index(API) was positive in 46 cases(34.6%).Ninety cases demonstrated inflammation in the chest CT examination, while 46 cases showed endobronchitis under bronchoscopy.Post-infection wheezing was considered in 62 patients, while attention should be paid to the possibility of other rare causes.Conclusion The causes of recurrent wheezing infant can be found in most cases.Infection-related wheezing and asthma are common causes.Diagnosis should be started with common diseases,and the possibility of rare diseases cannot be ignored.Strengthened follow-up evaluation are needed..

Medienart:

E-Artikel

Erscheinungsjahr:

2019-12-15

2019

Erschienen:

2019-12-15

Enthalten in:

Zur Gesamtaufnahme - year:2019

Enthalten in:

Fu jian yi yao za zhi - (2019), 06 vom: 15. Dez., Seite 12-15

Original Letters: Enthalten in 福建医药杂志 (DE-600)2995191-4 (DE-600)2995191-4 福建省福州市

Reihe:

China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health

Sprache:

Chinesisch

Weiterer Titel:

Etiological analysis of recurrent wheezing in 136 infants

Beteiligte Personen:

陈琼华 [VerfasserIn]
郑敬阳 [Sonstige Person]
张圳杰 [Sonstige Person]
林印涛 [Sonstige Person]
曾丽娥 [Sonstige Person]
林春燕 [Sonstige Person]
张谭 [Sonstige Person]

Links:

oversea.cnki.net [lizenzpflichtig]

Themen:

儿科学
医药、卫生
医药卫生科技
喘息
婴幼儿
小儿内科学
病因
福建省泉州市儿童医院呼吸科
Etiology
Infant
Medicine & Public Health
Paediatrics
Wheezing

Anmerkungen:

Author info:CHEN Qionghua;ZHENG Jingyang;ZHANG Zhenjie;LIN Yintao;ZENG Li'e;LIN Chunyan;ZHANG Tan;Department of Respiratory, Quanzhou Children's Hospital

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

CAJ646100726