抗梅毒治疗和RPR滴度对梅毒孕妇妊娠结局的影响 : = Effect of Anti-syphilis Treatment and RPR Titer on Pregnancy Outcome in pregnant women with syphilis
目的对比不同抗梅毒治疗、不同RPR滴度对梅毒孕妇妊娠结局的影响。方法选择2016年5月—2018年3月中102例梅毒孕妇,接受规范治疗的患者40例视作1组,未接受规范治疗的32例视作2组,未接受治疗的30例视作3组,比较3组妊娠结局。结果 1组孕妇不良妊娠结局发生率为2.50%,2组为15.63%,3组为43.33%,1组、2组、3组新生儿不良结局发生率为5.00%、21.88%、50.00%,差异有统计学意义(P<0.05);RPR滴度≥1:8的孕妇,接受规范治疗后所产新生儿RPR滴度明显更低,差异有统计学意义(P<0.05);3组新生儿出生后不同时间RPR滴度转阴率,差异有统计学意义(P<0.05)。结论对梅毒孕妇开展规范化治疗有助于妊娠结局的明显改善,梅毒孕妇RPR滴度越高,新生儿先天性梅毒发生风险越高。.
Objective To compare the effects of different anti-syphilis treatments and different RPR titers on the pregnancy outcome of pregnant women with syphilis. Methods 102 pregnant women with syphilis were selected from May2016 to March 2018. 40 patients who received standard treatment were treated as group A, 32 patients who did not receive standard treatment were treated as group B, and 30 patients who did not receive treatment were treated as 30 patients. In the 3 groups, the pregnancy outcomes of the 3 groups were compared. Results The incidence of adverse pregnancy outcome was 2.50% in group A, 15.63% in group B, and 43.33% in group C. The incidence of adverse outcomes in neonates in group A, group B and group C was 5.00%, 21.88%, 50.00%,the difference was statistically significant P<0.05; pregnant women with RPR titer ≥1:8 had significantly lower RPR titers in the neonates after standard treatment,the difference was statistically significant(P<0.05); there were statistical differences in the RPR titer between the three groups at different times after birth, with significance, the difference was statistically significant(P<0.05). Conclusion Standardized treatment of pregnant women with syphilis is helpful for the improvement of pregnancy outcome. The higher the RPR titer of pregnant women with syphilis, the higher the risk of congenital syphilis in neonates..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019-11-05 2019 |
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| Erschienen: |
2019-11-05 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2019 |
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| Enthalten in: |
Xi tong yi xue - (2019), 21 vom: 05. Nov., Seite 64-66 Original Letters: Enthalten in 系统医学 (DE-600)2988797-5 (DE-600)2988797-5 北京市 : [Verlag nicht ermittelbar] |
| Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
Effect of Anti-syphilis Treatment and RPR Titer on Pregnancy Outcome in pregnant women with syphilis |
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| Beteiligte Personen: |
吕宣艳 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Anmerkungen: |
Author info:Lu Xuan-yan;Department of Outpatient, Xinyi City Center for Disease Control and Prevention |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CAJ645869643 |
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| 245 | 1 | 0 | |a 抗梅毒治疗和RPR滴度对梅毒孕妇妊娠结局的影响 |b = Effect of Anti-syphilis Treatment and RPR Titer on Pregnancy Outcome in pregnant women with syphilis |
| 246 | 3 | 1 | |a Effect of Anti-syphilis Treatment and RPR Titer on Pregnancy Outcome in pregnant women with syphilis |
| 264 | 1 | |c 2019-11-05 | |
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| 490 | 0 | |a China Academic Journals (CAJ) |a E |a 医药卫生科技 = Medicine & Public Health | |
| 500 | |a Author info:Lu Xuan-yan;Department of Outpatient, Xinyi City Center for Disease Control and Prevention | ||
| 520 | |a 目的对比不同抗梅毒治疗、不同RPR滴度对梅毒孕妇妊娠结局的影响。方法选择2016年5月—2018年3月中102例梅毒孕妇,接受规范治疗的患者40例视作1组,未接受规范治疗的32例视作2组,未接受治疗的30例视作3组,比较3组妊娠结局。结果 1组孕妇不良妊娠结局发生率为2.50%,2组为15.63%,3组为43.33%,1组、2组、3组新生儿不良结局发生率为5.00%、21.88%、50.00%,差异有统计学意义(P<0.05);RPR滴度≥1:8的孕妇,接受规范治疗后所产新生儿RPR滴度明显更低,差异有统计学意义(P<0.05);3组新生儿出生后不同时间RPR滴度转阴率,差异有统计学意义(P<0.05)。结论对梅毒孕妇开展规范化治疗有助于妊娠结局的明显改善,梅毒孕妇RPR滴度越高,新生儿先天性梅毒发生风险越高。 | ||
| 520 | |a Objective To compare the effects of different anti-syphilis treatments and different RPR titers on the pregnancy outcome of pregnant women with syphilis. Methods 102 pregnant women with syphilis were selected from May2016 to March 2018. 40 patients who received standard treatment were treated as group A, 32 patients who did not receive standard treatment were treated as group B, and 30 patients who did not receive treatment were treated as 30 patients. In the 3 groups, the pregnancy outcomes of the 3 groups were compared. Results The incidence of adverse pregnancy outcome was 2.50% in group A, 15.63% in group B, and 43.33% in group C. The incidence of adverse outcomes in neonates in group A, group B and group C was 5.00%, 21.88%, 50.00%,the difference was statistically significant P<0.05; pregnant women with RPR titer ≥1:8 had significantly lower RPR titers in the neonates after standard treatment,the difference was statistically significant(P<0.05); there were statistical differences in the RPR titer between the three groups at different times after birth, with significance, the difference was statistically significant(P<0.05). Conclusion Standardized treatment of pregnant women with syphilis is helpful for the improvement of pregnancy outcome. The higher the RPR titer of pregnant women with syphilis, the higher the risk of congenital syphilis in neonates. | ||
| 610 | 2 | 4 | |a 江苏省新沂市疾病预防控制中心门诊部 |
| 650 | 4 | |a 性病学 | |
| 650 | 4 | |a 皮肤病学与性病学 | |
| 650 | 4 | |a 医药、卫生 | |
| 650 | 4 | |a Infectious Disease | |
| 650 | 4 | |a Dermatosis and Venereal Disease | |
| 650 | 4 | |a 医药卫生科技 | |
| 650 | 4 | |a Medicine & Public Health | |
| 650 | 4 | |a 抗梅毒 | |
| 650 | 4 | |a 治疗 | |
| 650 | 4 | |a RPR滴度 | |
| 650 | 4 | |a 梅毒 | |
| 650 | 4 | |a 孕妇 | |
| 650 | 4 | |a Anti-syphilis | |
| 650 | 4 | |a Treatment | |
| 650 | 4 | |a RPR titer | |
| 650 | 4 | |a Syphilis | |
| 650 | 4 | |a Pregnant women | |
| 650 | 4 | |a Pregnancy outcome | |
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