高脂饮食对肠道功能的影响 : = The effect of high-fat diet on intestinal function
正常的肠道功能是机体健康的重要因素,而肠道功能异常则可引起一系列肠道疾病,包括炎症性肠病及肠道肿瘤。作为影响肠道功能的因素之一,高脂饮食带来的一系列病理生理效应也伴随着医疗科研的进步而受到人们的广泛关注。高脂饮食可能引起肠道菌群的组成发生变化,肠道屏障功能受损,进而引起肠道慢性低度炎性反应,肠道干细胞的异常增殖以及引发肿瘤性病变。鉴于高脂饮食的危害性,本文主要针对近年来高脂饮食对肠道炎症、肠道屏障功能和肠道干细胞的影响以及药物的作用的研究进展进行综述。.
Normal intestinal function is a critical factor of body health and abnormal intestinal function can cause a series of intestinal diseases, including inflammatory bowel disease and intestinal tumor. As one of the factors affecting bowel function, a series of pathophysiological effects brought by high-fat diet have been getting widely concerned with the progress of medical research. High-fat diet may have negative effect on the structure of gut microbiota and do harm to intestinal barrier function, which may lead to chronic low-grade inflammatory reactions in the intestine, abnormal proliferation of intestinal stem cells, and neoplastic lesions. In view of the harmfulness of high-fat diet, this paper mainly reviews the recent research progress on the effects of high-fat diet on intestinal inflammation, intestinal barrier function and intestinal stem cells, as well as the therapeutic effects of drugs..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019-12-15 2019 |
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| Erschienen: |
2019-12-15 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2019 |
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| Enthalten in: |
Sheng ming de hua xue - (2019), 06 vom: 15. Dez., Seite 1098-1106 Original Letters: Enthalten in 生命的化学 (DE-600)2993862-4 (DE-600)2993862-4 上海市 |
| Reihe: |
China Academic Journals (CAJ), A, 理工A(数学物理力学天地生) = Mathematics/ Physics/ Mechanics/ Astronomy China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
The effect of high-fat diet on intestinal function |
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| Beteiligte Personen: |
董娇娥 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Anmerkungen: |
Author info:DONG Jiao'e;LIU Jie;HU Xuan;XIONG Zhengguo;DUN Yaoyan;School of Medicine, Three Gorges University |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 0 | |a 高脂饮食对肠道功能的影响 |b = The effect of high-fat diet on intestinal function |
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| 500 | |a Author info:DONG Jiao'e;LIU Jie;HU Xuan;XIONG Zhengguo;DUN Yaoyan;School of Medicine, Three Gorges University | ||
| 520 | |a 正常的肠道功能是机体健康的重要因素,而肠道功能异常则可引起一系列肠道疾病,包括炎症性肠病及肠道肿瘤。作为影响肠道功能的因素之一,高脂饮食带来的一系列病理生理效应也伴随着医疗科研的进步而受到人们的广泛关注。高脂饮食可能引起肠道菌群的组成发生变化,肠道屏障功能受损,进而引起肠道慢性低度炎性反应,肠道干细胞的异常增殖以及引发肿瘤性病变。鉴于高脂饮食的危害性,本文主要针对近年来高脂饮食对肠道炎症、肠道屏障功能和肠道干细胞的影响以及药物的作用的研究进展进行综述。 | ||
| 520 | |a Normal intestinal function is a critical factor of body health and abnormal intestinal function can cause a series of intestinal diseases, including inflammatory bowel disease and intestinal tumor. As one of the factors affecting bowel function, a series of pathophysiological effects brought by high-fat diet have been getting widely concerned with the progress of medical research. High-fat diet may have negative effect on the structure of gut microbiota and do harm to intestinal barrier function, which may lead to chronic low-grade inflammatory reactions in the intestine, abnormal proliferation of intestinal stem cells, and neoplastic lesions. In view of the harmfulness of high-fat diet, this paper mainly reviews the recent research progress on the effects of high-fat diet on intestinal inflammation, intestinal barrier function and intestinal stem cells, as well as the therapeutic effects of drugs. | ||
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| 650 | 4 | |a 内分泌腺疾病及代谢病 | |
| 650 | 4 | |a 内科学 | |
| 650 | 4 | |a 医药、卫生 | |
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| 650 | 4 | |a 肠道屏障功能 | |
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| 650 | 4 | |a 药物的作用 | |
| 650 | 4 | |a high-fat diet | |
| 650 | 4 | |a intestinal inflammation | |
| 650 | 4 | |a intestinal barrier function | |
| 650 | 4 | |a intestinal stem cells | |
| 650 | 4 | |a drug effects | |
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