人体肺腺泡区多肺泡模型的建立和重力方向对颗粒物沉积影响的数值模拟研究 : = Multi-alveolar model and numerical simulation of influence of gravity direction on inhaled particle deposition in human pulmonary acinus region

目的针对现行人体肺腺泡模型与实际差异过大问题,建立更加符合实际的人体肺腺泡模型并采用该模型数值模拟研究重力方向对人体肺腺泡区颗粒物沉积的影响。方法采用Inventor 2016建立人体肺腺泡模型,采用fluent 15.0数值模拟重力方向的影响。结果建立的"柱状气管+球状肺泡"架构多肺泡模型各项数据与文献一致;重力方向对颗粒物在肺腺泡区总体沉积率影响不大,但会显著影响颗粒物沉积位置。结论建立的"柱状气管+球状肺泡"架构的多肺泡模型能满足不同研究对模型的需要,重力方向是影响颗粒物沉积的重要因素。.

Objective To establish a more realistic human lung acinar model that can be used to simulate the influence of gravity direction on the deposition of inhaled particles in the human pulmonary acinus region. Methods Inventor2016 was used to establish a human lung acinar model,and the influence of gravity direction was simulated by fluent 15.0.Results The data of the multi-alveolar model of the "columnar tracheal+spheroidal alveolar" structure was consistent with literature. The gravity direction had little effect on the total deposition fraction of inhaled particles in the human pulmonary acinus region,but it could significantly affect the location of particle deposition. Conclusion The multialveolar model of the "columnar tracheal + spheroidal alveolar" structure can meet the needs of different research for models. Gravity direction is an important factor that affects the deposition of particles..

Medienart:

E-Artikel

Erscheinungsjahr:

2019-06-25

2019

Erschienen:

2019-06-25

Enthalten in:

Zur Gesamtaufnahme - year:2019

Enthalten in:

Jun shi yi xue - (2019), 06 vom: 25. Juni, Seite 460-463

Original Letters: Enthalten in 军事医学 (DE-600)2992831-X (DE-600)2992831-X 北京市

Reihe:

China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health

China Academic Journals (CAJ), A, 理工A(数学物理力学天地生) = Mathematics/ Physics/ Mechanics/ Astronomy

Sprache:

Chinesisch

Weiterer Titel:

Multi-alveolar model and numerical simulation of influence of gravity direction on inhaled particle deposition in human pulmonary acinus region

Beteiligte Personen:

李鹏辉 [VerfasserIn]
徐新喜 [Sonstige Person]
李蓉 [Sonstige Person]
乔扬 [Sonstige Person]

Links:

oversea.cnki.net [lizenzpflichtig]

Themen:

“柱状气管+球状肺泡”架构多肺泡模型
人体肺腺泡
内科学
军事科学院系统工程研究院卫勤保障技术研究所
医药、卫生
医药卫生科技
呼吸系及胸部疾病
引力
数学模拟、近似计算
数理科学和化学
武警后勤学院军事预防医学教研室
理工A(数学物理力学天地生)
肺泡
计算数学
重力方向
颗粒物
Disease of Respiratory System
Gravitation
Gravity direction
Human pulmonary acinus
Mathematics
Mathematics/ Physics/ Mechanics/ Astronomy
Medicine & Public Health
Multi-alveolar model of "columnar trachea+globular alveolar" structure
Particulate matter
Pulmonary alveoli

Anmerkungen:

Author info:LI Peng-hui;XU Xin-xi;LI Rong;QIAO Yang;Institute of Medical Support Technology,Academy of System Engineering,Academy of Military Sciences;Department of Military Preventive Medicine,Logistics University of Chinese People′s Armed Police Force

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

CAJ642726132