β-HCG值在孕早期剖宫产瘢痕妊娠治疗方法选择中的指导意义 : = The value of the level of serum human chorionic gonadotropin-beta for caesarean scar pregnancy in the first trimester
目的寻找一种简单、有效、便于开展的治疗剖宫产瘢痕妊娠(caesarean scar pregnancy,CSP)的方法。方法选取2012年5月至2016年5月邢台市第三医院妇科诊治的24例剖宫产瘢痕妊娠患者进行回顾性分析。入组的患者分为两组,实验组治疗前血β-HCG≤6000mIU/mL,对照组血β-HCG>6000mIU/mL。首先给予药物治疗,1周后复查血β-HCG,降低后在超声引导下清宫,必要时给予宫腔压迫球囊止血。观察药物不良反应发生率、急诊手术率(药物治疗过程中和清宫术中)、球囊压迫率、出血量、住院天数、β-HCG下降至正常时间、阴道流血时间、月经复潮时间。结果实验组8.3%的患者(1/12)用药后因肝功异常行腹腔镜下CSP病灶切除+剖宫产瘢痕修补术。16.7%的患者(2/12)药物治疗两个疗程,8.3%的患者(1/12)清宫术后宫腔压迫球囊止血。清宫术中出血量30 ml～180ml,75%的患者(9/12)住院时间≤10d,25%的患者(3/12)住院时间>10d。术后血β-HCG降至正常的时间为2 w～4w,术后阴道出血持续时间10 d～20d,月经复潮时间30 d～55d。治疗过程中无急诊手术发生。与对照组相比有显著性差异。结论以血β-HCG值为6000mIU/mL为临界值,甲氨蝶呤联合超声引导下清宫术+球囊压迫治疗剖宫产瘢痕妊娠效果确切,风险低,值得推广。.
Objective To explore a simple and effective treatment for caesarean scar pregnancy(CSP) in the first trimester.Methods Clinical data of 24 patients with CSP diagnosed by Xingtai Third Hospital from May 2012 to May 2016 were retrospectively analyzed. The level of serum human chorionic gonadotropin-beta(β-HCG) in experimental group was no more than 6000 mIU/mL, and those with level of β-HCG over 6000 mIU/mL were selected as the control group. All the patients received Methotrexate(MTX) therapy first, then ultrasound-guided suction curettage was performed when levels of β-HCG decreased and Foley tamponade was used in bleeding cases. The incidence of side effect, emergency operation rate, Foley tamponade using rate, blood volume during and after curettage, length of hospital stay,time for thelevel of β-HCG to recover, lasting days of vaginal bleeding and the time for the recovery of menstruation were observed. Results 8.3%(1/12) of patients in the experimental group received CSP lesionectomy and neoplasty of cesarean scar due to abnormal liver function. 16.7%(2/12) of patients received two courses of drug treatment. 8.3%(1/12) of patients used Foley tamponade. The estimated intraoperative blood loss was 30-180 ml, where 75%(9/12) of the patients were hospitalized for no more than 10 days and 25%(3/12) of patients more than 10 days. The time for the level of β-HCG to recover was 2-4 weeks. The postoperative vaginal bleedinglasted for 10-20 days and the time for the recovery of menstruation was 30-55 days. There was no incidence of emergency operation in the experimental group, with statistically significant difference compared to the control group. Conclusions Methotrexate therapy combined with ultrasound-guided suction curettage and Foley tamponade is an effective and safe therapeutic measure for caesarean scar pregnancy, which is worthy promotion with low risk..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019-06-15 2019 |
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| Erschienen: |
2019-06-15 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2019 |
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| Enthalten in: |
Zhong guo xing ke xue - (2019), 06 vom: 15. Juni, Seite 68-72 Original Letters: Enthalten in 中国性科学 (DE-600)2999352-0 (DE-600)2999352-0 北京市 |
| Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
The value of the level of serum human chorionic gonadotropin-beta for caesarean scar pregnancy in the first trimester |
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| Beteiligte Personen: |
张志革 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Themen: |
产科学 |
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| Anmerkungen: |
Author info:ZHANG Zhige;GAO Min;MA Lin;HAN Yue;Departmentof Gynecology, Xingtai Third Hospital |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CAJ63324046X |
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| 245 | 1 | 0 | |a β-HCG值在孕早期剖宫产瘢痕妊娠治疗方法选择中的指导意义 |b = The value of the level of serum human chorionic gonadotropin-beta for caesarean scar pregnancy in the first trimester |
| 246 | 3 | 1 | |a The value of the level of serum human chorionic gonadotropin-beta for caesarean scar pregnancy in the first trimester |
| 264 | 1 | |c 2019-06-15 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
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| 490 | 0 | |a China Academic Journals (CAJ) |a E |a 医药卫生科技 = Medicine & Public Health | |
| 500 | |a Author info:ZHANG Zhige;GAO Min;MA Lin;HAN Yue;Departmentof Gynecology, Xingtai Third Hospital | ||
| 520 | |a 目的寻找一种简单、有效、便于开展的治疗剖宫产瘢痕妊娠(caesarean scar pregnancy,CSP)的方法。方法选取2012年5月至2016年5月邢台市第三医院妇科诊治的24例剖宫产瘢痕妊娠患者进行回顾性分析。入组的患者分为两组,实验组治疗前血β-HCG≤6000mIU/mL,对照组血β-HCG>6000mIU/mL。首先给予药物治疗,1周后复查血β-HCG,降低后在超声引导下清宫,必要时给予宫腔压迫球囊止血。观察药物不良反应发生率、急诊手术率(药物治疗过程中和清宫术中)、球囊压迫率、出血量、住院天数、β-HCG下降至正常时间、阴道流血时间、月经复潮时间。结果实验组8.3%的患者(1/12)用药后因肝功异常行腹腔镜下CSP病灶切除+剖宫产瘢痕修补术。16.7%的患者(2/12)药物治疗两个疗程,8.3%的患者(1/12)清宫术后宫腔压迫球囊止血。清宫术中出血量30 ml～180ml,75%的患者(9/12)住院时间≤10d,25%的患者(3/12)住院时间>10d。术后血β-HCG降至正常的时间为2 w～4w,术后阴道出血持续时间10 d～20d,月经复潮时间30 d～55d。治疗过程中无急诊手术发生。与对照组相比有显著性差异。结论以血β-HCG值为6000mIU/mL为临界值,甲氨蝶呤联合超声引导下清宫术+球囊压迫治疗剖宫产瘢痕妊娠效果确切,风险低,值得推广。 | ||
| 520 | |a Objective To explore a simple and effective treatment for caesarean scar pregnancy(CSP) in the first trimester.Methods Clinical data of 24 patients with CSP diagnosed by Xingtai Third Hospital from May 2012 to May 2016 were retrospectively analyzed. The level of serum human chorionic gonadotropin-beta(β-HCG) in experimental group was no more than 6000 mIU/mL, and those with level of β-HCG over 6000 mIU/mL were selected as the control group. All the patients received Methotrexate(MTX) therapy first, then ultrasound-guided suction curettage was performed when levels of β-HCG decreased and Foley tamponade was used in bleeding cases. The incidence of side effect, emergency operation rate, Foley tamponade using rate, blood volume during and after curettage, length of hospital stay,time for thelevel of β-HCG to recover, lasting days of vaginal bleeding and the time for the recovery of menstruation were observed. Results 8.3%(1/12) of patients in the experimental group received CSP lesionectomy and neoplasty of cesarean scar due to abnormal liver function. 16.7%(2/12) of patients received two courses of drug treatment. 8.3%(1/12) of patients used Foley tamponade. The estimated intraoperative blood loss was 30-180 ml, where 75%(9/12) of the patients were hospitalized for no more than 10 days and 25%(3/12) of patients more than 10 days. The time for the level of β-HCG to recover was 2-4 weeks. The postoperative vaginal bleedinglasted for 10-20 days and the time for the recovery of menstruation was 30-55 days. There was no incidence of emergency operation in the experimental group, with statistically significant difference compared to the control group. Conclusions Methotrexate therapy combined with ultrasound-guided suction curettage and Foley tamponade is an effective and safe therapeutic measure for caesarean scar pregnancy, which is worthy promotion with low risk. | ||
| 610 | 2 | 4 | |a 邢台市第三医院妇科 |
| 650 | 4 | |a 产科学 | |
| 650 | 4 | |a 妇产科学 | |
| 650 | 4 | |a 医药、卫生 | |
| 650 | 4 | |a Gynecology and Obstetrics | |
| 650 | 4 | |a 医药卫生科技 | |
| 650 | 4 | |a Medicine & Public Health | |
| 650 | 4 | |a 妊娠 | |
| 650 | 4 | |a 高危 | |
| 650 | 4 | |a 剖宫产 | |
| 650 | 4 | |a 手术后并发症 | |
| 650 | 4 | |a 清宫术 | |
| 650 | 4 | |a 甲氨蝶呤 | |
| 650 | 4 | |a Pregnancy | |
| 650 | 4 | |a High-risk | |
| 650 | 4 | |a Cesarean section | |
| 650 | 4 | |a Postoperative complications | |
| 650 | 4 | |a Curettage | |
| 650 | 4 | |a Methotrexate(MTX) | |
| 700 | 0 | |a 高敏 |4 oth | |
| 700 | 0 | |a 马琳 |4 oth | |
| 700 | 0 | |a 韩越 |4 oth | |
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