天津市2014-2016年新诊断艾滋病病毒合并丙型肝炎病毒感染者丙型肝炎病毒基因型分布特点 : = HCV genotypes distribution of newly-diagnosed HIV-infected patients in Tianjin of China from 2014 to 2016
目的了解天津市2014-2016年新诊断艾滋病病毒(human immunodeficiency virus,HIV)合并丙型肝炎病毒(hepatitis C virus,HCV)感染者HCV基因型分布特征。方法收集2014-2016年天津市新诊断HIV合并HCV感染者(63例)的性别、年龄、传播途径,并进行HCV基因型检测。同时随机入组天津市第二人民医院同期确诊的65例单纯HCV感染患者,并行HCV基因型检测,统计2组患者HCV基因型分布的差异。结果 2014-2016年,新诊断HIV感染者2 189例,HIV合并HCV感染患者占2.88%(63/2 189),其中HCV RNA阳性率为68.25%(43/63),HCV基因型以3型居多(48.84%,21/43),传播途径以静脉吸毒为主(93.65%,59/63)。单纯HCV感染者1b型最常见(69.23%,45/65),其次为2a型(21.54%,14/65),传播途径主要为输血(90.77%,59/65)。结论天津市新诊断HIV感染者以青年男男性行为人群为主,HIV合并HCV感染者与HCV单纯感染者的HCV基因型分布有明显差异,提示在HIV和HCV抗病毒治疗中需考虑这些情况。.
Objective To understand the distribution of HCV genotypes in HIV/HCV co-infected patients in Tianjin of China from 2014 to 2016. Methods Information such as sex, age, and route of transmission of new-onset HIV/HCV patients from 2014 to 2016 was collected.HCV mono-infected patients in the Second People′s Hospital of Tianjin city during the same period were enrolled randomly.The HCV genotypes were measured in the two groups of patients, and differences in the genotype distributions were analyzed. Results From 2014 to 2016, there were 2 189 new cases of HIV in Tianjin of China.A total of 63 HIV/HCV co-infected cases were identified, and 65 HCV mono-infected patients were enrolled randomly.The HIV/HCV co-infection rate in Tianjin was 2.88%, and the HCV RNA positive rate was 68.25%(43/63).The dominant HCV genotype was type 3(48.84%,21/43), and the main route of transmission was intravenous drug use(93.65%,59/63) in HIV/HCV co-infections.In HCV mono-infection, the dominant HCV genotype was 1 b(69.23%,45/65), followed by type 2 a(21.54%,14/65), and the main route of transmission was blood transfusion(90.77%,59/65). Conclusions New HIV infections in Tianjin are dominated by young men who have sex with men.The main HCV genotype of HIV/HCV co-infections is type 3, followed by type 1 b, and was different from those of HCV mono-infection..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019-03-20 2019 |
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| Erschienen: |
2019-03-20 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2019 |
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| Enthalten in: |
Zhong guo bing du bing za zhi - (2019), 02 vom: 20. März, Seite 81-84 Original Letters: Enthalten in 中国病毒病杂志 (DE-600)2994260-3 (DE-600)2994260-3 北京市 |
| Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
HCV genotypes distribution of newly-diagnosed HIV-infected patients in Tianjin of China from 2014 to 2016 |
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| Beteiligte Personen: |
马萍 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Anmerkungen: |
Author info:MA Ping;WANG Zi-yu;ZHANG De-fa;GAO Li-ying;WU Yue;YU Fang-fang;YU Ai-ping;WEI Min;SHAO Yi-ming;The Second People′s Hospital of Tianjin City |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CAJ628695950 |
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| 245 | 1 | 0 | |a 天津市2014-2016年新诊断艾滋病病毒合并丙型肝炎病毒感染者丙型肝炎病毒基因型分布特点 |b = HCV genotypes distribution of newly-diagnosed HIV-infected patients in Tianjin of China from 2014 to 2016 |
| 246 | 3 | 1 | |a HCV genotypes distribution of newly-diagnosed HIV-infected patients in Tianjin of China from 2014 to 2016 |
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| 500 | |a Author info:MA Ping;WANG Zi-yu;ZHANG De-fa;GAO Li-ying;WU Yue;YU Fang-fang;YU Ai-ping;WEI Min;SHAO Yi-ming;The Second People′s Hospital of Tianjin City | ||
| 520 | |a 目的了解天津市2014-2016年新诊断艾滋病病毒(human immunodeficiency virus,HIV)合并丙型肝炎病毒(hepatitis C virus,HCV)感染者HCV基因型分布特征。方法收集2014-2016年天津市新诊断HIV合并HCV感染者(63例)的性别、年龄、传播途径,并进行HCV基因型检测。同时随机入组天津市第二人民医院同期确诊的65例单纯HCV感染患者,并行HCV基因型检测,统计2组患者HCV基因型分布的差异。结果 2014-2016年,新诊断HIV感染者2 189例,HIV合并HCV感染患者占2.88%(63/2 189),其中HCV RNA阳性率为68.25%(43/63),HCV基因型以3型居多(48.84%,21/43),传播途径以静脉吸毒为主(93.65%,59/63)。单纯HCV感染者1b型最常见(69.23%,45/65),其次为2a型(21.54%,14/65),传播途径主要为输血(90.77%,59/65)。结论天津市新诊断HIV感染者以青年男男性行为人群为主,HIV合并HCV感染者与HCV单纯感染者的HCV基因型分布有明显差异,提示在HIV和HCV抗病毒治疗中需考虑这些情况。 | ||
| 520 | |a Objective To understand the distribution of HCV genotypes in HIV/HCV co-infected patients in Tianjin of China from 2014 to 2016. Methods Information such as sex, age, and route of transmission of new-onset HIV/HCV patients from 2014 to 2016 was collected.HCV mono-infected patients in the Second People′s Hospital of Tianjin city during the same period were enrolled randomly.The HCV genotypes were measured in the two groups of patients, and differences in the genotype distributions were analyzed. Results From 2014 to 2016, there were 2 189 new cases of HIV in Tianjin of China.A total of 63 HIV/HCV co-infected cases were identified, and 65 HCV mono-infected patients were enrolled randomly.The HIV/HCV co-infection rate in Tianjin was 2.88%, and the HCV RNA positive rate was 68.25%(43/63).The dominant HCV genotype was type 3(48.84%,21/43), and the main route of transmission was intravenous drug use(93.65%,59/63) in HIV/HCV co-infections.In HCV mono-infection, the dominant HCV genotype was 1 b(69.23%,45/65), followed by type 2 a(21.54%,14/65), and the main route of transmission was blood transfusion(90.77%,59/65). Conclusions New HIV infections in Tianjin are dominated by young men who have sex with men.The main HCV genotype of HIV/HCV co-infections is type 3, followed by type 1 b, and was different from those of HCV mono-infection. | ||
| 610 | 2 | 4 | |a 天津市第二人民医院 |
| 610 | 2 | 4 | |a 南开大学医学院 |
| 610 | 2 | 4 | |a 中国疾病预防控制中心性病艾滋病预防控制中心 |
| 650 | 4 | |a 传染病 | |
| 650 | 4 | |a 内科学 | |
| 650 | 4 | |a 医药、卫生 | |
| 650 | 4 | |a Infectious Disease | |
| 650 | 4 | |a Digestive System Disease | |
| 650 | 4 | |a Endocrine and Systemic Disease | |
| 650 | 4 | |a 医药卫生科技 | |
| 650 | 4 | |a Medicine & Public Health | |
| 650 | 4 | |a 艾滋病病毒(HIV) | |
| 650 | 4 | |a 丙型肝炎病毒(HCV) | |
| 650 | 4 | |a 合并感染 | |
| 650 | 4 | |a 基因型 | |
| 650 | 4 | |a 分布特征 | |
| 650 | 4 | |a HIV | |
| 650 | 4 | |a HCV | |
| 650 | 4 | |a HIV/HCV coinfection | |
| 650 | 4 | |a HCV genotype | |
| 650 | 4 | |a Distribution characteristics | |
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