心肌标志物检测对急性心肌梗死的快速诊断价值 : = Rapid Diagnostic Value of Myocardial Markers in the Diagnosis of Acute Myocardial Infarction
目的探究心肌标志物检测对急性心肌梗死的快速诊断价值。方法选取2014年1月到2015年12月来我院治疗的急性心肌梗死患者49例,检测患者的心肌肌钙蛋白、血清肌红蛋白及肌酸激酶同工酶水平,与标准正常值对比,分析心肌标志物检测对急性心肌梗死的快速诊断价值。结果入院即刻心肌梗死患者心肌肌钙蛋白、血清肌红蛋白水平明显高于正常标准值(P<0.05),肌酸激酶同工酶水平与正常标准值差异不大,(P>0.05)。入院后急性心肌梗死患者心肌肌钙蛋白水平持续升高,(P<0.05),血清肌红蛋白水平先上升,至1~4h达到峰值后下降,(P<0.05);肌酸激酶同工酶先升高,至1~4h达到峰值后下降(P<0.05)。结论在诊断急性心肌梗死过程中,肌红蛋白用于快速诊断当中敏感性较好,但是特异性不理想,肌钙蛋白敏感性较好,且具有特异性,为急性心肌梗死快速诊断的最佳标志物,肌酸激酶同工酶不是心肌特有的酶类物质,不能作为快速诊断的特异性指标。将三项指标联合检测更有助于提升临床诊断准确性。.
Objective to explore the diagnostic value of myocardial markers for acute myocardial infarction(AMI).Methods 49 patients with acute myocardial infarction from January 2014 to December 2015 in our hospital for treatment of patients,detection of patients with cardiac troponin,myoglobin and serum creatine kinase isoenzyme levels,compared with the standard normal value,analysis of cardiac markers detection value for rapid diagnosis of acute myocardial infarction.Results the levels of cardiac troponin and serum myoglobin in patients with myocardial infarction immediately after admission were significantly higher than the normal standard values(P<0.05).The creatine kinase isoenzyme level was not significantly different from the normal standard value(P>0.05).Myocardial troponin levels in patients with acute myocardial infarction increased continuously after admission,(P< 0.05),serum myoglobin level increased at first,reached its peak at 1~4 hdecreased(P< 0.05);creatine kinase isoenzyme increased to 1~4 hdecreases after reaching the peak(P< 0.05).Conclusion in the diagnosis of acute myocardial infarction in the process of myoglobin for fast diagnosis sensitivity is better,but the specificity is not ideal,troponin and has better sensitivity,specificity,is the best sign of rapid diagnosis of acute myocardial infarction,creatine kinase myocardial enzymes is not unique,not as a specific indicator of rapid diagnosis.Combined detection of three indicators is more helpful to improve the accuracy of clinical diagnosis..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018-03-15 2018 |
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| Erschienen: |
2018-03-15 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2018 |
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| Enthalten in: |
Lin chuang yan jiu - (2018), 03 vom: 15. März, Seite 21-22 Original Letters: Enthalten in 临床研究 (DE-600)2991191-6 (DE-600)2991191-6 陕西省西安市 : [Verlag nicht ermittelbar] |
| Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
Rapid Diagnostic Value of Myocardial Markers in the Diagnosis of Acute Myocardial Infarction |
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| Beteiligte Personen: |
杨小蕊 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Anmerkungen: |
Author info:YANG Xiao-rui;Department of clinical laboratory,Zhengzhou Longhai Hospital |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CAJ592379124 |
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| 245 | 1 | 0 | |a 心肌标志物检测对急性心肌梗死的快速诊断价值 |b = Rapid Diagnostic Value of Myocardial Markers in the Diagnosis of Acute Myocardial Infarction |
| 246 | 3 | 1 | |a Rapid Diagnostic Value of Myocardial Markers in the Diagnosis of Acute Myocardial Infarction |
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| 500 | |a Author info:YANG Xiao-rui;Department of clinical laboratory,Zhengzhou Longhai Hospital | ||
| 520 | |a 目的探究心肌标志物检测对急性心肌梗死的快速诊断价值。方法选取2014年1月到2015年12月来我院治疗的急性心肌梗死患者49例,检测患者的心肌肌钙蛋白、血清肌红蛋白及肌酸激酶同工酶水平,与标准正常值对比,分析心肌标志物检测对急性心肌梗死的快速诊断价值。结果入院即刻心肌梗死患者心肌肌钙蛋白、血清肌红蛋白水平明显高于正常标准值(P<0.05),肌酸激酶同工酶水平与正常标准值差异不大,(P>0.05)。入院后急性心肌梗死患者心肌肌钙蛋白水平持续升高,(P<0.05),血清肌红蛋白水平先上升,至1~4h达到峰值后下降,(P<0.05);肌酸激酶同工酶先升高,至1~4h达到峰值后下降(P<0.05)。结论在诊断急性心肌梗死过程中,肌红蛋白用于快速诊断当中敏感性较好,但是特异性不理想,肌钙蛋白敏感性较好,且具有特异性,为急性心肌梗死快速诊断的最佳标志物,肌酸激酶同工酶不是心肌特有的酶类物质,不能作为快速诊断的特异性指标。将三项指标联合检测更有助于提升临床诊断准确性。 | ||
| 520 | |a Objective to explore the diagnostic value of myocardial markers for acute myocardial infarction(AMI).Methods 49 patients with acute myocardial infarction from January 2014 to December 2015 in our hospital for treatment of patients,detection of patients with cardiac troponin,myoglobin and serum creatine kinase isoenzyme levels,compared with the standard normal value,analysis of cardiac markers detection value for rapid diagnosis of acute myocardial infarction.Results the levels of cardiac troponin and serum myoglobin in patients with myocardial infarction immediately after admission were significantly higher than the normal standard values(P<0.05).The creatine kinase isoenzyme level was not significantly different from the normal standard value(P>0.05).Myocardial troponin levels in patients with acute myocardial infarction increased continuously after admission,(P< 0.05),serum myoglobin level increased at first,reached its peak at 1~4 hdecreased(P< 0.05);creatine kinase isoenzyme increased to 1~4 hdecreases after reaching the peak(P< 0.05).Conclusion in the diagnosis of acute myocardial infarction in the process of myoglobin for fast diagnosis sensitivity is better,but the specificity is not ideal,troponin and has better sensitivity,specificity,is the best sign of rapid diagnosis of acute myocardial infarction,creatine kinase myocardial enzymes is not unique,not as a specific indicator of rapid diagnosis.Combined detection of three indicators is more helpful to improve the accuracy of clinical diagnosis. | ||
| 610 | 2 | 4 | |a 郑州陇海医院检验科 |
| 650 | 4 | |a 诊断学 | |
| 650 | 4 | |a 临床医学 | |
| 650 | 4 | |a 医药、卫生 | |
| 650 | 4 | |a 心脏、血管（循环系）疾病 | |
| 650 | 4 | |a 内科学 | |
| 650 | 4 | |a Clinical Medicine | |
| 650 | 4 | |a Cardiovascular System Disease | |
| 650 | 4 | |a Emergency Medicine | |
| 650 | 4 | |a 医药卫生科技 | |
| 650 | 4 | |a Medicine & Public Health | |
| 650 | 4 | |a 心肌标志物 | |
| 650 | 4 | |a 急性心肌梗死 | |
| 650 | 4 | |a 快速诊断 | |
| 650 | 4 | |a myocardial markers | |
| 650 | 4 | |a acute myocardial infarction | |
| 650 | 4 | |a rapid diagnosis | |
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