基于PLGA聚合物纳米胶束用于癌症治疗研究进展 : = Advance in the study of PLGA copolymer nanomicelles used for cancer therapy

为阐述近年来基于聚乳酸-羟基乙酸共聚物(PLGA)聚合物纳米胶束作为抗癌药物载体的相关研究进展,归纳总结近年来国内外的文献报道,对基于PLGA材料制备纳米胶束作为癌症治疗药物载体的分类、制备方法、相关实验研究进展及其潜在临床应用价值进行探讨研究。结果显示PLGA为经过FDA认证的有良好的生物可降解及生物相容性的高分子聚合物载体材料,基于PLGA的聚合物纳米胶束在传递抗肿瘤药物方面已有广泛的实验研究,是一种极具潜力的新型抗癌药物载体,有望为人类治疗癌症带来福音。.

This review focused on the studies of poly( lactide-co-glycolide)( PLGA) copolymer nanomicelles used as carrier for anticancer agents. We summarized the recent reports about the classification,preparation method,related research and potential clinical application value of PLGA copolymer nanomicelles. PLGA as a kind of biodegradable and biocompatible material has a great application value in delivering anti-cancer agents.The PLGA copolymer nanomicelles are widely used in experimental study for cancer therapy,and bring hope for human cancer treatment..

Medienart:

E-Artikel

Erscheinungsjahr:

2018-02-28

2018

Erschienen:

2018-02-28

Enthalten in:

Zur Gesamtaufnahme - year:2018

Enthalten in:

Zun yi yi xue yuan xue bao - (2018), 01 vom: 28. Feb., Seite 108-113

Original Letters: Enthalten in 遵义医学院学报 (DE-600)2995497-6 (DE-600)2995497-6 贵州省遵义市

Reihe:

China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health

Sprache:

Chinesisch

Weiterer Titel:

Advance in the study of PLGA copolymer nanomicelles used for cancer therapy

Beteiligte Personen:

杨成莉 [VerfasserIn]
王月 [Sonstige Person]
何俊 [Sonstige Person]
曾凡群 [Sonstige Person]

Links:

oversea.cnki.net [lizenzpflichtig]

Themen:

医药、卫生
医药卫生科技
抗癌药物
癌症治疗
聚乳酸-羟基乙酸共聚物
聚合物纳米胶束
肿瘤学
遵义医学院凤冈县联合生物资源健康利用研究所
遵义医学院医学与科技学院
遵义医学院药学院
Anticancer agents
Cancer treatment
Copolymer nanomicelles
Medicine & Public Health
Oncology
PLGA

Anmerkungen:

Author info:Yang Chengli;Wang Yue;He Jun;Zeng Fanqun;School of Pharmacy,Zunyi Medical University;Zunyi Medical University Fenggang County Joint Institute for the Health Use of Biological Resources;Medicine & Technology School of Zunyi Medical University

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

CAJ592317609