紫外线减毒弓形虫ZS1株滋养体免疫小鼠的体液免疫反应 : = HUMORALIMMUNERESPONSEIN MICEVACCINATED WITH UV ATTENUATEDZS1 STRAIN OF TOXOPLASMA GONDII
To explorethe protective effectand the humoralim munereaction of UV attenuated ZS1 strain of Toxoplasma gondiiin mice.The ZS1 strain trophozoites of T.gondii were irradiated by UV light with 2 537 A wavelength , 5cm in distance and withirradiatedtime30 ,60 ,90min and 120min respectively. Mice were dividedinto 4 groups.Group 1 vaccinated alone,group 2 challenged with normal ZS1 trophozoites at 45th day after vaccination ,group 3infected alone,and group 4 was normalcontrol. The mice inoculated with the trophozoitesirradiated 30 minutes were alldead at7 ~8d.Othervaccinated micesurvived normally,and notrophozoite,pseudo cystorcyst wasfound in theirtissues. Mice ofgroup 2 survivedlongerthan thosein group 3 .The value ofIgGin sera detected by ELISAand IHAin responsetosoluble Agof T.gondii wassignificantlyenhancedin both group 1 and group 2 .Ithasbeensuggestedthatthe UV attenuated vaccine of T.gondii of ZS1 strain could induce certain protective im munity in mice,in which humoralim mune may play a role..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
1999-12-30 1999 |
---|---|
Erschienen: |
1999-12-30 |
Enthalten in: |
Zur Gesamtaufnahme - year:1999 |
---|---|
Enthalten in: |
Ji sheng chong bing yu gan ran xing ji bing - (1999), 4 vom: 30. Dez., Seite 7-10 Original Letters: Enthalten in 寄生虫病与感染性疾病 (DE-600)2989511-X (DE-600)2989511-X 四川省成都市 |
Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health China Academic Journals (CAJ), A, 理工A(数学物理力学天地生) = Mathematics/ Physics/ Mechanics/ Astronomy |
---|
Sprache: |
Chinesisch |
---|
Weiterer Titel: |
HUMORALIMMUNERESPONSEIN MICEVACCINATED WITH UV ATTENUATEDZS1 STRAIN OF TOXOPLASMA GONDII |
---|
Beteiligte Personen: |
吕芳丽 [VerfasserIn] |
---|
Links: |
oversea.cnki.net [lizenzpflichtig] |
---|
Themen: |
中山医科大学寄生虫学教研室 |
---|
Umfang: |
4 |
---|
Förderinstitution / Projekttitel: |
|
---|
PPN (Katalog-ID): |
CAJ077657764 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | CAJ077657764 | ||
003 | DE-627 | ||
005 | 20221031121917.0 | ||
007 | cr uuu---uuuuu | ||
008 | 221003s1999 cc |||||o 00| ||chi c | ||
035 | |a (DE-627)CAJ077657764 | ||
035 | |a (SBB-XA)CAJ_SJCB199904002 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a chi | ||
044 | |c XB-CN | ||
084 | |a ASIEN |q DE-1a |2 fid | ||
084 | |a R392.1 |2 clc | ||
100 | 0 | |a 吕芳丽 |e verfasserin |4 aut | |
245 | 1 | 0 | |a 紫外线减毒弓形虫ZS1株滋养体免疫小鼠的体液免疫反应 |b = HUMORALIMMUNERESPONSEIN MICEVACCINATED WITH UV ATTENUATEDZS1 STRAIN OF TOXOPLASMA GONDII |
246 | 3 | 1 | |a HUMORALIMMUNERESPONSEIN MICEVACCINATED WITH UV ATTENUATEDZS1 STRAIN OF TOXOPLASMA GONDII |
264 | 1 | |c 1999-12-30 | |
300 | |a 4 | ||
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
490 | 0 | |a China Academic Journals (CAJ) |a E |a 医药卫生科技 = Medicine & Public Health | |
490 | 0 | |a China Academic Journals (CAJ) |a A |a 理工A(数学物理力学天地生) = Mathematics/ Physics/ Mechanics/ Astronomy | |
520 | |a To explorethe protective effectand the humoralim munereaction of UV attenuated ZS1 strain of Toxoplasma gondiiin mice.The ZS1 strain trophozoites of T.gondii were irradiated by UV light with 2 537 A wavelength , 5cm in distance and withirradiatedtime30 ,60 ,90min and 120min respectively. Mice were dividedinto 4 groups.Group 1 vaccinated alone,group 2 challenged with normal ZS1 trophozoites at 45th day after vaccination ,group 3infected alone,and group 4 was normalcontrol. The mice inoculated with the trophozoitesirradiated 30 minutes were alldead at7 ~8d.Othervaccinated micesurvived normally,and notrophozoite,pseudo cystorcyst wasfound in theirtissues. Mice ofgroup 2 survivedlongerthan thosein group 3 .The value ofIgGin sera detected by ELISAand IHAin responsetosoluble Agof T.gondii wassignificantlyenhancedin both group 1 and group 2 .Ithasbeensuggestedthatthe UV attenuated vaccine of T.gondii of ZS1 strain could induce certain protective im munity in mice,in which humoralim mune may play a role. | ||
610 | 2 | 4 | |a 中山医科大学寄生虫学教研室 |
610 | 2 | 4 | |a 广州 |
650 | 4 | |a 医药卫生科技 | |
650 | 4 | |a Medicine & Public Health | |
650 | 4 | |a 理工A(数学物理力学天地生) | |
650 | 4 | |a Mathematics/ Physics/ Mechanics/ Astronomy | |
650 | 4 | |a 医学免疫学 | |
650 | 4 | |a 基础医学 | |
650 | 4 | |a 医药、卫生 | |
650 | 4 | |a 弓形虫 | |
650 | 4 | |a 紫外线减毒 | |
650 | 4 | |a IgG | |
700 | 0 | |a 郑焕钦 |4 oth | |
700 | 0 | |a 陈观今 |4 oth | |
773 | 0 | 8 | |6 880-01 |i Enthalten in |t Ji sheng chong bing yu gan ran xing ji bing |d Si chuan sheng cheng du shi, 1993 |g (1999), 4 vom: 30. Dez., Seite 7-10 |h Online-Ressource |w (DE-627)CAJ07764641X |w (DE-600)2989511-X |7 nnns |
773 | 1 | 8 | |g year:1999 |g number:4 |g day:30 |g month:12 |g pages:7-10 |g extent:4 |
856 | 4 | 0 | |u https://oversea.cnki.net/kcms/detail/detail.aspx?dbcode=CJFD&filename=SJCB199904002 |x Verlag |z lizenzpflichtig |
856 | 4 | 0 | |u http://erf.sbb.spk-berlin.de/han/caj/oversea.cnki.net/kcms/detail/detail.aspx?dbcode=CJFD&filename=SJCB199904002 |x Verlag |y CrossAsia Link |z Deutschlandweit zugänglich |
880 | 0 | 8 | |6 773-01/Hans |i Enthalten in |t 寄生虫病与感染性疾病 |d 四川省成都市 |h Online-Ressource |w (DE-627)CAJ07764641X |w (DE-600)2989511-X |7 nnns |
912 | |a ZDB-1-CAJ | ||
912 | |a GBV_NL_CAJ | ||
912 | |a FID-ASIEN | ||
912 | |a SSG-OLC-OA3.1A | ||
912 | |a SSG-OLC-CAJ | ||
936 | u | w | |j 1999 |e 4 |b 30 |c 12 |h 7-10 |g 4 |
951 | |a AR | ||
952 | |j 1999 |e 4 |b 30 |c 12 |h 7-10 |g 4 | ||
980 | |2 11 |1 01 |x 0001 |b 077612388 |c 00 |f 5:FIDXASIA |d --%%-- |e --%%-- |j --%%-- |y k |z 03-10-22 | ||
981 | |2 11 |1 01 |x 0001 |y CrossAsia Link |r http://erf.sbb.spk-berlin.de/han/caj/oversea.cnki.net/kcms/detail/detail.aspx?dbcode=CJFD&filename=SJCB199904002 |