Diabetes in Old Age
Title Page -- Copyright Page -- Contents -- Preface -- Foreword -- List of contributors -- Section A Pathophysiology, screening and diagnosis -- Chapter 1 Pathophysiology of diabetes in older people -- 1.1 Introduction -- 1.2 Diet and diabetes in the elderly -- 1.3 Other factors -- 1.4 Metabolic alterations -- 1.5 Molecular biology studies -- 1.6 Glucose counter-regulation -- 1.7 Conclusions -- Acknowledgments -- References -- Chapter 2 Type 1 diabetes in older age -- 2.1 Introduction -- 2.2 Goals in the management of type 1 diabetes in older adults -- 2.3 Complications and co-morbidities -- 2.4 Hypoglycemia -- 2.5 Multidisciplinary team approach -- 2.6 Long-term care -- 2.7 Conclusion -- References -- Chapter 3 Preventative strategies -- 3.1 Introduction -- 3.2 Diabetes and cardiovascular disease -- 3.3 Trials to prevent or delay progression from impaired glucose tolerance to diabetes -- 3.4 Diabetes prevention trials using lifestyle modification programs -- 3.5 The Da Qing study -- 3.6 The Finnish Diabetes Prevention Study -- 3.7 The Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study -- 3.8 Translation of clinical trial results into clinical practice -- References -- Chapter 4 Diagnosis and screening -- 4.1 Introduction -- 4.2 Definition of being old -- 4.3 Definition of diabetes -- 4.4 Why investigate diabetes? Diagnostic objectives -- 4.5 How to recognize diabetes mellitus: Diagnostic tools -- 4.6 Diagnostic criteria -- 4.7 Diagnostic approach -- 4.8 Screening -- References -- Chapter 5 Assessment procedures including comprehensive geriatric assessment -- 5.1 Diabetes in the aging population -- 5.2 Geriatric syndromes in an aging population -- 5.3 CGA and the geriatrics approach to diabetes -- 5.4 Conclusion -- References -- Section B Vascular risk factors and complications -- Chapter 6 Peripheral arterial disease.
6.1 Introduction -- 6.2 Epidemiology of PAD -- 6.3 Pathophysiology -- 6.4 Clinical presentation -- 6.5 Diagnostic methods -- 6.6 Treatment -- 6.7 Conclusions -- References -- Chapter 7 Coronary heart disease -- 7.1 Introduction -- 7.2 Effect of aging and diabetes on the cardiovascular system -- 7.3 Epidemiology of CHD -- 7.4 Cardiovascular risk -- 7.5 Prevention and management of CHD -- 7.6 Conclusion -- References -- Chapter 8 Chronic kidney disease related to diabetes in older patients -- 8.1 Introduction -- 8.2 Relevant epidemiological information and forms of presentation -- 8.3 Pathophysiological mechanisms involved in diabetic kidney disease -- 8.4 Metabolic alterations, particularly hyperglycemia -- 8.5 Conclusion -- References -- Chapter 9 Visual loss in people with diabetes in old age -- 9.1 Introductions and background -- 9.2 Causes of visual impairment -- 9.3 Conclusions -- References -- Chapter 10 Diabetes foot disease -- 10.1 Introduction -- 10.2 Foot disease in older people -- 10.3 Risk factors for foot disease -- 10.4 Diabetic neuropathy -- 10.5 Charcot's neuropathy -- 10.6 Peripheral arterial disease -- 10.7 PAD and foot ulcer healing -- 10.8 Other risk factors -- 10.9 Classification of diabetic foot ulcers -- 10.10 Assessment of foot at risk -- 10.11 Principles of management -- 10.12 Treatment of diabetic foot ulcers -- 10.13 Control of infection -- 10.14 Improvement in wound condition -- 10.15 Surgery -- 10.16 Conclusion -- References -- Chapter 11 Diabetes, neuropathy, and old age -- 11.1 Introduction -- 11.2 Frequency of neuropathy development -- 11.3 Types of diabetic peripheral neuropathy -- 11.4 Diagnosis and evaluation -- 11.5 Management -- 11.6 Summary -- References -- Chapter 12 Sensory disabilities in people with diabetes -- 12.1 Introduction -- 12.2 The five senses -- 12.3 Prevent sensory disability -- 12.4 Seeing.
12.5 Hearing -- 12.6 Smelling and tasting (olfaction and gustation) -- 12.7 Impaired bodily sensation -- 12.8 Medication and sensory impairment -- 12.9 Sensory assessment -- 12.10 Conclusions -- References -- Chapter 13 Sexual health and wellbeing -- 13.1 Why is sexuality important in older age? -- 13.2 What sexual problems do we see associated with diabetes in aging? -- 13.3 Impact of aging in men and women -- 13.4 Hormones and aging in men -- 13.5 Diabetes and sexuality in women -- 13.6 Cardiovascular drugs and sexual function in men and women -- 13.7 Osteoporosis, frailty, recurrent falls, and muscle strength -- 13.8 Cognitive function -- 13.9 Mood and depression -- 13.10 Testosterone and Alzheimer's disease -- 13.11 Testosterone and quality of life -- 13.12 Long-term safety of testosterone therapy -- 13.13 Effects of androgen ablation therapy -- 13.14 Conclusions -- References -- Chapter 14 eHealth and diabetes: Designing a novel system for remotely monitoring older adults with type 2 diabetes -- 14.1 Introduction -- 14.2 An overview of ICT solutions for managing chronic conditions -- 14.3 Diabetes management apps: strengths and weaknesses -- 14.4 Diabetes and older people: looking for a novel approach -- 14.5 Conclusion -- References -- Section C Treatment and care issues -- Chapter 15 Insulin resistance and the metabolic syndrome -- 15.1 Introduction -- 15.2 Insulin physiology and metabolic regulation -- 15.3 Insulin action: Relation to aging -- 15.4 Implications of insulin resistance for cardiometabolic disease -- 15.5 Clinical research methods for assessing insulin action -- 15.6 Studies of insulin action in older people -- 15.7 Insulin resistance in clinical practice -- 15.8 Metabolic syndrome: clinical definitions -- 15.9 Utility of the metabolic syndrome in clinical practice -- 15.10 Prevalence of the metabolic syndrome.
15.11 Pathogenesis of the metabolic syndrome -- 15.12 Overweight and obesity -- 15.13 Role of insulin resistance -- 15.14 Emerging role of insulin resistance and the metabolic syndrome in age-related disorders -- 15.15 Controversies in prevention and therapy of the metabolic syndrome -- References -- Chapter 16 Diabetes and functional limitation: The emergence of frailty and disability -- 16.1 Introduction -- 16.2 Functional limitation and diabetes: early background studies -- 16.3 Diabetes and frailty -- 16.4 Diabetes and disability -- 16.5 Functional assessment in varying clinical sectors -- 16.6 Conclusions -- References -- Chapter 17 Metabolic decompensation in older people -- 17.1 Introduction -- 17.2 Hypoglycemia -- 17.3 Diabetic ketoacidosis and hyperosmolar hyperglycemic state in the elderly -- 17.4 Pathogenesis of DKA and HHS -- 17.5 Diagnosis of DKA and HHS -- 17.6 Conclusion -- References -- Chapter 18 Nutrition management -- 18.1 Introduction -- 18.2 Basis of nutrition support -- 18.3 Nutrition and normal aging -- 18.4 Under- and malnutrition in older people -- 18.5 Over-nutrition and obesity in older people -- 18.6 Nutrition assessment -- 18.7 Brief review of nutritional guidelines -- 18.8 Current dietary recommendations: Applications to older people with diabetes -- 18.9 Energy intake: Carbohydrates and fats -- 18.10 Activity and exercise -- 18.11 Protein -- 18.12 Fiber -- 18.13 Sodium -- 18.14 Alcohol -- 18.15 Vitamins and minerals -- 18.16 Specific mineral and vitamin deficiencies -- 18.17 Other vitamins and minerals -- 18.18 Oral nutrition supplements -- 18.19 Prebiotics and probiotics -- 18.20 Artificial nutrition -- 18.21 Is artificial nutritional support necessary? -- 18.22 Delivery routes for artificial nutritional -- 18.23 Enteral tube feeding -- 18.24 Composition of specialist feeds to manage hyperglycemia.
18.25 Administering medicines with enteral feeding -- 18.26 Complications of enteral nutrition -- 18.27 Parenteral nutrition -- 18.28 Ethical issues -- 18.29 Oral health, swallowing, and dysphagia -- 18.30 Pressure ulcers and the diabetic foot -- 18.31 Summary -- Acknowledgments -- References -- Chapter 19 Physical exercise management -- 19.1 Introduction -- 19.2 The effects of exercise interventions on glycemic control in older people -- 19.3 The effects of endurance training -- 19.4 The effects of resistance training -- 19.5 The effects of combined resistance and endurance training -- 19.6 Functional capacity in older diabetic patients -- 19.7 Resistance training improves muscle strength, power, and functional capacity in older people with diabetes -- 19.8 High-velocity resistance training in older patients with diabetes -- 19.9 Endurance training and cardiovascular function in older patients with diabetes -- 19.10 Diabetes, cognitive impairment, and exercise -- 19.11 Conclusions: Special considerations when prescribing exercise in older type 2 diabetic patients -- References -- Chapter 20 Medicines, pharmacovigilance, and the importance of undertaking comprehensive assessments and regular medicine reviews -- 20.1 Introduction -- 20.2 Medicine-related vulnerability and older people -- 20.3 Polypharmacy -- 20.4 Pharmacovigilance -- 20.5 Common medicine-related issues in older people -- 20.6 Medicine adherence -- 20.12 Antipsychotic, antihypertensive, and lipid- and glucose-lowering medicines -- 20.13 Infrequent blood glucose testing -- 20.14 Frailty and cognitive changes -- 20.15 Falls risk -- 20.16 Health professionals, people with diabetes, and/or family medicine-related beliefs and attitudes -- 20.17 Strategies that can help reduce medicine-related adverse events -- 20.18 The five rights of administering medicines.
20.19 Medicine reviews and risk assessments.
Medienart: |
E-Book |
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Erscheinungsjahr: |
2017 ©2015 |
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Erschienen: |
Somerset: John Wiley & Sons, Incorporated ; 2017 ©2015 |
Ausgabe: |
4th ed |
Sprache: |
Englisch |
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Beteiligte Personen: |
Sinclair, Alan J. [VerfasserIn] |
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Links: |
Volltext [lizenzpflichtig] |
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ISBN: |
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Themen: |
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Umfang: |
1 Online-Ressource (573 pages) |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
881512311 |
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520 | |a Title Page -- Copyright Page -- Contents -- Preface -- Foreword -- List of contributors -- Section A Pathophysiology, screening and diagnosis -- Chapter 1 Pathophysiology of diabetes in older people -- 1.1 Introduction -- 1.2 Diet and diabetes in the elderly -- 1.3 Other factors -- 1.4 Metabolic alterations -- 1.5 Molecular biology studies -- 1.6 Glucose counter-regulation -- 1.7 Conclusions -- Acknowledgments -- References -- Chapter 2 Type 1 diabetes in older age -- 2.1 Introduction -- 2.2 Goals in the management of type 1 diabetes in older adults -- 2.3 Complications and co-morbidities -- 2.4 Hypoglycemia -- 2.5 Multidisciplinary team approach -- 2.6 Long-term care -- 2.7 Conclusion -- References -- Chapter 3 Preventative strategies -- 3.1 Introduction -- 3.2 Diabetes and cardiovascular disease -- 3.3 Trials to prevent or delay progression from impaired glucose tolerance to diabetes -- 3.4 Diabetes prevention trials using lifestyle modification programs -- 3.5 The Da Qing study -- 3.6 The Finnish Diabetes Prevention Study -- 3.7 The Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study -- 3.8 Translation of clinical trial results into clinical practice -- References -- Chapter 4 Diagnosis and screening -- 4.1 Introduction -- 4.2 Definition of being old -- 4.3 Definition of diabetes -- 4.4 Why investigate diabetes? Diagnostic objectives -- 4.5 How to recognize diabetes mellitus: Diagnostic tools -- 4.6 Diagnostic criteria -- 4.7 Diagnostic approach -- 4.8 Screening -- References -- Chapter 5 Assessment procedures including comprehensive geriatric assessment -- 5.1 Diabetes in the aging population -- 5.2 Geriatric syndromes in an aging population -- 5.3 CGA and the geriatrics approach to diabetes -- 5.4 Conclusion -- References -- Section B Vascular risk factors and complications -- Chapter 6 Peripheral arterial disease | ||
520 | |a 6.1 Introduction -- 6.2 Epidemiology of PAD -- 6.3 Pathophysiology -- 6.4 Clinical presentation -- 6.5 Diagnostic methods -- 6.6 Treatment -- 6.7 Conclusions -- References -- Chapter 7 Coronary heart disease -- 7.1 Introduction -- 7.2 Effect of aging and diabetes on the cardiovascular system -- 7.3 Epidemiology of CHD -- 7.4 Cardiovascular risk -- 7.5 Prevention and management of CHD -- 7.6 Conclusion -- References -- Chapter 8 Chronic kidney disease related to diabetes in older patients -- 8.1 Introduction -- 8.2 Relevant epidemiological information and forms of presentation -- 8.3 Pathophysiological mechanisms involved in diabetic kidney disease -- 8.4 Metabolic alterations, particularly hyperglycemia -- 8.5 Conclusion -- References -- Chapter 9 Visual loss in people with diabetes in old age -- 9.1 Introductions and background -- 9.2 Causes of visual impairment -- 9.3 Conclusions -- References -- Chapter 10 Diabetes foot disease -- 10.1 Introduction -- 10.2 Foot disease in older people -- 10.3 Risk factors for foot disease -- 10.4 Diabetic neuropathy -- 10.5 Charcot's neuropathy -- 10.6 Peripheral arterial disease -- 10.7 PAD and foot ulcer healing -- 10.8 Other risk factors -- 10.9 Classification of diabetic foot ulcers -- 10.10 Assessment of foot at risk -- 10.11 Principles of management -- 10.12 Treatment of diabetic foot ulcers -- 10.13 Control of infection -- 10.14 Improvement in wound condition -- 10.15 Surgery -- 10.16 Conclusion -- References -- Chapter 11 Diabetes, neuropathy, and old age -- 11.1 Introduction -- 11.2 Frequency of neuropathy development -- 11.3 Types of diabetic peripheral neuropathy -- 11.4 Diagnosis and evaluation -- 11.5 Management -- 11.6 Summary -- References -- Chapter 12 Sensory disabilities in people with diabetes -- 12.1 Introduction -- 12.2 The five senses -- 12.3 Prevent sensory disability -- 12.4 Seeing | ||
520 | |a 12.5 Hearing -- 12.6 Smelling and tasting (olfaction and gustation) -- 12.7 Impaired bodily sensation -- 12.8 Medication and sensory impairment -- 12.9 Sensory assessment -- 12.10 Conclusions -- References -- Chapter 13 Sexual health and wellbeing -- 13.1 Why is sexuality important in older age? -- 13.2 What sexual problems do we see associated with diabetes in aging? -- 13.3 Impact of aging in men and women -- 13.4 Hormones and aging in men -- 13.5 Diabetes and sexuality in women -- 13.6 Cardiovascular drugs and sexual function in men and women -- 13.7 Osteoporosis, frailty, recurrent falls, and muscle strength -- 13.8 Cognitive function -- 13.9 Mood and depression -- 13.10 Testosterone and Alzheimer's disease -- 13.11 Testosterone and quality of life -- 13.12 Long-term safety of testosterone therapy -- 13.13 Effects of androgen ablation therapy -- 13.14 Conclusions -- References -- Chapter 14 eHealth and diabetes: Designing a novel system for remotely monitoring older adults with type 2 diabetes -- 14.1 Introduction -- 14.2 An overview of ICT solutions for managing chronic conditions -- 14.3 Diabetes management apps: strengths and weaknesses -- 14.4 Diabetes and older people: looking for a novel approach -- 14.5 Conclusion -- References -- Section C Treatment and care issues -- Chapter 15 Insulin resistance and the metabolic syndrome -- 15.1 Introduction -- 15.2 Insulin physiology and metabolic regulation -- 15.3 Insulin action: Relation to aging -- 15.4 Implications of insulin resistance for cardiometabolic disease -- 15.5 Clinical research methods for assessing insulin action -- 15.6 Studies of insulin action in older people -- 15.7 Insulin resistance in clinical practice -- 15.8 Metabolic syndrome: clinical definitions -- 15.9 Utility of the metabolic syndrome in clinical practice -- 15.10 Prevalence of the metabolic syndrome | ||
520 | |a 15.11 Pathogenesis of the metabolic syndrome -- 15.12 Overweight and obesity -- 15.13 Role of insulin resistance -- 15.14 Emerging role of insulin resistance and the metabolic syndrome in age-related disorders -- 15.15 Controversies in prevention and therapy of the metabolic syndrome -- References -- Chapter 16 Diabetes and functional limitation: The emergence of frailty and disability -- 16.1 Introduction -- 16.2 Functional limitation and diabetes: early background studies -- 16.3 Diabetes and frailty -- 16.4 Diabetes and disability -- 16.5 Functional assessment in varying clinical sectors -- 16.6 Conclusions -- References -- Chapter 17 Metabolic decompensation in older people -- 17.1 Introduction -- 17.2 Hypoglycemia -- 17.3 Diabetic ketoacidosis and hyperosmolar hyperglycemic state in the elderly -- 17.4 Pathogenesis of DKA and HHS -- 17.5 Diagnosis of DKA and HHS -- 17.6 Conclusion -- References -- Chapter 18 Nutrition management -- 18.1 Introduction -- 18.2 Basis of nutrition support -- 18.3 Nutrition and normal aging -- 18.4 Under- and malnutrition in older people -- 18.5 Over-nutrition and obesity in older people -- 18.6 Nutrition assessment -- 18.7 Brief review of nutritional guidelines -- 18.8 Current dietary recommendations: Applications to older people with diabetes -- 18.9 Energy intake: Carbohydrates and fats -- 18.10 Activity and exercise -- 18.11 Protein -- 18.12 Fiber -- 18.13 Sodium -- 18.14 Alcohol -- 18.15 Vitamins and minerals -- 18.16 Specific mineral and vitamin deficiencies -- 18.17 Other vitamins and minerals -- 18.18 Oral nutrition supplements -- 18.19 Prebiotics and probiotics -- 18.20 Artificial nutrition -- 18.21 Is artificial nutritional support necessary? -- 18.22 Delivery routes for artificial nutritional -- 18.23 Enteral tube feeding -- 18.24 Composition of specialist feeds to manage hyperglycemia | ||
520 | |a 18.25 Administering medicines with enteral feeding -- 18.26 Complications of enteral nutrition -- 18.27 Parenteral nutrition -- 18.28 Ethical issues -- 18.29 Oral health, swallowing, and dysphagia -- 18.30 Pressure ulcers and the diabetic foot -- 18.31 Summary -- Acknowledgments -- References -- Chapter 19 Physical exercise management -- 19.1 Introduction -- 19.2 The effects of exercise interventions on glycemic control in older people -- 19.3 The effects of endurance training -- 19.4 The effects of resistance training -- 19.5 The effects of combined resistance and endurance training -- 19.6 Functional capacity in older diabetic patients -- 19.7 Resistance training improves muscle strength, power, and functional capacity in older people with diabetes -- 19.8 High-velocity resistance training in older patients with diabetes -- 19.9 Endurance training and cardiovascular function in older patients with diabetes -- 19.10 Diabetes, cognitive impairment, and exercise -- 19.11 Conclusions: Special considerations when prescribing exercise in older type 2 diabetic patients -- References -- Chapter 20 Medicines, pharmacovigilance, and the importance of undertaking comprehensive assessments and regular medicine reviews -- 20.1 Introduction -- 20.2 Medicine-related vulnerability and older people -- 20.3 Polypharmacy -- 20.4 Pharmacovigilance -- 20.5 Common medicine-related issues in older people -- 20.6 Medicine adherence -- 20.12 Antipsychotic, antihypertensive, and lipid- and glucose-lowering medicines -- 20.13 Infrequent blood glucose testing -- 20.14 Frailty and cognitive changes -- 20.15 Falls risk -- 20.16 Health professionals, people with diabetes, and/or family medicine-related beliefs and attitudes -- 20.17 Strategies that can help reduce medicine-related adverse events -- 20.18 The five rights of administering medicines | ||
520 | |a 20.19 Medicine reviews and risk assessments | ||
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