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|a 610.28
|2 23
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|a Biomedical engineering
|b frontier research and converging technologies
|c Hanjoong Jo, Ho-Wook Jun, Jennifer Shin, SangHoon Lee, editors
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|a Cham
|b Springer
|c [2016]
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| 300 |
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|a Online-Ressource (xvi, 511 pages)
|b color illustrations
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a Computermedien
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|a Online-Ressource
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|2 rdacarrier
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|a Biosystems & biorobotics
|v volume 9
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| 490 |
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|a Biosystems and Biorobotics Ser.
|v v.9
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| 500 |
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|a Includes author index
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|a Preface; Contents; Acknowledgement; About the Editors; Part I Nanotechnology and Nanomedicine; Nanoparticles for Imaging and Non-viral Gene Therapy; 1 Introduction; 2 Nanoparticles as a Gene Carrier; 2.1 Liposomes; 2.2 Polymers; 2.3 Inorganic Nanoparticles; 2.4 Other Carriers; 2.5 Hybrids; 3 Nanoparticles as a Molecular Contrast Agent; 3.1 Imaging Contrast Agents Used for Gene Delivery; 4 Targeting and Controlled Release of Genes; 4.1 Targeting; 4.2 Controlled Release of Genes; 5 Therapeutic Efficacy and Safety; 5.1 Current Status of Non-viral Gene Delivery with Molecular Imaging; References
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| 505 |
8 |
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|a Nanoparticles for Pancreatic Islet Imaging1 Introduction; 2 Intracellular Delivery of Nanoparticles Into Islet Cells; 2.1 Nanoparticle Uptake for Islet Labeling; 2.2 Cationic Materialconjugated Nanoparticles to Enhance the Labeling Efficiency of Islets; 2.3 Antibody-conjugated Nanoparticles to Enhance the Labeling Efficiency of Islets; 2.4 Sulfonylurea Receptor-Targeted Nanoparticles; 2.5 Glucagon Like Peptide-1 Receptor-Targeted Nanoparticles; 2.6 Glucose Transporter-Targeted Nanoparticles; 2.7 Vesicular Monoamine Transporter-Targeted Nanoparticles; 3 Conjugation of Nanoparticles with Islets
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|a 3.1 Polymer Linker-Mediated Conjugation of Nanoparticles with the Islets3.2 Ligand-Mediated Conjugation of Nanoparticles with the Islets; 4 Conclusion and Perspective; References; Dendritic Nanomaterials for Therapeutic and Diagnostic Applications; 1 Introduction to Dendritic Nanomaterials; 1.1 Dendrimers; 1.2 Dendrons; 1.3 Hybrid Nanoparticles; 1.4 Dendrimersomes; 2 Fundamental Understanding of Biological Behaviors of Dendritic Nanomaterials; 2.1 Physical Property-Dependent Non-specific Cell Interactions; 2.2 Cell-Specific Recognition and Multivalent Binding Effect
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|a 2.3 Stimuli-Responsive Processes for Drug Delivery2.4 Biodistribution and Pharmacokinetics; 3 Biomedical Applications; 3.1 Drug Delivery; 3.2 Gene Delivery; 3.3 Diagnostics and Prognostics; 3.4 Detoxification and Prophylaxis; 4 Challenges in Clinical Translation; 5 Conclusions and Future Perspectives; References; Nanomaterials for Diagnostic Imaging of the Brain; 1 Introduction; 2 Bioimaging Modalities for Brain Diagnosis; 2.1 Computerized Axial Tomography (CT); 2.2 Magnetic Resonance Imaging (MRI); 2.3 Positron Emission Tomography (PET); 3 Biomolecular Carrier of Imaging Contrast Agents
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| 505 |
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|a 3.1 Radiopharmaceutical Analogs4 Nanoparticle Carrier of Imaging Contrast Agents; 4.1 Liposomal Carriers; 4.2 Nanoparticles Enabling Targeting and Theranostics; 4.3 Nanoparticles Enabling Multimodal Imaging; 5 Conclusion; References; Part II Regenerative Medicine; Cellular Interactions with Self-assembled Biomaterials and Composites for Bone Tissue Engineering; 1 Introduction; 2 Cellular Interactions; 3 Current Biomaterials for Bone Grafting: Strengths and Weaknesses; 4 Principles of Bone Tissue Engineering; 5 Self-assembling Biomaterials; 5.1 Peptide Based Supramolecular Systems
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| 505 |
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|a 6 Self-assembling Biomaterials for Scaffold Based Bone Tissue Regeneration
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| 520 |
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|a Intro -- Preface -- Contents -- Acknowledgement -- About the Editors -- Part I Nanotechnology and Nanomedicine -- Nanoparticles for Imaging and Non-viral Gene Therapy -- 1 Introduction -- 2 Nanoparticles as a Gene Carrier -- 2.1 Liposomes -- 2.2 Polymers -- 2.3 Inorganic Nanoparticles -- 2.4 Other Carriers -- 2.5 Hybrids -- 3 Nanoparticles as a Molecular Contrast Agent -- 3.1 Imaging Contrast Agents Used for Gene Delivery -- 4 Targeting and Controlled Release of Genes -- 4.1 Targeting -- 4.2 Controlled Release of Genes -- 5 Therapeutic Efficacy and Safety -- 5.1 Current Status of Non-viral Gene Delivery with Molecular Imaging -- References -- Nanoparticles for Pancreatic Islet Imaging -- 1 Introduction -- 2 Intracellular Delivery of Nanoparticles Into Islet Cells -- 2.1 Nanoparticle Uptake for Islet Labeling -- 2.2 Cationic Materialconjugated Nanoparticles to Enhance the Labeling Efficiency of Islets -- 2.3 Antibody-conjugated Nanoparticles to Enhance the Labeling Efficiency of Islets -- 2.4 Sulfonylurea Receptor-Targeted Nanoparticles -- 2.5 Glucagon Like Peptide-1 Receptor-Targeted Nanoparticles -- 2.6 Glucose Transporter-Targeted Nanoparticles -- 2.7 Vesicular Monoamine Transporter-Targeted Nanoparticles -- 3 Conjugation of Nanoparticles with Islets -- 3.1 Polymer Linker-Mediated Conjugation of Nanoparticles with the Islets -- 3.2 Ligand-Mediated Conjugation of Nanoparticles with the Islets -- 4 Conclusion and Perspective -- References -- Dendritic Nanomaterials for Therapeutic and Diagnostic Applications -- 1 Introduction to Dendritic Nanomaterials -- 1.1 Dendrimers -- 1.2 Dendrons -- 1.3 Hybrid Nanoparticles -- 1.4 Dendrimersomes -- 2 Fundamental Understanding of Biological Behaviors of Dendritic Nanomaterials -- 2.1 Physical Property-Dependent Non-specific Cell Interactions -- 2.2 Cell-Specific Recognition and Multivalent Binding Effect.
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|a Online-Ausg.
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|a Biomedical engineering
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|a Biomedical engineering
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|a Jun, Ho-Wook
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|a Shin, Jennifer
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