The Local Cardiac Renin-Angiotensin Aldosterone System
Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is produced, synthesized and indeed, present in many organisms including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the local cardiac renin-angiotensin aldosterone system.Cardiovascular, renal and hypertension oriented physicians, investigators and scientists would find this book of interest.Edward D. Frohlich, M.D., M.A.C.P, F.A.C.C., is the Alton Ochsner Distinguished Scientist at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans. He is past Editor-in-Chief of the American Heart Association journal HYPERTENSION.Richard N. Re, M.D., is the Section Head, Hypertension at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Ochsner's Scientific Director of Research..
| Medienart: |
E-Book |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
s.l.: Springer-Verlag ; 2009 |
| Ausgabe: |
2. Aufl. |
| Reproduktion: |
Online-Ausg. ; 2010 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Frohlich, Edward D. [VerfasserIn] |
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| Links: |
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| ISBN: |
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| Nlm: |
WG 106 |
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| Themen: |
Heart |
| Anmerkungen: |
Includes bibliographical references and index |
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| Umfang: |
Online Ressource (1500 KB, 184 S.) |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
679002960 |
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| 100 | 1 | |a Frohlich, Edward D. |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Local Cardiac Renin-Angiotensin Aldosterone System |
| 250 | |a 2. Aufl. | ||
| 264 | 1 | |a [s.l.] |b Springer-Verlag |c 2009 | |
| 300 | |a Online Ressource (1500 KB, 184 S.) | ||
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| 500 | |a Includes bibliographical references and index | ||
| 505 | 8 | 0 | |a Preface; Contents; Contributors; 1 Are Local Renin--Angiotensin Systems the Focal Pointsfor Understanding Salt Sensitivity in Hypertension?; References; 2 Newer Insights into the Biochemical Physiology of the ReninAngiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12); References; 3 Renin, Prorenin, and the (Pro)renin Receptor; References; 4 Intracellular Accumulation and Nuclear Traffickingof Angiotensin II and the Angiotensin II Type 1 Receptor; References |
| 505 | 8 | 0 | |a 5 Pathophysiologic Implications of Cell Swellingin the Failing Heart: Influence of Intracrineand Extracellular Renin--Angiotensin SystemsReferences; 6 Exploiting Rat Genetics to Investigate Hypertensive End-Organ Damage; References; 7 Alternative Renin Transcripts and Functions of Cytoplasmatic Renin; References; 8 Novel Aspects of the Cardiac ReninAngiotensin System; References; 9 Intracrine Function from Angiotensin to Stem Cells; References; 10 Renin Cell Identity and Homeostasis; References |
| 505 | 8 | 0 | |a 11 Role of Renal Aminopeptidases and Angiotensin Type-2 (AT 2 ) Receptors in Sodium Excretion and HypertensionReferences; 12 Intrarenal Angiotensin II Augmentation in Hypertension; References; 13 Collecting Duct Renin: A Critical Linkin Angiotensin II-Dependent Hypertension; References; 14 ReninAngiotensinAldosterone System and Cardiomyocyte Apoptosis in Hypertensive Heart Disease; References; 15 Upregulation of Angiotensin II Type 2 Receptor (agtr2) Attenuates Atherosclerotic Lesion Formation and Enhances Apoptosis in the LDL Receptor Knockout Mice Fed High Cholesterol Diet; References |
| 505 | 8 | 0 | |a 16 Salt and Heart: RAAS InvolvementReferences; 17 Cardiac Effects of Aldosterone, the Bad, but Is There Also a Good ?; References; Subject Index; |
| 505 | 8 | 0 | |a Are Local Renin-Angiotensin Systems the Focal Points for Understanding Salt Sensitivity in Hypertension? / Edward D. FrohlichNewer Insights into the Biochemical Physiology of the Renin-Angiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12) / Carlos M. Ferrario, Jewell A. Jessup, and Jasmina Varagic -- Renin, Prorenin, and the (Pro)renin Receptor / Genevieve Nguyen and Aurelie Contrepas -- Intracellular Accumulation and Nuclear Trafficking of Angiotensin II and the Angiotensin II Type 1 Receptor / Julia L. Cook and Richard N. Re -- Pathophysiologic Implications of Cell Swelling in the Failing Heart: Influence of Intracrine and Extracellular Renin-Angiotensin Systems / Walmor C. De Mello -- Exploiting Rat Genetics to Investigate Hypertensive End-Organ Damage / Xiaoujun Liu, Christopher O.C. Bellamy, Linda J. Mullins, Donald Dunbar, and John J. Mullins -- Alternative Renin Transcripts and Functions of Cytoplasmatic Renin / Jörg Peters and Heike Wanka -- Novel Aspects of the Cardiac Renin-Angiotensin System / Vivek P. Singh, Kenneth M. Baker, and Rajesh Kumar -- Intracrine Function from Angiotensin to Stem Cells / Richard N. Re and Julia L. Cook -- Renin Cell Identity and Homeostasis / R. Ariel Gómez, Maria Luisa S. Sequeira Lopez, Xuan Jin, Magali Cordaillat, and Ellen Steward Pentz -- Role of Renal Aminopeptidases and Angiotensin Type-2 (AT2) Receptors in Sodium Excretion and Hypertension / Robert M. Carey, Shetal H. Padia, John J. Gildea, and Susanna R. Keller -- Intrarenal Angiotensin II Augmentation in Hypertension / Romer A. Gonzalez-Villalobos and L.G. Navar -- Collecting Duct Renin: A Critical Link in Angiotensin II-Dependent Hypertension / Minolfa C. Prieto and L. Gabriel Navar -- Renin-Angiotensin-Aldosterone System and Cardiomyocyte Apoptosis in Hypertensive Heart Disease / Arantxa González, Susana Ravassa, Begoña López, Javier Beaumonta, and Javier Díez -- Upregulation of Angiotensin II Type 2 Receptor (agtr2) Attenuates Atherosclerotic Lesion Formation and Enhances Apoptosis in the LDL Receptor Knockout Mice Fed High Cholesterol Diet / Jawahar L. Mehta, Magomed Khaidakov, Changping Hu, Giusto Spagnolli, and Dayuan Li -- Salt and Heart: RAAS Involvement / Jasmina Varagic and Carlos M. Ferrario -- Cardiac Effects of Aldosterone, the Bad, but Is There Also a Good? / Ludovic Bénard, Bernard Swynghedauw, Paul Milliez, Marie-Lory Ambroisine, Smail Messaoudi, Jane-Lise Samuel, and Claude Delcayre. |
| 520 | |a Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is produced, synthesized and indeed, present in many organisms including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the local cardiac renin-angiotensin aldosterone system.Cardiovascular, renal and hypertension oriented physicians, investigators and scientists would find this book of interest.Edward D. Frohlich, M.D., M.A.C.P, F.A.C.C., is the Alton Ochsner Distinguished Scientist at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans. He is past Editor-in-Chief of the American Heart Association journal HYPERTENSION.Richard N. Re, M.D., is the Section Head, Hypertension at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Ochsner's Scientific Director of Research. | ||
| 530 | |a Electronic reproduction; Available via World Wide Web | ||
| 533 | |a Online-Ausg. |d 2010 |n Electronic reproduction; Available via World Wide Web |7 |2010|||||||||| | ||
| 650 | 0 | |a Heart |x Physiology | |
| 650 | 0 | |a Renin-angiotensin system | |
| 650 | 2 | |a Receptors, Cell Surface |x physiology | |
| 650 | 2 | |a Hypertension |x metabolism | |
| 650 | 2 | |a Vacuolar Proton-Translocating ATPases |x metabolism | |
| 650 | 2 | |a Renin-Angiotensin System |x physiology | |
| 700 | 1 | |a Re, Richard N. |e eds |4 oth | |
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