Drug repurposing and computational drug discovery : strategies and advances / edited by Mithun Rudrapal, PhD
"This new volume presents exciting recent advances in drug repurposing and computational approaches for the discovery and development of drugs against certain difficult-to-treat and life-threatening diseases, including microbial infections, parasitic diseases, brain disorders, and cancer. Drug repurposing is defined as identifying new pharmacological indications from old, existing, failed, investigational, already marketed, or FDA approved drugs/pro-drugs, and the application of these newly developed drugs to the treatment of diseases other than the drug's original intended therapeutic use. The application of computational techniques in discovery research does not only help in the development of drugs from leads or existing drug molecules, but also can be of useful for the repurposing of existing drug candidates. This book is primarily aimed at delivering information on various computational techniques, tools, and databases being utilized for drug repurposing and for identifying the uses of existing drug candidates on different emerging or deadly diseases. With contributions from a global team of experts (academicians, scientists, and researchers), this volume, Drug Repurposing and Computational Drug Discovery: Strategies and Advances, explores the sophisticated tools and techniques of drug repurposing and computational drug discovery. It provides up-to-date and in-depth information on the state-of-the-art strategies and techniques being utilized for the discovery of therapeutic candidates from existing natural leads, synthetic compounds, and/or drug molecules by experimental (in vitro, in vivo) as well as computational (in silico) techniques. Drug repurposing and computational approaches addressed in the book target the discovery and development of drugs for microbial infections (bacterial, fungal, viral, COVID-19), parasitic diseases and neglected tropical diseases (NTDs), malignant diseases (cancer), inflammatory diseases, cardiovascular disorders, diabetes, and aging and neurological (CNS) disorders. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions."--.
| Medienart: |
E-Book |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
Palm Bay, FL, USA Burlington, ON, Canada: Apple Academic Press ; 2023 Boca Raton, FL, USA Abingdon, Oxon, UK: CRC Press ; 2023 |
| Ausgabe: |
First edition |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rudrapal, Mithun [HerausgeberIn] |
|---|
| Links: |
search.ebscohost.com [lizenzpflichtig] |
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| ISBN: |
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| Anmerkungen: |
Includes bibliographical references and index |
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| Umfang: |
1 Online-Ressource |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
1882621476 |
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| 245 | 1 | 0 | |a Drug repurposing and computational drug discovery |b strategies and advances |c edited by Mithun Rudrapal, PhD |
| 250 | |a First edition | ||
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| 264 | 1 | |a Palm Bay, FL, USA |a Burlington, ON, Canada |b Apple Academic Press |c 2023 | |
| 264 | 1 | |a Boca Raton, FL, USA |a Abingdon, Oxon, UK |b CRC Press |c 2023 | |
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| 500 | |a Includes bibliographical references and index | ||
| 505 | 8 | 0 | |a Drug Repurposing in Future Drug Discovery and Development / Kirti Agrawal, Malavika Saji, and Dhruv Kumar -- Approaches, Strategies, and Advances in Computational Drug Discovery and Drug Repurposing / Tripti Sharma, Ipsa Padhy, and Chita Ranjan Sahoo -- Drug Repurposing and Computational Drug Discovery for Viral Infections and Coronavirus Disease-2019 (COVID-19) / Siddhartha Maji, Vishnu Nayak Badavath, and Swastika Ganguly -- Drug Repurposing and Computational Drug Discovery for Parasitic Diseases and Neglected Tropical Diseases (NTDs) / James H. Zothantluanga, Arpita Paul, Abd. Kakhar Umar, and Dipak Chetia -- Drug Repurposing and Computational Drug Discovery for Malignant Diseases / Ashish Shah, Ghanshyam Parmar, and Ashish Patel -- Drug Repurposing and Computational Drug Discovery for Inflammatory Diseases / Vishal Kumar Singh, Himani Chaurasia, Jayati Dwivedi, Richa Mishra, and Ramendra K Singh -- Drug Repurposing and Computational Drug Discovery for Cardiovascular Disorders / Johra Khan and Mithun Rudrapal -- Drug Repurposing and Computational Drug Discovery for Diabetes / Manish Kumar Tripathi, Rahul Kumar Maurya, Alok Shiomurti Tripathi, and Mohammad Yasir -- Drug Repurposing and Computational Drug Discovery for Aging and Neurological Disorders / Kumar Nallasivan Palani, Karthikeyan Deivasigamani, Sivasubramanian Piramanayagam, and Vishali Murthy -- Challenges and Regulatory Issues in Drug Repurposing and Computational Drug Discovery / André M. Oliveira and Mithun Rudrapal. |
| 520 | |a "This new volume presents exciting recent advances in drug repurposing and computational approaches for the discovery and development of drugs against certain difficult-to-treat and life-threatening diseases, including microbial infections, parasitic diseases, brain disorders, and cancer. Drug repurposing is defined as identifying new pharmacological indications from old, existing, failed, investigational, already marketed, or FDA approved drugs/pro-drugs, and the application of these newly developed drugs to the treatment of diseases other than the drug's original intended therapeutic use. The application of computational techniques in discovery research does not only help in the development of drugs from leads or existing drug molecules, but also can be of useful for the repurposing of existing drug candidates. This book is primarily aimed at delivering information on various computational techniques, tools, and databases being utilized for drug repurposing and for identifying the uses of existing drug candidates on different emerging or deadly diseases. With contributions from a global team of experts (academicians, scientists, and researchers), this volume, Drug Repurposing and Computational Drug Discovery: Strategies and Advances, explores the sophisticated tools and techniques of drug repurposing and computational drug discovery. It provides up-to-date and in-depth information on the state-of-the-art strategies and techniques being utilized for the discovery of therapeutic candidates from existing natural leads, synthetic compounds, and/or drug molecules by experimental (in vitro, in vivo) as well as computational (in silico) techniques. Drug repurposing and computational approaches addressed in the book target the discovery and development of drugs for microbial infections (bacterial, fungal, viral, COVID-19), parasitic diseases and neglected tropical diseases (NTDs), malignant diseases (cancer), inflammatory diseases, cardiovascular disorders, diabetes, and aging and neurological (CNS) disorders. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions."-- | ||
| 650 | 0 | |a Drug development | |
| 650 | 0 | |a Drug development |x Data processing | |
| 650 | 0 | |a Therapeutics | |
| 650 | 2 | |a Drug Repositioning |x methods | |
| 650 | 2 | |a Drug Discovery |x methods | |
| 650 | 2 | |a Medical Informatics Computing | |
| 650 | 2 | |a Therapeutics | |
| 650 | 4 | |a Médicaments - Développement | |
| 650 | 4 | |a Médicaments - Développement - Informatique | |
| 650 | 4 | |a Thérapeutique | |
| 650 | 4 | |a treating (health care function) | |
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| 650 | 4 | |a SCIENCE / Biotechnology | |
| 650 | 4 | |a MEDICAL / Pharmacy | |
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| 650 | 4 | |a Therapeutics | |
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