Stem Cells : An Alternative Therapy for COVID-19 and Cytokine Storm
Front Cover -- Stem Cells -- Copyright Page -- Dedication -- Contents -- List of contributors -- Preface -- Introduction -- 1 Outbreak of novel disease -- 1 Targets of SARS-CoV-2: therapeutic implications for COVID-19 -- 1.1 Introduction -- 1.2 Human targets and pathogenicity of SARS-CoV and SARS-CoV-2 -- 1.2.1 ACE2 -- 1.2.1.1 Effect of ACE2 on various diseases -- 1.2.2 TMPRSS2 -- 1.2.3 Dipeptidyl peptidase 4 (DPP4) -- 1.3 Treatment of COVID-19 -- 1.3.1 Immunological role against SARS-CoV-2 and SARS-CoV -- 1.3.2 Suppression of the HCoV-229E virus by interferon (IFN) -- 1.3.3 Cold plasma treatment -- 1.3.4 Convalescent plasma therapy -- 1.3.5 Immune-modulating treatment -- 1.3.6 Low-dose radiation therapy -- 1.3.7 Mesenchymal stem cells in COVID-19 treatment -- 1.3.8 Potential vaccines -- 1.3.9 Monoclonal antibodies -- 1.3.10 Other treatments -- 1.4 Conclusion and future perspectives -- References -- 2 COVID-19 biology -- 2 COVID-19 biology: cytokine storms and their implications -- 2.1 Introduction -- 2.2 Cytokines and cytokine storm -- 2.3 COVID-19 disease and immunopathogenesis -- 2.4 Cytokine storms in COVID-19 -- 2.4.1 ILs -- 2.4.2 Interferons -- 2.4.3 Tumor necrosis factor-α -- 2.4.4 Colony-stimulating factors -- 2.4.5 Chemokines -- 2.5 Conclusion -- References -- 3 SARS-CoV-2 associated complications -- 3 Comparative clinical investigation of blood profiling in COVID-19 patients -- 3.1 Introduction -- 3.2 Comparative analysis of different physiological parameters in SARS-CoV-2 infection -- 3.2.1 Increase in neutrophils and loss of lymphocytes -- 3.2.2 Decrease in CD4/CD8-type regulatory lymphocyte cells -- 3.2.3 Increase in interleukin-6 and proinflammatory mediators -- 3.2.4 Increase in serum LDH, ALT, AST, CRP, D-dimer, hs-cTnI, ferritin, and other tissue-specific biomarkers..
Medienart: |
E-Book |
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Erscheinungsjahr: |
2023 ©2023 |
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Erschienen: |
San Diego: Elsevier Science & Technology ; 2023 ©2023 |
Ausgabe: |
1st ed. |
Sprache: |
Englisch |
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Beteiligte Personen: |
Verma, Yogesh Kumar [VerfasserIn] |
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Links: |
ebookcentral.proquest.com [lizenzpflichtig] |
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ISBN: |
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Anmerkungen: |
Description based on publisher supplied metadata and other sources |
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Umfang: |
1 online resource (437 pages) |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
1872365434 |
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