Antibody response following SARS-CoV-2 infection and implications for immunity : final update of a rapid, living review / Haley K. Holmer [and 6 others]

In January 2022, we published an evolving rapid review, meta-analysis, and data visualization that compared the risk of reinfection in adults with prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to the risk of infection in adults without a prior infection. We found that prior infection with the Alpha variant or the wild-type SARS-CoV-2 virus reduced the risk of another infection by 80–97 percent (pooled estimate 87%; 95% confidence interval [CI] 84–90%) compared with uninfected individuals in studies with a median followup of 8 months (range 4 to 13 months). Protection remained above 80 percent for at least 7 months. Our original review, published in March 2021,2 described the antibody response after infection with the SARS-CoV-2 virus, but found little information on the duration of the response beyond 6 months or on antibody formation in asymptomatic patients or in individuals who are immunocompromised..

Medienart:

E-Book

Erscheinungsjahr:

July 2022

Erschienen:

Rockville, Md.: Agency for Healthcare Research and Quality ; July 2022

Ausgabe:

Version 3.0.

Reihe:

Rapid evidence product

AHRQ pub - no. 22(23)-EHC037

Sprache:

Englisch

Beteiligte Personen:

Holmer, Haley K. [VerfasserIn]

Links:

www.ncbi.nlm.nih.gov [teilw. kostenfrei]

Themen:

Antibody Formation
COVID-19
COVID-19 Serological Testing
Immunologic Factors
Systematic Review

Anmerkungen:

Includes bibliographical references. - Description based on online resource; title from PDF title page (viewed March 9, 2023)

Umfang:

1 online resource (1 PDF file (40 pages)) ; illustrations.

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

1869385047