Characterization of myelin-specific autoantibodies in an EAE mouse model / vorgelegt von Leonard Hammermann

Abstract Autoimmune diseases are caused by an attack of the immune system against own tissues, but the exact effector mechanisms may vary between individual diseases and are not yet fully understood. The autoimmune disease multiple sclerosis (MS) is characterized by autoimmune damage of the myelin sheets in the central nervous system (CNS). There is a general consensus that the autoimmune process is mainly driven by encephalitogenic T cells, but the role of B cells in the pathogenesis of MS has also recently been appreciated. Previous work in our department has focused on the role of myelin....

Medienart:

E-Book

Erscheinungsjahr:

2023

Erschienen:

Göttingen: 2023

Sprache:

Deutsch

Beteiligte Personen:

Hammermann, Leonard [VerfasserIn]
Flügel, Alexander [Akademische/r BetreuerIn]
Stadelmann-Nessler, Christine [Akademische/r BetreuerIn]

Hochschulschrift:

Dissertation, Georg-August-Universität Göttingen, 2023

Links:

Volltext [kostenfrei]
Volltext [kostenfrei]

Themen:

8.18c5
Antibody
Autoantibody
EAE
FcγR
Hochschulschrift
IgA
IgD
IgE
IgG
IgM
Isotypes
MOG
Multiple Sclerosis

Umfang:

1 Online-Ressource ; Illustrationen, Diagramme

Weitere IDs:

urn:nbn:de:gbv:7-ediss-14897-3

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

1867564211