Emerging Drug Delivery and Biomedical Engineering Technologies : Transforming Therapy

This book highlights the advances in drug discovery and delivery and the need for emerging technologies. The text describes new micro and nanofabrication techniques, including methods like electrohydrodynamic processes, additive manufacturing, and microfluidics, which have potential to produce drug delivery systems that were not possible before..

Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Editor -- Contributors -- Chapter 1 Advances in Drug Delivery and the Need for Emerging Technologies -- 1.1 Introduction -- 1.2 Emerging Manufactured Therapeutics -- 1.2.1 Regenerative Medicine -- 1.2.2 3D Printing -- 1.2.3 3D and 4D Bioprinting -- 1.2.4 Electrospinning -- 1.3 Medical Devices and Assistants -- 1.3.1 Mobile Device Applications -- 1.3.2 Microneedles -- 1.3.3 Microfluidics (MFs) -- 1.3.4 Blockchain -- 1.4 Conclusions and Future Prospective -- References -- Chapter 2 Hot-Melt Extrusion: An Emerging Manufacturing Technology for Drug Products -- 2.1 General Introduction -- 2.2 A Brief Overview of Pharmaceutical HME Processing -- 2.3 Example Applications of Pharmaceutical HME -- 2.3.1 Drug-Enabled Formulations -- 2.3.1.1 Drug-Polymer Amorphous Solid Dispersions (ASDs) -- 2.3.1.2 Nano-Particulate Delivery Systems -- 2.3.1.3 Cocrystals and Salts -- 2.3.2 Controlled Release Drug Delivery Platforms -- 2.3.2.1 Sustained Delivery of Small Molecule Drugs -- 2.3.2.2 Implantable Devices for Delivery of Biologics -- 2.3.3 Continuous Processing - Extrusion Granulation -- 2.3.4 Patient-Centred Drug products -- 2.3.4.1 Fixed-Dose Combinations (FDCs) via Co-Extrusion -- 2.3.4.2 Fused Deposition Modelling 3D Printing -- 2.3.5 Abuse-Deterrent Formulations -- 2.4 HME and Continuous Manufacturing -- 2.4.1 Principle of Quality by Design (QbD) -- 2.4.2 Process Analytical Technology (PAT) Tools -- 2.4.2.1 Near- and Mid-Infrared Spectroscopy -- 2.4.2.2 Raman Spectroscopy -- 2.4.2.3 In-Line UV/Visible Spectroscopy -- 2.4.2.4 In-Process Rheometry -- 2.5 Summary and Future Perspectives -- References -- Chapter 3 3D Printing Technologies for Personalized Drug Delivery..

Medienart:	E-Book

Erscheinungsjahr:	2023 ©2023
Erschienen:	Milton: Taylor & Francis Group ; 2023 ©2023

Reihe:	Drugs and the Pharmaceutical Sciences Ser.

Sprache:	Englisch

Beteiligte Personen:	Lamprou, Dimitrios [HerausgeberIn]

Links:	ebookcentral.proquest.com [lizenzpflichtig]

ISBN:	978-1-000-85733-7 978-1-003-22446-4 978-1-000-85714-6

Themen:	Electronic books

Anmerkungen:	Description based on publisher supplied metadata and other sources

Umfang:	1 Online-Ressource (269 Seiten)

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1837524513