Essential Aspects of Immunometabolism in Health and Disease

Intro -- Preface -- Contents -- Contributors -- Overview of Immune Responses -- 1 General Aspects of the Immune System -- 2 Cells of the Immune System -- 3 Innate Immunity -- 4 Adaptive Immunity -- 4.1 Cell-Mediated Adaptive Immune Responses -- 4.2 Humoral Adaptive Immune Responses -- 5 Final Remarks -- References -- Metabolic Pathways and Cell Signaling -- 1 Overview of Metabolic Pathways -- 2 The Mechanistic Logic of Metabolic Signaling -- 3 Nutrient-Sensing Signaling Pathways -- 3.1 Lipid Sensing -- 3.2 Amino Acid Sensing -- 3.3 Carbohydrate Sensing -- 4 Extracellular Signals that Regulate Fuel Metabolism -- 5 Pathway Crosstalk in the Regulation of Metabolism -- References -- Mitochondrial Biogenesis and Dynamics in Health and Disease -- 1 Introduction -- 2 Mitochondrial Biogenesis -- 2.1 Transcription Factors Regulating Mitochondrial Biogenesis -- 2.2 The Role of Transcriptional Coactivators in Mitochondrial Biogenesis: PGC-1 Family -- 3 Mitochondrial Dynamics -- 3.1 Mitochondrial Fusion -- 3.2 Mitochondrial Fission -- 4 Mitochondrial Dynamics in Health and Disease -- 5 Concluding Remarks -- References -- Metabolic Pathways in Immune Cells Commitment and Fate -- 1 Introduction -- 2 Metabolic Pathway Impact on T Cell Differentiation and Function -- 3 Effector Versus Memory Cells -- 4 B Cell Metabolism -- 5 Macrophages M1/M2 -- 6 Dendritic Cells -- 7 Concluding Remarks -- References -- Metabolic Profile of Innate Immune Cells -- 1 Macrophages and Monocytes -- 1.1 M1 and M2 Subset Macrophages -- 1.2 Immunometabolism in Macrophages Effector Functions -- 2 Monocytes -- 3 Dendritic Cell Subsets -- 3.1 Bone-Marrow Dendritic Cells (BMDC) and Monocyte-Derived Dendritic Cells (MoDC) -- 3.2 Plasmacytoid Dendritic Cells (pDC) -- 3.3 Tolerogenic DC -- 4 Neutrophils -- 5 Other Granulocytes -- 6 Innate Lymphoid Cells..

Medienart:	E-Book

Erscheinungsjahr:	2021 ©2022
Erschienen:	Cham: Springer International Publishing AG ; 2021 ©2022

Sprache:	Englisch

Beteiligte Personen:	Camara, Niels Olsen Saraiva [VerfasserIn] Alves-Filho, Jose C. [Mitwirkende/r] Moraes-Vieira, Pedro Manoel Mendes de [Mitwirkende/r] Andrade-Oliveira, Vinicius [Mitwirkende/r]

Links:	ebookcentral.proquest.com [lizenzpflichtig]

ISBN:	978-3-030-86684-6

Themen:	Electronic books Immunology Metabolism

Anmerkungen:	Description based on publisher supplied metadata and other sources

Umfang:	1 online resource (285 pages)

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1821544978