Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans / submitted by Debbra Yasemin Knorr ; Reviewer: Prof. Dr. Ralf Heinrich, Second Reviewer: Prof. Dr. Gregor, Bucher
The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 cytokine receptors which also includes the classical erythropoietin receptor (EpoR). CRLF3 misregulation has been associated with several human diseases, but neither its ligand nor a particular function have been reported. Erythropoietin (Epo) is a vertebrate-specific helical cytokine that regulates erythropoiesis and activates cytoprotective pathways in various tissues incl....
| Medienart: |
Buch |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
Göttingen: 2022 |
| Weitere Ausgaben: |
Erscheint auch als Online-Ausgabe: Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Knorr, Debbra Yasemin, 1992- [VerfasserIn] |
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| Hochschulschrift: |
Dissertation, Georg-August-Universität Göttingen, 2022, Kumulative Dissertation |
| Umfang: |
138 Seiten ; Illustrationen, Diagramme |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
1807118487 |
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| 245 | 1 | 0 | |a Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans |c submitted by Debbra Yasemin Knorr ; Reviewer: Prof. Dr. Ralf Heinrich, Second Reviewer: Prof. Dr. Gregor, Bucher |
| 264 | 1 | |a Göttingen |c 2022 | |
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| 520 | |a The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 cytokine receptors which also includes the classical erythropoietin receptor (EpoR). CRLF3 misregulation has been associated with several human diseases, but neither its ligand nor a particular function have been reported. Erythropoietin (Epo) is a vertebrate-specific helical cytokine that regulates erythropoiesis and activates cytoprotective pathways in various tissues incl... | ||
| 650 | 4 | |a Neuroprotection | |
| 650 | 4 | |a Erythropoietin | |
| 650 | 4 | |a Epo | |
| 650 | 4 | |a CRLF3 | |
| 650 | 4 | |a Cytokine | |
| 650 | 4 | |a Hemolymph | |
| 650 | 4 | |a iPSC-derived neurons | |
| 650 | 4 | |a Acetylcholinesterase | |
| 650 | 4 | |a AChE | |
| 650 | 4 | |a Apoptosis | |
| 650 | 4 | |a Tribolium castaneum | |
| 650 | 4 | |a Locusta migratoria | |
| 650 | 4 | |a Epo-like ligand | |
| 650 | 4 | |a Neuroprotective hemolymph | |
| 650 | 4 | |a Ligand identification | |
| 650 | 4 | |a Insect | |
| 650 | 4 | |a Human | |
| 650 | 4 | |a Ace-1 | |
| 650 | 4 | |a Ace-2 | |
| 650 | 4 | |a Cytokine receptor like factor 3 | |
| 650 | 4 | |a Cell protection | |
| 650 | 4 | |a Anti-Apoptotic | |
| 650 | 4 | |a Cytoprotection | |
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