A one-two punch model for cancer therapy
Malignant cells are the result of mutations in genes controlling cell proliferation, invasion, and survival. Conventional chemotherapeutic drugs were designed to target vital cellular processes, such as DNA repair and replication, cytoskeleton structure, and cell division. These processes are also critical for normal proliferating cells, that as a consequence, such drugs are associated with unavoidable toxicities. Discoveries during the last decade have identified recurrent driver" mutations in some types of cancer. The cancer cells that harbor these genetic alterations.
| Medienart: |
E-Book |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
Erscheinungsort nicht ermittelbar: Utrecht University ; 2018 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, Liqin [VerfasserIn] |
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| Hochschulschrift: |
| Links: |
dspace.library.uu.nl [kostenfrei] |
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