Expression und Regulation von Renintranskripten durch Glukose- und Sauerstoffdepletion sowie den Zellzyklus in PC12 und mHippo18 Zellen / vorgelegt von: Annika Fischer ; 1. Gutachter: Prof. Dr. med. Jörg Peters, 2. Gutachter: Prof. Dr. med. Ulrich Wenzel
Differenzierung, Zellzyklus, Ischämie, Renin-Angiotensin-System, PC12 Zellen, mHippo18 Zellen.
Cerebral ischemia is one of the most common cardiovascular diseases and requires continuous improvement of medical prevention and therapy. The renin angiotensin aldosterone system (RAAS) might function as a potential therapeutic target, since angiotensin mediated processes such as fibrosis, necrosis and the development of reactive oxygen species contribute to cardiovascular and neurological diseases. The results of my dissertation suggest a potential relevance of intracellular RAAS as well as the alternative renin transcript Ren[1a-9] for further understanding of cerebral ischemia and resulting optimization of medical treatment and prevention..
| Medienart: |
E-Book |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
Greifswald: 2020 |
| Weitere Ausgaben: |
Erscheint auch als Druck-Ausgabe: Expression und Regulation von Renintranskripten durch Glukose- und Sauerstoffdepletion sowie den Zellzyklus in PC12 und mHippo18 Zellen |
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| Sprache: |
Deutsch |
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| Weiterer Titel: |
Glukosedepletion |
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| Beteiligte Personen: |
Fischer, Annika, 1995- [VerfasserIn] |
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| Hochschulschrift: |
Dissertation, Universitätsmedizin der Universität Greifswald, 2022 |
| Links: |
Volltext [kostenfrei] |
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| Themen: |
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| Anmerkungen: |
Literaturverzeichnis: Seite 93-102 |
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| Umfang: |
1 Online-Ressource (PDF-Datei: 104 Seiten, 16022 Kilobyte) ; Illustrationen (teilweise farbig), Diagramme (teilweise farbig) |
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| Weitere IDs: |
urn:nbn:de:gbv:9-opus-60248 |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Cerebral ischemia is one of the most common cardiovascular diseases and requires continuous improvement of medical prevention and therapy. The renin angiotensin aldosterone system (RAAS) might function as a potential therapeutic target, since angiotensin mediated processes such as fibrosis, necrosis and the development of reactive oxygen species contribute to cardiovascular and neurological diseases. The results of my dissertation suggest a potential relevance of intracellular RAAS as well as the alternative renin transcript Ren[1a-9] for further understanding of cerebral ischemia and resulting optimization of medical treatment and prevention. | ||
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