Human hypothalamus : anterior region / Edited by Dick F. Swaab, Felix Kreier, Paul J. Lucassen, Ahmad Salehi, Ruud M. Buijs

<B>SECTION 1 Introduction<br></b>1. Introduction: The anterior hypothalamus <br>2. History of hypothalamic research: "The spring of primitive existence#x94; <br>3. Anatomy and cytoarchitectonics of the human hypothalamus <br>4. Morphology and distribution of hypothalamic peptidergic systems <br>5. MRI maps, segregation, and white matter connectivity of the human hypothalamus in health <br>6. Magnetic resonance imaging of the hypothalamo-pituitary region <br>7. Resting-state functional connectivity of the human hypothalamus <br>8. Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology <br>9. Matching of the postmortem hypothalamus from patients and controls <br><b>SECTION 2 The basal forebrain cholinergic system</b><br>10. Spatial topography of the basal forebrain cholinergic projections: Organization and vulnerability to degeneration <br>11. The diagonal band of Broca in health and disease <br>12. Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease <br>13. Enlargement of early endosomes and traffic jam in basal forebrain cholinergic neurons in Alzheimer's disease <br>14. Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease<br><b>SECTION 3 The circadian system</b><br>15. The circadian system: From clocks to physiology <br>16. Development of the circadian system and relevance of periodic signals for neonatal development <br>17. Disrupted circadian rhythms and mental health <br>18. Diurnal and seasonal molecular rhythms in the human brain and their relation to Alzheimer disease <br>19. Circadian changes in Alzheimer's disease: Neurobiology, clinical problems, and therapeutic opportunities <br>20. The circadian system in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy <br>21. Retina and melanopsin neurons <br>22. Melatonin and the circadian system: Keys for health with a focus on sleep<br>23. Melatonin receptors, brain functions, and therapies <br>24. Chronotherapy <br>25. The use of melatonin to mitigate the adverse metabolic side effects of antipsychotics <br><b>SECTION 4 Bed nucleus of the stria terminalis and the fear circuit</b><br>26. Chemoarchitecture of the bed nucleus of the stria terminalis: Neurophenotypic diversity and function <br>27. Functional anatomy of the bed nucleus of the stria terminalis-hypothalamus neural circuitry: Implications for valence surveillance, addiction, feeding, and social behaviors <br>28. Roles of the bed nucleus of the stria terminalis and amygdala in fear reactions <br><b>SECTION 5 Preoptic area</b><br>29. The median preoptic nucleus: A major regulator of fluid, temperature, sleep, and cardiovascular homeostasis<br>30. The neuroendocrinology of the preoptic area in menopause: Symptoms and therapeutic strategies <br>31. The intermediate nucleus in humans: Cytoarchitecture, chemoarchitecture, and relation to sleep, sex, and Alzheimer disease.

Medienart:	E-Book

Erscheinungsjahr:	2021
Erschienen:	Amsterdam: Elsevier ; 2021

Reihe:	Handbook of clinical neurology - v. 179

Sprache:	Englisch

Weiterer Titel:	Anterior region

Beteiligte Personen:	Swaab, Dick Frans [Sonstige Person]

Links:	www.sciencedirect.com [lizenzpflichtig]

ISBN:	978-0-12-819976-3 0-12-819976-8

Themen:	Humans Hypothalamus Hypothalamus, Anterior R�egion hypothalamique ant�erieure

Umfang:	1 Online-Ressource

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PPN (Katalog-ID):	1793372632