Latent tuberculosis infection testing in people with compromised immunity prior to biologic therapy : a review of diagnostic accuracy, clinical utility, and guidelines / Calvin Young, Melissa Severn

There is no established gold standard technique for diagnosing latent TB infection. The most commonly used screening methods are the tuberculin skin test (TST) and interferon gamma release assays (IGRAs); however, these diagnostic tools have limited sensitivity and specificity. The objective of the current report is to evaluate the evidence regarding the diagnostic accuracy and clinical utility of the TST for patients with compromised immunity prior to initiating biologic treatment. Additionally, evidence-based guidelines regarding testing for latent TB infection in patients with compromised immunity prior to initiating biologic therapy will be reviewed. This report expands upon a previously completed CADTH report..

Medienart:

E-Book

Erscheinungsjahr:

December 1, 2020

Erschienen:

Ottawa: Canadian Agency for Drugs and Technologies in Health ; December 1, 2020

Reihe:

CADTH rapid response report: summary with critical appraisal

Sprache:

Englisch

Beteiligte Personen:

Young, Calvin [VerfasserIn]
Severn, Melissa [VerfasserIn]

Links:

www.ncbi.nlm.nih.gov [teilw. kostenfrei]

Themen:

Biological Therapy
Immunocompromised Host
Latent Tuberculosis
Practice Guidelines as Topic
Review

Anmerkungen:

Includes bibliographical references. - Description based on online resource; title from PDF title page (viewed September 7, 2021)

Umfang:

1 online resource (1 PDF file (47 pages)) ; illustration.

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

1776329066