Morphological and functional assessment of the uterus : "one-stop shop imaging" using a compressed-sensing accelerated, free-breathing T1-VIBE sequence / Daniel Hausmann, Diana Kreul, Markus Klarhöfer, Dominik Nickel, Robert Grimm, Berthold Kiefer, Philipp Riffel, Ulrike I. Attenberger, Frank G. Zöllner, Rahel A. Kubik-Huch

BACKGROUND: The combination of motion-insensitive, high-temporal, and spatial resolution imaging with evaluation of quantitative perfusion has the potential to increase the diagnostic capabilities of magnetic resonance imaging (MRI) in the female pelvis. - PURPOSE: To compare a free-breathing compressed-sensing VIBE (fbVIBE) with flexible temporal resolution (range = 4.6-13.8 s) with breath-hold VIBE (bhVIBE) and to evaluate the potential value of quantifying uterine perfusion. - MATERIAL AND METHODS: A total of 70 datasets from 60 patients (bhVIBE: n = 30; fbVIBE: n = 40) were evaluated by two radiologists. Only temporally resolved reconstruction (fbVIBE) was performed on 30 of the fbVIBE datasets. For a subset (n = 10) of the fbVIBE acquisitions, a time- and motion-resolved reconstruction (mrVIBE) was evaluated. Image quality (IQ), artifacts, diagnostic confidence (DC), and delineation of uterine structures (DoS) were graded on Likert scales (IQ/DC/DoS: 1 (non-diagnostic) to 5 (perfect); artifacts: 1 (no artifacts) to 5 (severe artifacts)). A Tofts model was applied for perfusion analysis. Ktrans was obtained in the myometrium (Mm), junctional zone (Jz), and cervix (Cx). - RESULTS: The median IQ/DoS/DC scores of fbVIBE (4/5/5 κ >0.7-0.9) and bhVIBE (4/4/4; κ = 0.5-0.7; P > 0.05) were high, but Artifacts were graded low (fbVIBE/bhVIBE: 2/2; κ = 0.6/0.5; P > 0.05). Artifacts were only slightly improved by the additional motion-resolved reconstruction (fbVIBE/mrVIBE: 2/1.5; P = 0.08); fbVIBE was preferred in most cases (7/10). Significant differences of Ktrans values were found between Cx, Jz, and Mm (0.12/0.21/0.19; P < 0.05). - CONCLUSION: The fbVIBE sequence allows functional and morphological assessment of the uterus at comparable IQ to bhVIBE..

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:62

Enthalten in:

Acta radiologica - 62(2021), 5, Seite 695-704

Sprache:

Englisch

Beteiligte Personen:

Hausmann, Daniel, 1981- [VerfasserIn]
Kreul, Diana, 1990- [VerfasserIn]
Klarhöfer, Markus [VerfasserIn]
Nickel, Marcel Dominik Johannes, 1979- [VerfasserIn]
Grimm, Robert [VerfasserIn]
Kiefer, Berthold [VerfasserIn]
Riffel, Philipp, 1982- [VerfasserIn]
Attenberger, Ulrike, 1980- [VerfasserIn]
Zöllner, Frank G., 1976- [VerfasserIn]
Kubik-Huch, Rahel A. [VerfasserIn]

Themen:

Adult
Artifacts
Cervix uteri
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Magnetic resonance imaging
Magnetic resonance perfusion
Middle Aged
Respiration
Uterine Diseases
Uterus

Anmerkungen:

Online veröffentlicht: June 29, 2020

Gesehen am 27.07.2021

Umfang:

10

doi:

10.1177/0284185120936260

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

1764616839