Mechanical properties of the composite material consisting of β-tcp and alginate-di-aldehyde-gelatin hydrogel and its degradation behavior / Michael Seidenstücker, Thomas Schmeichel, Lucas Ritschl, Johannes Vinke, Pia Schilling, Hagen Schmal, Anke Bernstein
Abstract: This work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive strength was determined using a Zwick Z005 universal testing machine. In addition, the degradation behavior according to ISO EN 10993-14 in TRIS buffer pH 5.0 and pH 7.4 over 60 days was determined, and its effects on the compressive strength were investigated. The loading was carried out by means of a flow-chamber. The weight of the samples (manufacturer: Robert Mathys Foundation (RMS) and Curasan) in TRIS solutions pH 5 and pH 7 increased within 4 h (mean 48 ± 32 mg) and then remained constant over the experimental period of 60 days. The determination surface roughness showed a decrease in the value for the ceramics incubated in TRIS compared to the untreated ceramics. In addition, an increase in protein concentration in solution was determined for ADA gelatin-loaded ceramics. The macroporous Curasan ceramic exhibited a maximum failure load of 29 ± 9.0 N, whereas the value for the microporous RMS ceramic was 931 ± 223 N. Filling the RMS ceramic with ADA gelatin increased the maximum failure load to 1114 ± 300 N. The Curasan ceramics were too fragile for loading. The maximum failure load decreased for the RMS ceramics to 686.55 ± 170 N by incubation in TRIS pH 7.4 and 651 ± 287 N at pH 5.0.
| Medienart: |
E-Book |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
Basel: MDPI ; 2021 Freiburg: Albert-Ludwigs-Universität Freiburg ; 2021 |
| Enthalten in: |
Materials - 14, 5 (2021), 1303 |
|---|
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Seidenstücker, Michael, 1976- [VerfasserIn] |
|---|
| Links: |
nbn-resolving.de [kostenfrei] |
|---|
| Umfang: |
1 Online-Ressource (18 Seiten) ; Illustrationen, Diagramme |
|---|
| doi: |
10.3390/ma14051303 |
|---|---|
| Weitere IDs: |
urn:nbn:de:bsz:25-freidok-1940175 FRUB-opus-194017 |
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
1761371754 |
|---|
| LEADER | 01000cam a2200265 4500 | ||
|---|---|---|---|
| 001 | 1761371754 | ||
| 003 | DE-627 | ||
| 005 | 20230426153125.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210628s2021 gw |||||o 00| ||eng c | ||
| 024 | 7 | |a urn:nbn:de:bsz:25-freidok-1940175 |2 urn | |
| 024 | 7 | |a 10.3390/ma14051303 |2 doi | |
| 024 | 8 | |a FRUB-opus-194017 |q Opus-Nr. | |
| 035 | |a (DE-627)1761371754 | ||
| 035 | |a (DE-599)KXP1761371754 | ||
| 035 | |a (OCoLC)1257787559 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 044 | |c XA-DE-BW | ||
| 082 | 0 | |a 617.69 |q DE-101 | |
| 082 | 0 | 4 | |a 610 |q DE-101 |
| 100 | 1 | |a Seidenstücker, Michael |d 1976- |e verfasserin |0 (DE-588)1078973113 |0 (DE-627)839988656 |0 (DE-576)452115086 |4 aut | |
| 245 | 1 | 0 | |a Mechanical properties of the composite material consisting of β-tcp and alginate-di-aldehyde-gelatin hydrogel and its degradation behavior |c Michael Seidenstücker, Thomas Schmeichel, Lucas Ritschl, Johannes Vinke, Pia Schilling, Hagen Schmal, Anke Bernstein |
| 264 | 1 | |a Basel |b MDPI |c 2021 | |
| 264 | 2 | |a Freiburg |b Albert-Ludwigs-Universität Freiburg |c 2021 | |
| 300 | |a 1 Online-Ressource (18 Seiten) |b Illustrationen, Diagramme | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Abstract: This work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive strength was determined using a Zwick Z005 universal testing machine. In addition, the degradation behavior according to ISO EN 10993-14 in TRIS buffer pH 5.0 and pH 7.4 over 60 days was determined, and its effects on the compressive strength were investigated. The loading was carried out by means of a flow-chamber. The weight of the samples (manufacturer: Robert Mathys Foundation (RMS) and Curasan) in TRIS solutions pH 5 and pH 7 increased within 4 h (mean 48 ± 32 mg) and then remained constant over the experimental period of 60 days. The determination surface roughness showed a decrease in the value for the ceramics incubated in TRIS compared to the untreated ceramics. In addition, an increase in protein concentration in solution was determined for ADA gelatin-loaded ceramics. The macroporous Curasan ceramic exhibited a maximum failure load of 29 ± 9.0 N, whereas the value for the microporous RMS ceramic was 931 ± 223 N. Filling the RMS ceramic with ADA gelatin increased the maximum failure load to 1114 ± 300 N. The Curasan ceramics were too fragile for loading. The maximum failure load decreased for the RMS ceramics to 686.55 ± 170 N by incubation in TRIS pH 7.4 and 651 ± 287 N at pH 5.0 | ||
| 700 | 1 | |a Schmeichel, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Ritschl, Lucas Maximilian |d 1987- |e verfasserin |0 (DE-588)1050833228 |0 (DE-627)785189440 |0 (DE-576)405222297 |4 aut | |
| 700 | 1 | |a Vinke, Johannes |e verfasserin |0 (DE-588)1019374799 |0 (DE-627)690873506 |0 (DE-576)357901487 |4 aut | |
| 700 | 1 | |a Schilling, Pia |e verfasserin |4 aut | |
| 700 | 1 | |a Schmal, Hagen |d 1969- |e verfasserin |0 (DE-588)121123049 |0 (DE-627)081101996 |0 (DE-576)292547986 |4 aut | |
| 700 | 1 | |a Bernstein, Anke |d 1961-2021 |e verfasserin |0 (DE-588)113061110 |0 (DE-627)691169942 |0 (DE-576)289750717 |4 aut | |
| 773 | 0 | 8 | |i Sonderdruck aus |t Materials |g 14, 5 (2021), 1303 |x 1996-1944 |
| 856 | 4 | 0 | |u https://nbn-resolving.de/urn:nbn:de:bsz:25-freidok-1940175 |q application/pdf |x Resolving-System |z kostenfrei |
| 856 | 4 | 0 | |u https://doi.org/10.3390/ma14051303 |v 2022-02-07 |x Resolving-System |z kostenfrei |
| 856 | 4 | 0 | |u https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-1940175 |v 2022-02-07 |x Resolving-System |
| 856 | 4 | 0 | |u https://d-nb.info/1229835229/34 |v 2022-02-07 |x Langzeitarchivierung Nationalbibliothek |
| 856 | 4 | 0 | |u https://freidok.uni-freiburg.de/data/194017 |q application/pdf |v 2022-02-07 |x Verlag |z kostenfrei |
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a ISIL_DE-25 | ||
| 912 | |a SYSFLAG_1 | ||
| 912 | |a GBV_KXP | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_2403 | ||
| 912 | |a ISIL_DE-LFER | ||
| 935 | |c so | ||
| 951 | |a BO | ||
| 953 | |2 045F |a 617.69 | ||
| 980 | |2 2003 |1 01 |x DE-25 |b 3941680811 |c 00 |f --%%-- |d --%%-- |e --%%-- |j --%%-- |k Elektronischer Volltext - Zugang über WWW |y l01 |z 28-06-21 | ||
| 980 | |2 2403 |1 01 |x DE-LFER |b 3946321704 |c 00 |f --%%-- |d --%%-- |e n |j --%%-- |y l01 |z 07-07-21 | ||
| 981 | |2 2003 |1 01 |x DE-25 |r http://nbn-resolving.de/urn:nbn:de:bsz:25-freidok-1940175 | ||
| 981 | |2 2403 |1 01 |x DE-LFER |r https://doi.org/10.3390/ma14051303 | ||
| 981 | |2 2403 |1 01 |x DE-LFER |r https://nbn-resolving.de/urn:nbn:de:bsz:25-freidok-1940175 | ||