Progress in the chemistry of organic natural products Volume 115
Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium..
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer..
| Medienart: |
Reihe |
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| Erscheinungsjahr: |
[2021] © 2021 |
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| Erschienen: |
Cham: Springer International Publishing ; 2021 © 2021 |
| Weitere Ausgaben: |
Erscheint auch als Online-Ausgabe: Progress in the Chemistry of Organic Natural Products 115 |
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| Enthalten in: |
Zur Gesamtaufnahme - Volume 115 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kinghorn, A. Douglas [HerausgeberIn] |
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| ISBN: |
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| Themen: |
Biochemistry. |
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| Umfang: |
vii, 203 Seiten |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
1759892777 |
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| 520 | |a Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium. | ||
| 520 | |a This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer. | ||
| 650 | 0 | |a Organic chemistry. | |
| 650 | 0 | |a Biochemistry. | |
| 650 | 0 | |a Medicinal chemistry. | |
| 650 | 0 | |a Chemistry. | |
| 650 | 0 | |a Plant science. | |
| 650 | 0 | |a Botany. | |
| 650 | 0 | |a Pharmaceutical technology. | |
| 700 | 1 | |a Kinghorn, A. Douglas |e herausgeberin |4 edt | |
| 700 | 1 | |a Falk, Heinz |e herausgeberin |4 edt | |
| 700 | 1 | |a Gibbons, Simon |e herausgeberin |4 edt | |
| 700 | 1 | |a Asakawa, Yoshinori |e herausgeberin |4 edt | |
| 700 | 1 | |a Liu, Ji-Kai |e herausgeberin |4 edt | |
| 700 | 1 | |a Dirsch, Verena M. |e herausgeberin |4 edt | |
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