Biotransformations in organic chemistry : a textbook / Kurt Faber
This, the sixth edition of the established textbook on biocatalysis, feeds into undergraduate and graduate courses in modern organic chemistry, as well being a concise introduction to the field. New material includes colour graphics and cutting-edge research..
Intro -- Preface -- References -- Contents -- Chapter 1: Introduction and Background Information -- 1.1 Introduction -- 1.2 Common Prejudices Against Enzymes -- 1.3 Advantages and Disadvantages of Biocatalysts -- 1.3.1 Advantages of Biocatalysts -- 1.3.2 Disadvantages of Biocatalysts -- 1.3.3 Isolated Enzymes Versus Whole Cell Systems -- 1.4 Enzyme Properties and Nomenclature -- 1.4.1 Structural Biology in a Nutshell -- 1.4.2 Mechanistic Aspects of Enzyme Catalysis -- 1.4.3 Classification and Nomenclature -- 1.4.4 Coenzymes -- 1.4.5 Enzyme Sources -- References -- Chapter 2: Biocatalytic Applications -- 2.1 Hydrolytic Reactions -- 2.1.1 Mechanistic and Kinetic Aspects -- 2.1.2 Hydrolysis of the Amide Bond -- 2.1.3 Ester Hydrolysis -- 2.1.3.1 Esterases and Proteases -- 2.1.3.2 Lipases -- 2.1.3.3 Hydrolysis of Lactones -- 2.1.4 Hydrolysis and Formation of Phosphate Esters -- 2.1.5 Hydrolysis of Epoxides -- 2.1.6 Hydrolysis of Nitriles -- 2.2 Reduction Reactions -- 2.2.1 Recycling of Cofactors -- 2.2.2 Reduction of Aldehydes and Ketones Using Isolated Enzymes -- 2.2.3 Reduction of Aldehydes and Ketones Using Whole Cells -- 2.2.4 Reduction of C=N Bonds -- 2.2.5 Reduction of C=C-Bonds -- 2.3 Oxidation Reactions -- 2.3.1 Oxidation of Alcohols and Aldehydes -- 2.3.2 Oxidation of Amines -- 2.3.3 Oxygenation Reactions -- 2.3.3.1 Hydroxylation of Alkanes -- 2.3.3.2 Hydroxylation of Aromatic Compounds -- 2.3.3.3 Epoxidation of Alkenes -- 2.3.3.4 Sulfoxidation Reactions -- 2.3.3.5 Baeyer-Villiger Reactions -- 2.3.3.6 Formation of Hydroperoxides -- 2.3.3.7 Dihydroxylation of Aromatic and Conjugated C=C Bonds -- 2.3.4 Peroxidation Reactions -- 2.4 Formation of Carbon-Carbon Bonds -- 2.4.1 Aldol Reactions -- 2.4.2 Thiamine-Dependent Acyloin and Benzoin Reactions -- 2.5 Addition and Elimination Reactions -- 2.5.1 Addition of Water -- 2.5.2 Addition of Ammonia..
Medienart: |
E-Book |
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Erscheinungsjahr: |
[2018] © 2018 |
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Erschienen: |
Cham: Springer ; 2018 © 2018 |
Ausgabe: |
Seventh extended and corrected edition |
Weitere Ausgaben: |
Erscheint auch als Druck-Ausgabe: Biotransformations in organic chemistry |
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Sprache: |
Englisch |
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Beteiligte Personen: |
Faber, Kurt, 1953- [VerfasserIn] |
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Links: |
ebookcentral.proquest.com [lizenzpflichtig] |
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ISBN: |
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BKL: |
35.52 / Präparative Organische Chemie |
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Themen: |
Biokonversion |
RVK: |
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Umfang: |
1 Online-Ressource (xi, 434 Seiten) ; Diagramme |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
1747863858 |
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520 | |a Intro -- Preface -- References -- Contents -- Chapter 1: Introduction and Background Information -- 1.1 Introduction -- 1.2 Common Prejudices Against Enzymes -- 1.3 Advantages and Disadvantages of Biocatalysts -- 1.3.1 Advantages of Biocatalysts -- 1.3.2 Disadvantages of Biocatalysts -- 1.3.3 Isolated Enzymes Versus Whole Cell Systems -- 1.4 Enzyme Properties and Nomenclature -- 1.4.1 Structural Biology in a Nutshell -- 1.4.2 Mechanistic Aspects of Enzyme Catalysis -- 1.4.3 Classification and Nomenclature -- 1.4.4 Coenzymes -- 1.4.5 Enzyme Sources -- References -- Chapter 2: Biocatalytic Applications -- 2.1 Hydrolytic Reactions -- 2.1.1 Mechanistic and Kinetic Aspects -- 2.1.2 Hydrolysis of the Amide Bond -- 2.1.3 Ester Hydrolysis -- 2.1.3.1 Esterases and Proteases -- 2.1.3.2 Lipases -- 2.1.3.3 Hydrolysis of Lactones -- 2.1.4 Hydrolysis and Formation of Phosphate Esters -- 2.1.5 Hydrolysis of Epoxides -- 2.1.6 Hydrolysis of Nitriles -- 2.2 Reduction Reactions -- 2.2.1 Recycling of Cofactors -- 2.2.2 Reduction of Aldehydes and Ketones Using Isolated Enzymes -- 2.2.3 Reduction of Aldehydes and Ketones Using Whole Cells -- 2.2.4 Reduction of C=N Bonds -- 2.2.5 Reduction of C=C-Bonds -- 2.3 Oxidation Reactions -- 2.3.1 Oxidation of Alcohols and Aldehydes -- 2.3.2 Oxidation of Amines -- 2.3.3 Oxygenation Reactions -- 2.3.3.1 Hydroxylation of Alkanes -- 2.3.3.2 Hydroxylation of Aromatic Compounds -- 2.3.3.3 Epoxidation of Alkenes -- 2.3.3.4 Sulfoxidation Reactions -- 2.3.3.5 Baeyer-Villiger Reactions -- 2.3.3.6 Formation of Hydroperoxides -- 2.3.3.7 Dihydroxylation of Aromatic and Conjugated C=C Bonds -- 2.3.4 Peroxidation Reactions -- 2.4 Formation of Carbon-Carbon Bonds -- 2.4.1 Aldol Reactions -- 2.4.2 Thiamine-Dependent Acyloin and Benzoin Reactions -- 2.5 Addition and Elimination Reactions -- 2.5.1 Addition of Water -- 2.5.2 Addition of Ammonia. | ||
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