Endothelial Signaling in Vascular Dysfunction and Disease : From Bench to Bedside

Front Cover -- Endothelial Signaling in Vascular Dysfunction and Disease -- Copyright Page -- Dedication -- Contents -- List of contributors -- Preface -- 1 The vascular tree as an integrative structure -- 1 The vascular system: components, signaling, and regulation -- 1.1 Introduction -- 1.2 Components of the vascular tree -- 1.2.1 Arteries, veins, and lymphatic system -- 1.2.2 The endothelium -- 1.2.3 The basement matrix -- 1.2.4 Smooth muscle -- 1.2.5 Macrovascular and microvascular vessels -- 1.3 Endothelial signaling -- 1.3.1 Mechanotransduction -- 1.3.2 Chemotransduction -- 1.3.3 Biochemical signals associated with mechano and chemotransduction -- 1.3.3.1 Reactive oxygen species and nitric oxide -- 1.3.3.2 Growth factors -- 1.3.3.3 Calcium signaling -- 1.4 Regulation of vascular homeostasis: healthy and diseased systems -- 1.4.1 Inflammation signaling -- 1.4.2 Angiogenic signaling -- 1.4.3 Endothelial cell polarization -- 1.4.4 Barrier function -- 1.5 The endothelium in innate and adaptive immunity -- 1.6 Vascular signals in progression of disease -- 1.7 Conclusion -- References -- 2 Endothelial signaling in inflammatory diseases -- 2 Reactive oxygen species-induced reactive oxygen species release in vascular signaling and disease -- 2.1 Introduction -- 2.2 Reactive oxygen species -- 2.3 Double-edged role of reactive oxygen species -- 2.3.1 Beneficial reactive oxygen species effects: essential roles in physiology -- 2.3.2 Harmful reactive oxygen species effects: roles in pathology and disease -- 2.4 Source of reactive oxygen species -- 2.4.1 Nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species -- 2.4.2 Mitochondrial reactive oxygen species -- 2.5 Reactive oxygen species-induced reactive oxygen species release -- 2.6 Reactive oxygen species-induced reactive oxygen species release in cardiovascular disease..

Medienart:	E-Book

Erscheinungsjahr:	2021 ©2021
Erschienen:	San Diego: Elsevier Science & Technology ; 2021 ©2021

Sprache:	Englisch

Beteiligte Personen:	Chatterjee, Shampa [VerfasserIn]

Links:	ebookcentral.proquest.com [lizenzpflichtig] Inhaltsverzeichnis

ISBN:	978-0-12-816382-5

Themen:	Blood-vessels-Diseases Electronic books

Anmerkungen:	Description based on publisher supplied metadata and other sources

Umfang:	1 online resource (279 pages)

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1746037539