Details der Publikation - Risk factors for the development of postoperative delirium in pediatric intensive care patients

Risk factors for the development of postoperative delirium in pediatric intensive care patients / Jochen Meyburg, Mona-Lisa Dill, Rebecca von Haken, Susanne Picardi, Jens Hendrik Westhoff, Gabrielle Silver, Chani Traube

OBJECTIVES: To determine and quantify risk factors for postoperative pediatric delirium. - DESIGN: Single-center prospective cohort study. - SETTING: Twenty-two bed PICU in a tertiary care academic medical center in Germany. - PATIENTS: All children admitted after major elective surgery (n = 93; 0-17 yr). - INTERVENTIONS: After awakening, children were screened for delirium using the Cornell Assessment of Pediatric Delirium bid over a period of 5 days. Demographic and clinical data were collected from the initiation of general anesthesia. - MEASUREMENTS AND MAIN RESULTS: A total of 61 patients (66%) were delirious. Younger children developed delirium more frequently, and the symptoms were more pronounced. The number of preceding operations did not influence the risk of delirium. Total IV anesthesia had a lower risk than inhalational anesthesia (p < 0.05). Duration of anesthesia was similar in all groups. Patients with delirium had a longer duration of mechanical ventilation in the PICU (p < 0.001). Significant differences in cumulative doses of various medications (e.g., sedatives, analgesics, and anticholinergics) were noted between groups; these differences were independent of disease severity. Invasive catheters and respiratory devices (p < 0.01) as well as infections (p < 0.001) increased risk of delirium. - CONCLUSIONS: A high prevalence of delirium was noted in the PICU, and several perioperative risk factors were identified. Our data may be a base for development of strategies to prevent and treat postoperative delirium in children..

Medienart:	E-Artikel

Erscheinungsjahr:	2018
Erschienen:	2018

Enthalten in:	Zur Gesamtaufnahme - volume:19
Enthalten in:	Pediatric critical care medicine - 19(2018), 10, Seite e514-e521

Sprache:	Englisch

Beteiligte Personen:	Meyburg, Jochen, 1968- [VerfasserIn] Ritsert, Mona-Lisa, 1989- [VerfasserIn] Haken, Rebecca von, 1967- [VerfasserIn] Picardi, Susanne, 1976- [VerfasserIn] Westhoff, Jens, 1976- [VerfasserIn] Silver, Gabrielle [VerfasserIn] Traube, Chani [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

Themen:	Age Factors Anesthesia, Inhalation Anesthesia, Intravenous Case-Control Studies Child Child, Preschool Dose-Response Relationship, Drug Emergence Delirium Female Humans Infant Intensive Care Units, Pediatric Male Prevalence Prospective Studies Risk Factors Severity of Illness Index Time Factors

Anmerkungen:	Gesehen am 08.04.2020

Umfang:	8

doi:	10.1097/PCC.0000000000001681

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	169425108X

Internformat


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245	1	0	\|a Risk factors for the development of postoperative delirium in pediatric intensive care patients \|c Jochen Meyburg, Mona-Lisa Dill, Rebecca von Haken, Susanne Picardi, Jens Hendrik Westhoff, Gabrielle Silver, Chani Traube
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Risk factors for the development of postoperative delirium in pediatric intensive care patients / Jochen Meyburg, Mona-Lisa Dill, Rebecca von Haken, Susanne Picardi, Jens Hendrik Westhoff, Gabrielle Silver, Chani Traube

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