Details der Publikation - Practical recommendations for fertility preservation in women by the FertiPROTEKT network

Practical recommendations for fertility preservation in women by the FertiPROTEKT network : Part II: fertility preservation techniques / Michael von Wolff, A. Germeyer, J. Liebenthron, M. Korell, F. Nawroth

PURPOSE: In addition to guidelines focusing on scientific evidence, practical recommendations on fertility preservation are also needed. - METHODS: A selective literature search was performed based on the clinical and scientific experience of the authors. This article (Part II) focuses on fertility preservation techniques. Part I, also published in this journal, provides information on disease prognosis, disease-specific therapy, and risks for loss of fertility. - RESULTS: Ovarian stimulation including double stimulation and freezing of oocytes is the best-established therapy providing live birth chances in women < 35 years with high ovarian reserve of around 30-40%. Ovarian tissue freezing is especially useful in young women with good ovarian, if spontaneous conception is favoured and if < 1 week until chemotherapy is provided. Data on success rates are still limited, but this further evolving technique will possibly reach similar success rates as ovarian stimulation. GnRH agonists seem to reduce the risk of premature ovarian failure up to 50%; however, the effect is possibly not long-lasting. Ovarian transposition can easily be combined with freezing of ovarian tissue and is the preferred technique before pelvic radiotherapy. Other techniques, such as in vitro maturation, are limited to women with high ovarian reserve and remain less effective. In addition, procedures such as in vitro growth of follicles, etc. are still experimental. - CONCLUSIONS: Fertility preservation in women provides realistic chances of becoming pregnant. The choice of technique needs to be based on the time required, the woman's age, its risks and efficacy, and the individual preference of the patient..

Medienart:	E-Artikel

Erscheinungsjahr:	2018
Erschienen:	2018

Enthalten in:	Zur Gesamtaufnahme - volume:297
Enthalten in:	Archives of gynecology and obstetrics - 297(2018), 1, Seite 257-267

Sprache:	Englisch

Beteiligte Personen:	Wolff, Michael von, 1966- [VerfasserIn] Germeyer, Ariane, 1973- [VerfasserIn]

Links:	Volltext

Themen:	Adult Female Fertility Preservation Fertility preservation GnRH agonists Humans Oocyte ovarian stimulation Ovarian tissue Ovulation Induction Prospective Studies Young Adult

Anmerkungen:	First online: 27 November 2017 Gesehen am 09.04.2019

Umfang:	11

doi:	10.1007/s00404-017-4595-2

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1663002304

Internformat


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245	1	0	\|a Practical recommendations for fertility preservation in women by the FertiPROTEKT network \|b Part II: fertility preservation techniques \|c Michael von Wolff, A. Germeyer, J. Liebenthron, M. Korell, F. Nawroth
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Practical recommendations for fertility preservation in women by the FertiPROTEKT network : Part II: fertility preservation techniques / Michael von Wolff, A. Germeyer, J. Liebenthron, M. Korell, F. Nawroth

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