DJ-1/PARK7 Protein : Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases / edited by Hiroyoshi Ariga, Sanae M. M. Iguchi-Ariga
This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson’s disease (PD), park7. The DJ-1 gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of DJ-1, and explains the history and research development to understand the following chapters. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader will discover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases..
Preface.- Chapter 1 Introduction/Overview -- Chapter 2 Structural Biology of the DJ-1 Superfamily -- Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases -- Chapter 4 DJ-1 as an oncogene and its clinical significance -- Chapter 5 Role of DJ-1 in fertilization -- Chapter 6 Anti-oxidative stress function of DJ-1 -- Chapter 7 Ttranscriptional regulation of DJ-1 -- Chapter 8 Regulation of Signal Transduction by DJ-1 -- Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal -- Chapter 10 DJ-1 as a biomarker of Parkinson's disease -- Chapter 11 Roles of DJ-1 in diabetes mellitus -- Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases -- Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy..
| Medienart: |
E-Book |
|---|
| Erscheinungsjahr: |
2017 |
|---|---|
| Erschienen: |
Singapore: Springer ; 2017 |
| Reihe: |
|---|
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Ariga, Hiroyoshi [HerausgeberIn] |
|---|
| Links: |
|---|
| ISBN: |
|---|
| Nlm: |
QU 55 |
|---|---|
| Themen: |
Biochemistry |
| Umfang: |
Online-Ressource (VIII, 222 p. 78 illus., 46 illus. in color, online resource) |
|---|
| doi: |
10.1007/978-981-10-6583-5 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
1657203093 |
|---|
| LEADER | 01000cam a22002652 4500 | ||
|---|---|---|---|
| 001 | 1657203093 | ||
| 003 | DE-627 | ||
| 005 | 20240322113522.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 171204s2017 si |||||o 00| ||eng c | ||
| 020 | |a 9789811065835 |9 978-981-10-6583-5 | ||
| 024 | 7 | |a 10.1007/978-981-10-6583-5 |2 doi | |
| 035 | |a (DE-627)1657203093 | ||
| 035 | |a (DE-576)495982709 | ||
| 035 | |a (DE-599)BSZ495982709 | ||
| 035 | |a (OCoLC)1018235633 | ||
| 035 | |a (DE-He213)978-981-10-6583-5 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 044 | |c XB-SG | ||
| 050 | 0 | |a RC261-271 | |
| 060 | 0 | |a QU 55 | |
| 072 | 7 | |a MJCL |2 bicssc | |
| 072 | 7 | |a MED062000 |2 bisacsh | |
| 245 | 1 | 0 | |a DJ-1/PARK7 Protein |b Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases |c edited by Hiroyoshi Ariga, Sanae M. M. Iguchi-Ariga |
| 264 | 1 | |a Singapore |b Springer |c 2017 | |
| 300 | |a Online-Ressource (VIII, 222 p. 78 illus., 46 illus. in color, online resource) | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Advances in Experimental Medicine and Biology |v 1037 | |
| 490 | 0 | |a SpringerLink |a Bücher | |
| 490 | 0 | |a Springer eBook Collection |a Biomedical and Life Sciences | |
| 520 | |a This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson’s disease (PD), park7. The DJ-1 gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of DJ-1, and explains the history and research development to understand the following chapters. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader will discover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases. | ||
| 520 | |a Preface.- Chapter 1 Introduction/Overview -- Chapter 2 Structural Biology of the DJ-1 Superfamily -- Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases -- Chapter 4 DJ-1 as an oncogene and its clinical significance -- Chapter 5 Role of DJ-1 in fertilization -- Chapter 6 Anti-oxidative stress function of DJ-1 -- Chapter 7 Ttranscriptional regulation of DJ-1 -- Chapter 8 Regulation of Signal Transduction by DJ-1 -- Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal -- Chapter 10 DJ-1 as a biomarker of Parkinson's disease -- Chapter 11 Roles of DJ-1 in diabetes mellitus -- Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases -- Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy. | ||
| 650 | 0 | |a Medicine | |
| 650 | 0 | |a Cancer research | |
| 650 | 0 | |a Neurosciences | |
| 650 | 0 | |a Biochemistry | |
| 650 | 0 | |a Cell biology | |
| 650 | 0 | |a Biomedicine | |
| 650 | 2 | |a Parkinson Disease Associated Proteins |x chemistry | |
| 650 | 2 | |a Neurodegenerative Diseases |x genetics | |
| 650 | 2 | |a Neoplasms |x genetics | |
| 650 | 2 | |a Oxidative Stress |x drug effects | |
| 700 | 1 | |a Ariga, Hiroyoshi |e hrsg |4 edt | |
| 700 | 1 | |a Iguchi-Ariga, Sanae M. M. |e hrsg |4 edt | |
| 776 | 1 | |z 9789811065828 | |
| 776 | 0 | 8 | |i Druckausg. |z 978-981-10-6582-8 |
| 776 | 0 | 8 | |i Printed edition |z 9789811065828 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-981-10-6583-5 |m B:SPRINGER |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 2 | |u https://swbplus.bsz-bw.de/bsz495982709cov.jpg |m V:DE-576 |m X:springer |q image/jpeg |v 20180119134952 |3 Cover |
| 889 | |w (DE-627)1006716971 | ||
| 912 | |a ZDB-2-SBL |b 2017 | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a ISIL_DE-84 | ||
| 912 | |a SYSFLAG_1 | ||
| 912 | |a GBV_KXP | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a ISIL_DE-18 | ||
| 912 | |a GBV_ILN_22_i06404 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a ISIL_DE-3 | ||
| 912 | |a GBV_ILN_100 | ||
| 912 | |a ISIL_DE-Ma9 | ||
| 912 | |a GBV_ILN_101 | ||
| 912 | |a ISIL_DE-Ma14 | ||
| 912 | |a GBV_ILN_118 | ||
| 912 | |a ISIL_DE-Kt1 | ||
| 912 | |a GBV_ILN_120 | ||
| 912 | |a ISIL_DE-715 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a ISIL_DE-25 | ||
| 912 | |a GBV_ILN_2006 | ||
| 912 | |a ISIL_DE-14 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a ISIL_DE-90 | ||
| 912 | |a GBV_ILN_2015 | ||
| 912 | |a ISIL_DE-93 | ||
| 912 | |a GBV_ILN_2017 | ||
| 912 | |a ISIL_DE-576 | ||
| 951 | |a BO | ||
| 953 | |2 045F |a 614.5999 | ||
| 980 | |2 20 |1 01 |x 0084 |b 4158674921 |h CATDESC_SPR-EB |u CATDESC_SPR-EB |y z |z 29-06-22 | ||
| 980 | |2 22 |1 01 |x 0018 |b 1726790223 |c 00 |f --%%-- |d --%%-- |e s |j --%%-- |h h64 Springer Biomedical |k Campuslizenz Universität Hamburg. - Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden durch Robots. |y zi06404 |z 05-12-17 | ||
| 980 | |2 65 |1 01 |x 0003 |b 1831213656 |c 03 |f --%%-- |d ebook |e --%%-- |j --%%-- |h OLR-SEB-ZDB-2-SBL |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. |y k3o |z 08-12-18 | ||
| 980 | |2 100 |1 01 |x 3100 |b 1736809741 |c 00 |f --%%-- |d --%%-- |e s |j --%%-- |c 09 |f --%%-- |d eBook Springer |e --%%-- |j --%%-- |h OLR-SEB |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden durch Robots. |y z |z 24-12-17 | ||
| 980 | |2 101 |1 01 |x 3101 |b 1736839977 |c 00 |f --%%-- |d --%%-- |e s |j --%%-- |c 09 |f --%%-- |d eBook Springer |e --%%-- |j --%%-- |h OLR-SEB |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden durch Robots. |y z |z 24-12-17 | ||
| 980 | |2 118 |1 01 |x 3329 |b 1726765512 |h OLR-SEB |k Campusweiter Zugriff HSA - Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden durch Robots. |y z1 |z 05-12-17 | ||
| 980 | |2 120 |1 01 |x 0715 |b 1726932966 |h OLR-ESP |k Campusweiter Zugriff (Universität Oldenburg). - Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden. |y z |z 05-12-17 | ||
| 980 | |2 120 |1 02 |x 0715 |b 4185224435 |c 00 |f --%%-- |d --%%-- |e g |j --%%-- |h alma |y z |z 07-09-22 | ||
| 980 | |2 2003 |1 01 |x DE-25 |b 3393632833 |c 00 |f --%%-- |d --%%-- |e --%%-- |j n |k Elektronischer Volltext - Universitätslizenz |y l01 |z 16-11-17 | ||
| 980 | |2 2006 |1 01 |x DE-14 |b 3393632884 |c 00 |f --%%-- |d --%%-- |e --%%-- |j --%%-- |y l01 |z 16-11-17 | ||
| 980 | |2 2014 |1 01 |x DE-90 |b 3393632930 |c 00 |f --%%-- |d --%%-- |e --%%-- |j kp |y l01 |z 16-11-17 | ||
| 980 | |2 2014 |1 02 |x DE-90 |b 3393632949 |c 00 |f --%%-- |d --%%-- |e --%%-- |j kp |y l02 |z 16-11-17 | ||
| 980 | |2 2015 |1 01 |x DE-93 |b 339363299X |c 00 |f --%%-- |d --%%-- |e p |j --%%-- |k Campuslizenz |y l01 |z 16-11-17 | ||
| 980 | |2 2017 |1 01 |x DE-576 |b 3393633058 |c 00 |f --%%-- |d --%%-- |e --%%-- |j n |k Besitznachweis BSZ nur für Dateneinspielung, keine echte Lizenz vorhanden |y l01 |z 16-11-17 | ||
| 981 | |2 20 |1 01 |x 0084 |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 22 |1 01 |x 0018 |y Volltextzugang |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 22 |1 01 |x 0018 |y Nur für Angehörige der Universität Hamburg: Volltextzugang von außerhalb des Campus |r http://emedien.sub.uni-hamburg.de/han/SpringerEbooksUKE/doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 65 |1 01 |x 0003 |y Volltextzugang Campus |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 100 |1 01 |x 3100 |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 100 |1 01 |x 3100 |y für Uniangehörige: Zugang weltweit |r https://han.med.uni-magdeburg.de/han/SPR-eBook-BiomedicalandLifeScience-einzeln/doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 101 |1 01 |x 3101 |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 101 |1 01 |x 3101 |y für Uniangehörige: Zugang weltweit |r https://han.med.uni-magdeburg.de/han/SPR-eBook-BiomedicalandLifeScience-einzeln/doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 118 |1 01 |x 3329 |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 120 |1 01 |x 0715 |r https://doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 120 |1 02 |x 0715 |r http://49gbv-uob-primo.hosted.exlibrisgroup.com/openurl/49GBV_UOB/UOB_services_page?u.ignore_date_coverage=true&rft.mms_id=991015280158803501 | ||
| 981 | |2 2003 |1 01 |x DE-25 |r http://www.redi-bw.de/start/unifr/EBooks-springer/10.1007/978-981-10-6583-5 | ||
| 981 | |2 2006 |1 01 |x DE-14 |r http://dx.doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 2014 |1 01 |x DE-90 |y Zugang im Netz des KIT |r http://dx.doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 2014 |1 02 |x DE-90 |y Zugang im Netz der HKA |r http://dx.doi.org/10.1007/978-981-10-6583-5 | ||
| 981 | |2 2015 |1 01 |x DE-93 |r http://dx.doi.org/10.1007/978-981-10-6583-5 | ||
| 983 | |2 120 |1 00 |x DE-715 |8 99 |a ww | ||
| 985 | |2 22 |1 01 |x 0018 |a h64 ebook | ||
| 985 | |2 120 |1 01 |x 0715 |a YH 1694 | ||
| 995 | |2 20 |1 01 |x 0084 |a CATDESC_SPR-EB | ||
| 995 | |2 22 |1 01 |x 0018 |a h64 Springer Biomedical | ||
| 995 | |2 65 |1 01 |x 0003 |a OLR-SEB-ZDB-2-SBL | ||
| 995 | |2 100 |1 01 |x 3100 |a OLR-SEB | ||
| 995 | |2 101 |1 01 |x 3101 |a OLR-SEB | ||
| 995 | |2 118 |1 01 |x 3329 |a OLR-SEB | ||
| 995 | |2 120 |1 01 |x 0715 |a OLR-ESP | ||
| 995 | |2 120 |1 02 |x 0715 |a alma | ||
| 998 | |2 2003 |1 01 |x DE-25 |0 04-12-17 |f 17 | ||