Details der Publikation - Autophagy and Cancer

Autophagy and Cancer / edited by Hong-Gang Wang

This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction regulation of autophagy. The next chapters deal with the complex relationship between autophagy and tumorigenesis through in-depth discussions of how autophagy influences cell survival, apoptosis, inflammation, immunity, tumor microenvironment, metabolic stress, DNA damage, and genomic instability. The remaining chapters discuss how autophagy affects cancer cell response to therapy and how to best modulate autophagy for therapeutic benefit - what to target and how to target. We hope that this monograph will be an invaluable reference source for professionals, students, postdoctoral fellows, and senior scientists working in the fields of autophagy and cancer.

Medienart:	E-Book

Erscheinungsjahr:	2013
Erschienen:	New York, NY: Springer ; 2013

Weitere Ausgaben:	Druckausg.: Autophagy and cancer

Reihe:	Current Cancer Research - 8 SpringerLink, Bücher

Sprache:	Englisch

Beteiligte Personen:	Wang, Hong-Gang [VerfasserIn]

Links:	Volltext Volltext [lizenzpflichtig]

ISBN:	978-1-4614-6561-4

Nlm:	QZ 200
Themen:	Autophagie Autophagy Biomedicine Cancer Carcinogenesis Cytology Human physiology Krebs Medicine Neoplasms Oncology

RVK:	RVK Klassifikation XH 1813

Anmerkungen:	Includes index

Umfang:	Online-Ressource (XI, 261 p. 33 illus., 29 illus. in color, digital)

doi:	10.1007/978-1-4614-6561-4

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1652259945

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505	8	0	\|a Preface -- Historical Overview of Autophagy -- The Core Molecular Machinery of Autophagosome Formation -- The origin of autophagosomes: The beginning of an end -- Signal Transduction Regulation of Autophagy -- Role of Autophagy in Tumorigenesis -- Selective autophagy and cancer -- Oncogenes and tumor suppressor genes in autophagy -- Autophagy and Immunity -- Autophagy and the Tumor Microenvironment -- Autophagy and Cancer Therapy -- The Crosstalk between Apoptosis & Autophagy -- Autophagy and Cancer Drug Discovery -- Index.
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Autophagy and Cancer / edited by Hong-Gang Wang

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