Details der Publikation - Impact on image quality and radiation dose of third-generation dual-source computed tomography of the coronary arteries

Impact on image quality and radiation dose of third-generation dual-source computed tomography of the coronary arteries / Georg Apfaltrer, Dieter H. Szolar, Eric Wurzinger, Richard A. P. Takx, John W. Nance, Anja Dutschke, Sebastian Tschauner, Christian Loewe, Helmut Ringl, Erich Sorantin, and Paul Apfaltrer

The aim of this study was to assess the image quality (IQ) and radiation dose of third-generation dual-source computed tomography (CT) coronary angiography (cCTA) in comparison with 64-slice single-source CT. This retrospective study included 140 patients (73 men, mean age 62 ± 11 years) with low-to-intermediate probability of coronary artery disease who underwent either third-generation dual-source cCTA using prospectively electrocardiography-triggered high-pitch spiral acquisition (n = 70) (group 1) or retrospective electrocardiography-gated cCTA on a 64-slice CT system (n = 70) (group 2). Contrast-to-noise and signal-to-noise ratios were measured within the aorta and coronary arteries. Subjective IQ was assessed using a 5-point Likert scale. Effective dose was estimated using specific conversion factors. The contrast-to-noise ratio of group 1 was significantly higher than group 2 at all levels (all p <0.001). Signal-to-noise ratio of group 1 was also significantly higher than group 2 (p <0.05), except for the distal left circumflex artery. Subjective IQ for group 1 was rated significantly better than for group 2 (median score [25th to 75th percentile]: 1 [1 to 2] vs 2 [2 to 3]; p <0.001). The median effective dose was 1.55 mSv (1.09 to 1.88) in group 1 versus 12.29 mSv (11.63 to 14.36) in group 2 (p <0.001) which corresponds to a mean radiation dose reduction of 87.4%. In conclusion, implementation of third-generation dual-source CT system for cCTA leads to improved IQ with significant radiation dose savings..

Medienart:	E-Artikel

Erscheinungsjahr:	2017
Erschienen:	2017

Enthalten in:	Zur Gesamtaufnahme - volume:119
Enthalten in:	The American journal of cardiology - 119(2017), 8, Seite 1156-1161

Sprache:	Englisch

Beteiligte Personen:	Apfaltrer, Georg [VerfasserIn] Dutschke, Anja, 1988- [VerfasserIn] Apfaltrer, Paul, 1983- [VerfasserIn]

Links:	Volltext

Themen:	Adult Aged Aged, 80 and over Cardiac-Gated Imaging Techniques Coronary Angiography Coronary Artery Disease Electrocardiography Female Humans Image Processing, Computer-Assisted Male Middle Aged Radiation Dosage Retrospective Studies Tomography, X-Ray Computed

Anmerkungen:	Available online 25 January 2017 Gesehen am 28.06.2018

Umfang:	6

doi:	10.1016/j.amjcard.2016.12.028

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1577003039

Internformat


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520			\|a The aim of this study was to assess the image quality (IQ) and radiation dose of third-generation dual-source computed tomography (CT) coronary angiography (cCTA) in comparison with 64-slice single-source CT. This retrospective study included 140 patients (73 men, mean age 62 ± 11 years) with low-to-intermediate probability of coronary artery disease who underwent either third-generation dual-source cCTA using prospectively electrocardiography-triggered high-pitch spiral acquisition (n = 70) (group 1) or retrospective electrocardiography-gated cCTA on a 64-slice CT system (n = 70) (group 2). Contrast-to-noise and signal-to-noise ratios were measured within the aorta and coronary arteries. Subjective IQ was assessed using a 5-point Likert scale. Effective dose was estimated using specific conversion factors. The contrast-to-noise ratio of group 1 was significantly higher than group 2 at all levels (all p <0.001). Signal-to-noise ratio of group 1 was also significantly higher than group 2 (p <0.05), except for the distal left circumflex artery. Subjective IQ for group 1 was rated significantly better than for group 2 (median score [25th to 75th percentile]: 1 [1 to 2] vs 2 [2 to 3]; p <0.001). The median effective dose was 1.55 mSv (1.09 to 1.88) in group 1 versus 12.29 mSv (11.63 to 14.36) in group 2 (p <0.001) which corresponds to a mean radiation dose reduction of 87.4%. In conclusion, implementation of third-generation dual-source CT system for cCTA leads to improved IQ with significant radiation dose savings.
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