Details der Publikation - Multimodal functional imaging of prolonged neurological deficits in a patient suffering from familial hemiplegic migraine

Multimodal functional imaging of prolonged neurological deficits in a patient suffering from familial hemiplegic migraine / Alexander Gutschalk, Rainer Kollmar, Alexander Mohr, Marcus Henze, Nicole Ille, Markus Schwaninger, Marius Hartmann, Stefan Hähnel, Uwe Haberkorn, André Rupp, Uta Meyding-Lamade

The case of a patient with familial hemiplegic migraine (FHM) suffering from prolonged right sided hemiparesis and aphasia that persisted for more than 10 days is reported. The symptoms were accompanied by slowing of the magnetoencephalogram over the left hemisphere, which normalized parallel to the clinical improvement. Positron emission tomography obtained on the 6th day revealed glucose-hypometabolism (hemispheric difference > or =10%) in left hemisphere's fronto-basal cortex, caudate nucleus, and thalamus. In contrast, magnetic resonance imaging including perfusion and diffusion weighted imaging was normal and did not show significant alterations of cortical perfusion or water mobility during the episode. We hypothesize that this finding provides evidence for a primary neuronal dysfunction causing the prolonged neurological deficits in FHM..

Medienart:	E-Artikel

Erscheinungsjahr:	10 October 2002 2002
Erschienen:	10 October 2002

Enthalten in:	Zur Gesamtaufnahme - volume:332
Enthalten in:	Neuroscience letters - 332(2002), 2, Seite 115-118

Sprache:	Englisch

Beteiligte Personen:	Gutschalk, Alexander, 1973- [VerfasserIn] Kollmar, Rainer, 1972- [VerfasserIn] Mohr, Alexander, 1970- [VerfasserIn] Henze, Marcus [VerfasserIn] Ille, Nicole [VerfasserIn] Schwaninger, Markus [VerfasserIn] Hartmann, Marius [VerfasserIn] Hähnel, Stefan, 1966- [VerfasserIn] Haberkorn, Uwe, 1959- [VerfasserIn] Rupp, André, 1962- [VerfasserIn] Meyding-Lamadé, Uta [VerfasserIn]

Themen:	Adult Aphasia Brain Chemistry Chromosomes, Human, Pair 19 Follow-Up Studies Glucose Hemiplegia Humans Magnetic Resonance Imaging Magnetoencephalography Male Migraine Disorders Nervous System Diseases Tomography, Emission-Computed Ultrasonography, Doppler, Transcranial

Anmerkungen:	Gesehen am 25.10.2017

Umfang:	4

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1564764028

Internformat


LEADER	01000caa a2200265 4500
001	1564764028
003	DE-627
005	20230427142100.0
007	cr uuu---uuuuu
008	171025s2002 xx \|\|\|\|\|o 00\| \|\|eng c
035			\|a (DE-627)1564764028
035			\|a (DE-576)494764023
035			\|a (DE-599)BSZ494764023
035			\|a (OCoLC)1340981062
040			\|a DE-627 \|b ger \|c DE-627 \|e rda
041			\|a eng
100	1		\|a Gutschalk, Alexander \|d 1973- \|e verfasserin \|0 (DE-588)122527496 \|0 (DE-627)705940225 \|0 (DE-576)293308926 \|4 aut
245	1	0	\|a Multimodal functional imaging of prolonged neurological deficits in a patient suffering from familial hemiplegic migraine \|c Alexander Gutschalk, Rainer Kollmar, Alexander Mohr, Marcus Henze, Nicole Ille, Markus Schwaninger, Marius Hartmann, Stefan Hähnel, Uwe Haberkorn, André Rupp, Uta Meyding-Lamade
264		1	\|c 10 October 2002
300			\|a 4
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
500			\|a Gesehen am 25.10.2017
520			\|a The case of a patient with familial hemiplegic migraine (FHM) suffering from prolonged right sided hemiparesis and aphasia that persisted for more than 10 days is reported. The symptoms were accompanied by slowing of the magnetoencephalogram over the left hemisphere, which normalized parallel to the clinical improvement. Positron emission tomography obtained on the 6th day revealed glucose-hypometabolism (hemispheric difference > or =10%) in left hemisphere's fronto-basal cortex, caudate nucleus, and thalamus. In contrast, magnetic resonance imaging including perfusion and diffusion weighted imaging was normal and did not show significant alterations of cortical perfusion or water mobility during the episode. We hypothesize that this finding provides evidence for a primary neuronal dysfunction causing the prolonged neurological deficits in FHM.
650		4	\|a Humans
650		4	\|a Male
650		4	\|a Adult
650		4	\|a Glucose
650		4	\|a Tomography, Emission-Computed
650		4	\|a Aphasia
650		4	\|a Brain Chemistry
650		4	\|a Chromosomes, Human, Pair 19
650		4	\|a Follow-Up Studies
650		4	\|a Hemiplegia
650		4	\|a Magnetic Resonance Imaging
650		4	\|a Magnetoencephalography
650		4	\|a Migraine Disorders
650		4	\|a Nervous System Diseases
650		4	\|a Ultrasonography, Doppler, Transcranial
700	1		\|a Kollmar, Rainer \|d 1972- \|e verfasserin \|0 (DE-588)123452244 \|0 (DE-627)082564949 \|0 (DE-576)293715556 \|4 aut
700	1		\|a Mohr, Alexander \|d 1970- \|e verfasserin \|0 (DE-588)140043888 \|0 (DE-627)615245463 \|0 (DE-576)314321136 \|4 aut
700	1		\|a Henze, Marcus \|e verfasserin \|0 (DE-588)1076102921 \|0 (DE-627)834307081 \|0 (DE-576)175599408 \|4 aut
700	1		\|a Ille, Nicole \|e verfasserin \|0 (DE-588)1142262316 \|0 (DE-627)1001435575 \|0 (DE-576)184687462 \|4 aut
700	1		\|a Schwaninger, Markus \|e verfasserin \|0 (DE-588)1028374909 \|0 (DE-627)730623939 \|0 (DE-576)375910174 \|4 aut
700	1		\|a Hartmann, Marius \|e verfasserin \|0 (DE-588)1071907441 \|0 (DE-627)826599524 \|0 (DE-576)433420960 \|4 aut
700	1		\|a Hähnel, Stefan \|d 1966- \|e verfasserin \|0 (DE-588)113981937 \|0 (DE-627)558821138 \|0 (DE-576)289781639 \|4 aut
700	1		\|a Haberkorn, Uwe \|d 1959- \|e verfasserin \|0 (DE-588)1022913905 \|0 (DE-627)717331245 \|0 (DE-576)366166352 \|4 aut
700	1		\|a Rupp, André \|d 1962- \|e verfasserin \|0 (DE-588)121268527 \|0 (DE-627)705347079 \|0 (DE-576)181320827 \|4 aut
700	1		\|a Meyding-Lamadé, Uta \|e verfasserin \|0 (DE-588)1065275005 \|0 (DE-627)815798652 \|0 (DE-576)424952203 \|4 aut
773	0	8	\|i Enthalten in \|t Neuroscience letters \|d Amsterdam [u.a.] : Elsevier Science, 1975 \|g 332(2002), 2, Seite 115-118 \|h Online-Ressource \|w (DE-627)306589699 \|w (DE-600)1498535-4 \|w (DE-576)081953119 \|x 1872-7972 \|7 nnns
773	1	8	\|g volume:332 \|g year:2002 \|g number:2 \|g pages:115-118 \|g extent:4
912			\|a GBV_USEFLAG_U
912			\|a GBV_ILN_2013
912			\|a ISIL_DE-16-250
912			\|a SYSFLAG_1
912			\|a GBV_KXP
912			\|a SSG-OLC-PHA
912			\|a GBV_ILN_11
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_120
912			\|a GBV_ILN_121
912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_152
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_374
912			\|a GBV_ILN_602
912			\|a GBV_ILN_647
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2018
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2043
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2116
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2158
912			\|a GBV_ILN_2188
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2193
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2446
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2472
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_2548
912			\|a GBV_ILN_2807
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4046
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4246
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4277
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4328
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4336
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4346
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
912			\|a GBV_ILN_4753
936	u	w	\|d 332 \|j 2002 \|e 2 \|h 115-118 \|g 4
951			\|a AR
952			\|d 332 \|j 2002 \|e 2 \|h 115-118 \|g 4
980			\|2 2013 \|1 01 \|x DE-16-250 \|b 2986038271 \|c 00 \|f --%%-- \|d --%%-- \|e --%%-- \|j --%%-- \|y l01 \|z 25-10-17
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 00 \|s s \|a hd2002
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 01 \|s s \|0 (DE-627)1410508463 \|a wissenschaftlicher Artikel (Zeitschrift)
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 02 \|s s \|a per_11
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 03 \|s s \|a s_4
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s p \|0 (DE-627)1485694817 \|a Gutschalk, Alexander
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s s \|a pos_1
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 05 \|s p \|0 (DE-627)1494922452 \|a Kollmar, Rainer
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 05 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 05 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 05 \|s s \|a pos_2
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 06 \|s p \|0 (DE-627)1512590541 \|a Mohr, Alexander
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 06 \|s k \|0 (DE-627)1416741399 \|a Radiologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 06 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 06 \|s s \|a pos_3
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 07 \|s p \|0 (DE-627)151488089X \|a Henze, Marcus
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 07 \|s k \|0 (DE-627)1416741399 \|a Radiologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 07 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 07 \|s s \|a pos_4
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 08 \|s p \|0 (DE-627)1564764389 \|a Ille, Nicole
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 08 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 08 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 08 \|s s \|a pos_5
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 09 \|s p \|0 (DE-627)1447871960 \|a Schwaninger, Markus
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 09 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 09 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 09 \|s s \|a pos_6
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 10 \|s p \|0 (DE-627)1503422011 \|a Hartmann, Marius
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 10 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 10 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 10 \|s s \|a pos_7
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 11 \|s p \|0 (DE-627)1450184227 \|a Hähnel, Stefan
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 11 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 11 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 11 \|s s \|a pos_8
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 12 \|s p \|0 (DE-627)1436166667 \|a Haberkorn, Uwe
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 12 \|s k \|0 (DE-627)1416741399 \|a Radiologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 12 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 12 \|s s \|a pos_9
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 13 \|s p \|0 (DE-627)1474492096 \|a Rupp, André
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 13 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 13 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 13 \|s s \|a pos_10
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 14 \|s p \|0 (DE-627)1494923092 \|a Meyding-Lamadé, Uta
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 14 \|s k \|0 (DE-627)1416741267 \|a Neurologische Universitätsklinik
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 14 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 14 \|s s \|a pos_11

Zugang & Verfügbarkeit

Zugehörige Publikationen/Bände