Details der Publikation - Epigenetics of aging and longevity

Epigenetics of aging and longevity / edited by Alexey Moskalev (Institute of Biology, Komi Science Center of RAS, Syktyvar, Russia, Moscow Institute of Physics and Technology (MIPT), Dolgoprudny, Russia, Engelhardt Institute of Molecular Biology RAS, Moscow, Rusia), Alexander M. Vaiserman (Institute of Gerontology, Kiev, Ukraine)

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related diseaseProvides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectoryApplies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan.

Medienart:	E-Book

Erscheinungsjahr:	Elsevier
Erschienen:	London: Elsevier

Reproduktion:	Online-Ausg.
Weitere Ausgaben:	Erscheint auch als Druck-Ausgabe: Epigenetics of aging and longevity

Reihe:	Translational epigenetics series - volume 4

Sprache:	Englisch

Beteiligte Personen:	Moskalev, Alexey, 1976- [HerausgeberIn] Vaiserman, Alexander M. [HerausgeberIn]

Links:	Volltext www.sciencedirect.com [lizenzpflichtig]

ISBN:	978-0-12-811060-7

Nlm:	QU 475
Themen:	�Epig�en�ese �Epig�en�etique Aged Aging Aging ; Genetic aspects Altern Elderly Electronic books Epigenesis Epigenesis, Genetic Epigenetics Epigenetik Epigenomics G�erontologie Geriatrics Gerontology Humans Langlebigkeit Long�evit�e Longevity Older people Personnes �ag�ees SCIENCE / Life Sciences / Biochemistry Vieillissement - Aspect g�en�etique

RVK:	RVK Klassifikation WB 1080

Anmerkungen:	Includes index

Umfang:	1 Online-Ressource (520 Seiten)

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	1024673529

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520			\|a Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related diseaseProvides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectoryApplies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan
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