Suchergebnisse - "Uehara, Shotaro"

PubPharm (189)

1

In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells

enthalten in: Chemical research in toxicology | 2024

von Uehara, S. | Murayama, N. | Higuchi, Y. | +4

2

Comprehensive gene profiling of the metabolic landscape of humanized livers in mice

enthalten in: Journal of hepatology | 2024

von Jiang, C. | Li, P. | Ma, Y. | +6

3

Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css-MRTpo method and chimeric mice with humanised livers

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Kamimura, H. | Uehara, S. | Yoneda, N. | +1

4

Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Uno, Y. | Uehara, S. | Ushirozako, G. | +3

5

Pharmacokinetic Models Scaled-up from Humanized-liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and N-Demethylated Metabolites i n Pediatric Patients Genotyped for Cytochrome P450 2D6

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2023

von Shimizu, M. | Uehara, S. | Ohyama, K. | +6

6

Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Uno, Y. | Uehara, S. | Ushirozako, G. | +2

7

SGX523 causes renal toxicity through aldehyde oxidase-mediated less-soluble metabolite formation in chimeric mice with humanized livers

enthalten in: Toxicology letters | 2023

von Uehara, S. | Yasuda, M. | Higuchi, Y. | +5

8

Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers

enthalten in: Toxicology in vitro : an international journal published in association with BIBRA | 2023

von Zerdoug, A. | Le Vée, M. | Uehara, S. | +7

9

HepaSH cells : Experimental human hepatocytes with lesser inter-individual variation and more sustainable availability than primary human hepatocytes

enthalten in: Biochemical and biophysical research communications | 2023

von Uehara, S. | Higuchi, Y. | Yoneda, N. | +8

10

Roles of human cytochrome P450 3A4/5 in dexamethasone 6β-hydroxylation mediated by liver microsomes and humanized liver in chimeric mice metabolically suppressed with azamulin

enthalten in: Drug metabolism and pharmacokinetics | 2023

von Uehara, S. | Shimizu, M. | Suemizu, H. | +1

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