Suchergebnisse - "Tsunenari, Yoshihiko"

PubPharm (13)

1

Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2020

von Ogawa, S. | Uehara, S. | Tsunenari, Y. | +3

2

Syntheses and pharmacokinetic evaluations of four metabolites of 2-(4-(2-((1H-benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis-(methylthio)pyridin-3-yl)acetamide hydrochloride [K-604], an acyl-CoA:cholesterol O-acyltransferase-1 inhibitor

enthalten in: Bioorganic & medicinal chemistry | 2020

von Shibuya, K. | Miura, T. | Ohgiya, T. | +2

3

Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver

enthalten in: Xenobiotica | 2020

von Ogawa, S. | Uehara, S. | Tsunenari, Y. | +3

4

Brain Targeting of Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor K-604 via the Intranasal Route Using a Hydroxycarboxylic Acid Solution

enthalten in: ACS omega | 2019

von Shibuya, K. | Morikawa, S. | Miyamoto, M. | +4

5

Pharmacokinetics and metabolism of pemafibrate, a novel selective peroxisome proliferator-activated receptor-alpha modulator, in rats and monkeys

enthalten in: Biopharmaceutics & drug disposition | 2019

von Ogawa, S. | Tsunenari, Y. | Kawai, H. | +1

6

Discovery of Clinical Candidate 2-(4-(2-((1 H-Benzo[ d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)- N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide Hydrochloride [K-604], an Aqueous-Soluble Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor

enthalten in: Journal of medicinal chemistry | 2018

von Shibuya, K. | Kawamine, K. | Ozaki, C. | +4

7

Design, synthesis and pharmacology of aortic-selective acyl-CoA : Cholesterol O-acyltransferase (ACAT/SOAT) inhibitors

enthalten in: Bioorganic & medicinal chemistry | 2018

von Shibuya, K. | Kawamine, K. | Miura, T. | +5

8

Effect of gemfibrozil on the metabolism of pitavastatin--determining the best animal model for human CYP and UGT activities

enthalten in: Drug metabolism and drug interactions | 2004

von Fujino, H. | Saito, T. | Tsunenari, Y. | +1

9

INTERACTION BETWEEN FIBRATES AND STATINS - METABOLIC INTERACTIONS WITH GEMFIBROZIL

enthalten in: Drug metabolism and drug interactions | 2003

von Fujino, H. | Yamada, I. | Shimada, S. | +3

10

INTERACTION BETWEEN FIBRATES AND STATINS - METABOLIC INTERACTIONS WITH GEMFIBROZIL

enthalten in: Drug metabolism and drug interactions | 2003

von Fujino, H. | Yamada, I. | Shimada, S. | +3