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PubPharm (21)
1
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants
enthalten in:
Emerging microbes & infections
| 2023
von
Pérez-Vargas, J.
|
Worrall, L.
|
Olmstead, A.
| +27
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2
MYC-MAX INHIBITORS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH
enthalten in:
Europäisches Patentamt
| 2023
von
TCHERKASSOV ARTEM
|
RENNIE PAUL
|
BAN FUQIANG
| +6
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3
MYC-MAX INHIBITORS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH
enthalten in:
Europäisches Patentamt
| 2023
von
TCHERKASSOV ARTEM
|
RENNIE PAUL
|
BAN FUQIANG
| +6
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4
Large-Scale Virtual Screening for the Discovery of SARS-CoV-2 Papain-like Protease (PLpro) Non-covalent Inhibitors
enthalten in:
Journal of chemical information and modeling
| 2023
von
Garland, O.
|
Ton, A.
|
Moradi, S.
| +12
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5
Targeting SARS-CoV-2 papain-like protease in the postvaccine era
enthalten in:
Trends in pharmacological sciences
| 2022
von
Ton, A.
|
Pandey, M.
|
Smith, J.
| +3
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6
X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation
enthalten in:
Nature communications
| 2022
von
Lee, J.
|
Kenward, C.
|
Worrall, L.
| +7
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7
Inferring the selection window in antimicrobial resistance using deep mutational scanning data and biophysics-based fitness models
enthalten in:
bioRxiv.org
| 2022
von
Dasmeh, P.
|
Ton, A.
|
Quach, C.
| +1
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8
Artificial intelligence-enabled virtual screening of ultra-large chemical libraries with deep docking
enthalten in:
Nature protocols
| 2022
von
Gentile, F.
|
Yaacoub, J.
|
Gleave, J.
| +5
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9
Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer
enthalten in:
International journal of molecular sciences
| 2022
von
Ton, A.
|
Foo, J.
|
Singh, K.
| +8
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10
Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease by consensus Deep Docking of 40 billion small molecules
enthalten in:
Chemical science
| 2021
von
Gentile, F.
|
Fernandez, M.
|
Ban, F.
| +11
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Thema
14
Journal Article
9
Research Support, Non-U.S. Gov't
4
Antiviral Agents
4
Protease Inhibitors
4
Research Support, N.I.H., Extramural
3
615
3
A61K: Preparations for medical, dental, or toil...
3
A61P: Specific therapeutic activity of chemical...
3
C07C: Acyclic or carbocyclic compounds (macromo...
3
C07D: Heterocyclic compounds (macromolecular co...
3
Review
3
che
3
computer-aided drug design
2
Antineoplastic Agents
2
COVID-19
2
Coronavirus 3C Proteases
2
Cysteine Endopeptidases
2
EC 3.4.-
2
EC 3.4.22.-
2
EC 3.4.22.2
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Erscheinungszeitraum
18
2020-
3
2010-2019
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Sprache
19
Englisch
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