Suchergebnisse - "Suemizu, Hiroshi"

PubPharm (260)

1

In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells

enthalten in: Chemical research in toxicology | 2024

von Uehara, S. | Murayama, N. | Higuchi, Y. | +4

2

Comprehensive gene profiling of the metabolic landscape of humanized livers in mice

enthalten in: Journal of hepatology | 2024

von Jiang, C. | Li, P. | Ma, Y. | +6

3

A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures

enthalten in: Toxicology research | 2024

von Aslamkhan, A. | Michna, L. | Podtelezhnikov, A. | +18

4

Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css-MRTpo method and chimeric mice with humanised livers

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Kamimura, H. | Uehara, S. | Yoneda, N. | +1

5

Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Uno, Y. | Uehara, S. | Ushirozako, G. | +3

6

Pharmacokinetic Models Scaled-up from Humanized-liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and N-Demethylated Metabolites i n Pediatric Patients Genotyped for Cytochrome P450 2D6

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2023

von Shimizu, M. | Uehara, S. | Ohyama, K. | +6

7

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

enthalten in: bioRxiv.org | 2023

von Kabbani, M. | Michailidis, E. | Steensels, S. | +28

8

SGX523 causes renal toxicity through aldehyde oxidase-mediated less-soluble metabolite formation in chimeric mice with humanized livers

enthalten in: Toxicology letters | 2023

von Uehara, S. | Yasuda, M. | Higuchi, Y. | +5

9

Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers

enthalten in: Toxicology in vitro : an international journal published in association with BIBRA | 2023

von Zerdoug, A. | Le Vée, M. | Uehara, S. | +7

10

Single transcript-level metabolic responsive landscape of human liver transcriptome

enthalten in: bioRxiv.org | 2023

von Jiang, C. | Li, P. | Ma, Y. | +5

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