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PubPharm (351)
1
Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources
enthalten in:
Drug metabolism and pharmacokinetics
| 2024
von
Shimizu, M.
|
Makiguchi, M.
|
Hishinuma, E.
| +3
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2
In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells
enthalten in:
Chemical research in toxicology
| 2024
von
Uehara, S.
|
Murayama, N.
|
Higuchi, Y.
| +4
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3
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models
enthalten in:
Biochemical pharmacology
| 2024
von
Uno, Y.
|
Shimizu, M.
|
Yamazaki, H.
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4
Molecular and functional characterization of flavin-containing monooxygenases (FMO1-6) in tree shrews
enthalten in:
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
| 2024
von
Uno, Y.
|
Makiguchi, M.
|
Ushirozako, G.
| +3
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5
Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C9*3 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database
enthalten in:
Biological & pharmaceutical bulletin
| 2024
von
Adachi, K.
|
Ohyama, K.
|
Tanaka, Y.
| +3
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6
Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated in silico as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances
enthalten in:
The Journal of toxicological sciences
| 2024
von
Adachi, K.
|
Shimizu, M.
|
Shono, F.
| +2
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7
Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank
enthalten in:
Drug metabolism and pharmacokinetics
| 2023
von
Shimizu, M.
|
Makiguchi, M.
|
Yokota, Y.
| +5
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8
A decreasing plasma concentration of a toxicologically active metabolite 9-carboxymethoxymethylguanine after dialysis - A potential new clinical biomarker for improving encephalopathy in patients treated with acyclovir
enthalten in:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
| 2023
von
Unita, R.
|
Adachi, K.
|
Inada, A.
| +3
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9
Pharmacokinetic Models Scaled-up from Humanized-liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and N-Demethylated Metabolites i n Pediatric Patients Genotyped for Cytochrome P450 2D6
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2023
von
Shimizu, M.
|
Uehara, S.
|
Ohyama, K.
| +6
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10
Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection
enthalten in:
Journal of pharmaceutical health care and sciences
| 2023
von
Negishi, D.
|
Mitsumatsu, O.
|
Mitsumatsu, H.
| +3
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351
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Drug metabolism and pharmacokinetics
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Xenobiotica
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Chemical research in toxicology
18
Journal of pharmaceutical health care and sciences
18
Xenobiotica; the fate of foreign compounds in b...
16
Biochemical pharmacology
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The Journal of toxicological sciences
13
Biological & pharmaceutical bulletin
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Drug metabolism and disposition: the biological...
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Biopharmaceutics & drug disposition
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Human molecular genetics
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British journal of clinical pharmacology
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European journal of clinical pharmacology
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Human genetics <Berlin>
4
Journal of human genetics
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Thema
232
Journal Article
96
Research Support, Non-U.S. Gov't
42
EC 1.14.13.8
42
EC 1.14.14.1
42
dimethylaniline monooxygenase (N-oxide forming)
41
EC 1.13.-
41
Oxygenases
25
9035-51-2
25
Cytochrome P-450 Enzyme System
22
Methylamines
21
PBPK modeling
21
trimethylamine
19
LHH7G8O305
17
FMO3
16
Cytochrome P-450 CYP3A
14
Pharmaceutical Preparations
13
Comparative Study
13
Research Support, N.I.H., Extramural
12
4Z8R6ORS6L
12
Allometric scaling
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Erscheinungszeitraum
100
2020-
164
2010-2019
74
2000-2009
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298
Englisch
5
Japanisch
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