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PubPharm (20)
1
Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Ogawa, S.
|
Shimizu, M.
|
Yamazaki, H.
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2
Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Ogawa, S.
|
Shimizu, M.
|
Yamazaki, H.
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3
Increased plasma concentrations of an antidyslipidemic drug pemafibrate co-administered with rifampicin or cyclosporine A in cynomolgus monkeys genotyped for the organic anion transporting polypeptide 1B1
enthalten in:
Drug metabolism and pharmacokinetics
| 2020
von
Ogawa, S.
|
Shimizu, M.
|
Kamiya, Y.
| +3
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4
Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Ogawa, S.
|
Uehara, S.
|
Tsunenari, Y.
| +3
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5
Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver
enthalten in:
Xenobiotica
| 2020
von
Ogawa, S.
|
Uehara, S.
|
Tsunenari, Y.
| +3
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6
Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment
enthalten in:
Xenobiotica
| 2020
von
Ogawa, S.
|
Shimizu, M.
|
Yamazaki, H.
Wird geladen...
7
Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations
enthalten in:
Xenobiotica
| 2020
von
Ogawa, S.
|
Shimizu, M.
|
Yamazaki, H.
Wird geladen...
8
Brain Targeting of Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor K-604 via the Intranasal Route Using a Hydroxycarboxylic Acid Solution
enthalten in:
ACS omega
| 2019
von
Shibuya, K.
|
Morikawa, S.
|
Miyamoto, M.
| +4
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9
Pharmacokinetics and metabolism of pemafibrate, a novel selective peroxisome proliferator-activated receptor-alpha modulator, in rats and monkeys
enthalten in:
Biopharmaceutics & drug disposition
| 2019
von
Ogawa, S.
|
Tsunenari, Y.
|
Kawai, H.
| +1
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10
Induction of oligodendrocyte differentiation from adult human fibroblast-derived induced pluripotent stem cells
enthalten in:
In vitro cellular & developmental biology. Animal
| 2011
von
Ogawa, S.
|
Tokumoto, Y.
|
Miyake, J.
| +1
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Journal Article
6
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphen...
6
Benzoxazoles
6
Butyrates
4
PBPK
4
organic anion transporting polypeptide
3
Human
3
Induced pluripotent stem cell
3
Myelin
3
Oligodendrocyte
3
species difference
2
Humanized-liver mice
2
Liver-Specific Organic Anion Transporter 1
2
PPAR alpha
2
Research Support, Non-U.S. Gov't
2
clarithromycin
2
clopidogrel
2
cytochrome P450
2
fluconazole
2
metabolic pathways
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Erscheinungszeitraum
7
2020-
9
2010-2019
4
2000-2009
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16
Englisch
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