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PubPharm (36)
1
Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease
enthalten in:
Journal of medicinal chemistry
| 2024
von
Terrett, J.
|
Ly, J.
|
Katavolos, P.
| +53
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2
Towards in vitro models for reducing or replacing the use of animals in drug testing
enthalten in:
Nature biomedical engineering
| 2023
von
Stresser, D.
|
Kopec, A.
|
Hewitt, P.
| +24
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3
A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
enthalten in:
Leukemia
| 2022
von
Kakiuchi-Kiyota, S.
|
Ross, T.
|
Wallweber, H.
| +27
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4
Perspectives on the evaluation and adoption of complex in vitro models in drug development : Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)
enthalten in:
ALTEX
| 2022
von
Baran, S.
|
Brown, P.
|
Baudy, A.
| +24
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5
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2 : Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
enthalten in:
Journal of medicinal chemistry
| 2021
von
Dragovich, P.
|
Pillow, T.
|
Blake, R.
| +34
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6
An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias
enthalten in:
bioRxiv.org
| 2020
von
Wilson, J.
|
Lu, D.
|
Corr, N.
| +2
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7
In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk
enthalten in:
Archives of toxicology
| 2020
von
Norona, L.
|
Fullerton, A.
|
Lawson, C.
| +6
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8
An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias
enthalten in:
PLoS computational biology
| 2020
von
Wilson, J.
|
Lu, D.
|
Corr, N.
| +2
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9
In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk
enthalten in:
Archives of toxicology
| 2020
von
Norona, L.
|
Fullerton, A.
|
Lawson, C.
| +6
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10
In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk
enthalten in:
Archives of toxicology
| 2020
von
Norona, L.
|
Fullerton, A.
|
Lawson, C.
| +6
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7
Research Support, N.I.H., Extramural
7
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5
Hepatotoxicity
4
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4
Cholestasis
4
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4
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4
FXR antagonism
3
11028-71-0
3
9F388J00UK
3
Concanavalin A
3
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3
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3
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3
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3
UQT9G45D1P
3
trovafloxacin
2
82115-62-6
2
Anesthetics, Inhalation
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Erscheinungszeitraum
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2020-
16
2010-2019
6
2000-2009
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