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journalStr:"Journal of medicinal chemistry"
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PubPharm (11)
1
Enantioselective Synthesis and Biological Evaluation of Pyrrolidines Bearing Quaternary Stereogenic Centers
enthalten in:
Journal of medicinal chemistry
| 2023
von
Qiu, H.
|
Du, Z.
|
Zhao, Y.
| +11
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2
Discovery of 4H-Chromen-4-one Derivatives as a New Class of Selective Rho Kinase (ROCK) Inhibitors, which Showed Potent Activity in ex Vivo Diabetic Retinopathy Models
enthalten in:
Journal of medicinal chemistry
| 2019
von
Zhao, L.
|
Li, Y.
|
Wang, Y.
| +8
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3
Correction to Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model
enthalten in:
Journal of medicinal chemistry
| 2019
von
Li, Y.
|
Xiong, Y.
|
Zhang, G.
| +13
ErratumFor: J Med Chem. 2018 Nov 27;:. - PMID 30480444
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4
Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model
enthalten in:
Journal of medicinal chemistry
| 2018
von
Li, Y.
|
Xiong, Y.
|
Zhang, G.
| +13
ErratumIn: J Med Chem. 2019 Mar 28;62(6):3169. - PMID 30843694
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5
From Lead to Drug Candidate : Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer
enthalten in:
Journal of medicinal chemistry
| 2016
von
Zhang, C.
|
Chen, K.
|
Jiao, Y.
| +15
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6
Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer
enthalten in:
Journal of medicinal chemistry
| 2015
von
Zhang, C.
|
Zheng, M.
|
Li, Y.
| +15
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7
Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer
enthalten in:
Journal of medicinal chemistry
| 2015
von
Zhang, C.
|
Zheng, M.
|
Li, Y.
| +15
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8
Structural optimization and structure-activity relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine derivatives, a new class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations
enthalten in:
Journal of medicinal chemistry
| 2012
von
Yang, J.
|
Wang, L.
|
Liu, J.
| +10
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9
Structural Optimization and Structure–Activity Relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine Derivatives, a New Class of Reversible Kinase Inhibitors Targeting both EGFR-Activating and Resistance Mutations
enthalten in:
Journal of medicinal chemistry
| 2012
von
Yang, J.
|
Wang, L.
|
Liu, J.
| +10
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10
Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo
enthalten in:
Journal of medicinal chemistry
| 2012
von
Li, W.
|
Wang, X.
|
Zheng, R.
| +16
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1
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Zeitschrift: Journal of medicinal chemistry
Medienart
11
Aufsätze
8
E-Artikel
8
E-Ressourcen
3
Gedruckte Aufsätze
Zeitschriftentitel
Journal of medicinal chemistry
Thema
8
Journal Article
7
Research Support, Non-U.S. Gov't
4
Antineoplastic Agents
3
Protein Kinase Inhibitors
2
EC 2.7.10.1
2
EC 2.7.11.1
2
Pyrazoles
2
Pyrimidines
1
1-(5-(7-(3-morpholinopropoxy)quinazolin-4-ylthi...
1
3-((4-amino-1-ethyl-1H-pyrazolo(3,4-d)pyrimidin...
1
3-(phenylethynyl)-1H-pyrazolo(3,4-d)pyrimidin-4...
1
Acetylene
1
Acetylene - analogs & derivatives
1
Acetylene - chemistry
1
Acetylene - pharmacokinetics
1
Acetylene - pharmacology
1
Antineoplastic Agents - chemistry
1
Antineoplastic Agents - pharmacokinetics
1
Antineoplastic Agents - pharmacology
1
Apoptosis - drug effects
Alle anzeigen ...
weniger ...
Erscheinungszeitraum
1
2020-
10
2010-2019
Erscheinungsjahr(e)
Von:
Bis:
Sprache
9
Englisch
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