Suchergebnisse - "Swingle, Mark R"

PubPharm (32)

1

B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations

enthalten in: Proceedings of the National Academy of Sciences of the United States of America | 2024

von Wu, C. | Balakrishnan, V. | Merrill, R. | +16

2

Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades

enthalten in: The Journal of biological chemistry | 2023

von Smolen, K. | Papke, C. | Swingle, M. | +6

UpdateOf: bioRxiv. 2023 Mar 27;:. - PMID 37034727

3

Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme

enthalten in: bioRxiv.org | 2023

von Wu, C. | Balakrishnan, V. | Parihar, P. | +16

4

Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme

enthalten in: bioRxiv : the preprint server for biology | 2023

von Wu, C. | Balakrishnan, V. | Parihar, P. | +16

5

Quantum-based modeling implies that bidentate Arg89-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation

enthalten in: Frontiers in cell and developmental biology | 2023

von Salter, E. | Wierzbicki, A. | Honkanen, R. | +1

6

The phosphatase inhibitor LB-100 acts synergistically with the NPR2 agonist BMN-111 to improve bone growth

enthalten in: bioRxiv.org | 2022

von Shuhaibar, L. | Kaci, N. | Egbert, J. | +8

7

Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth

enthalten in: JCI insight | 2021

von Shuhaibar, L. | Kaci, N. | Egbert, J. | +10

8

A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth

enthalten in: The Journal of biological chemistry | 2021

von Papke, C. | Smolen, K. | Swingle, M. | +9

9

Development of a Synthetic 3-ketosteroid Δ1-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells

enthalten in: Scientific reports | 2019

von D'Arcy, B. | Swingle, M. | Schambeau, L. | +3

10

The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C

enthalten in: Molecular cancer therapeutics | 2019

von D'Arcy, B. | Swingle, M. | Papke, C. | +4