Suchergebnisse - "Ruza, Reinis R"

PubPharm (16)

1

Structural Analysis and Development of Notum Fragment Screening Hits

enthalten in: ACS chemical neuroscience | 2022

von Zhao, Y. | Mahy, W. | Willis, N. | +18

2

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

enthalten in: Journal of medicinal chemistry | 2022

von Willis, N. | Mahy, W. | Sipthorp, J. | +21

3

The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer

enthalten in: bioRxiv.org | 2021

von Carrique, L. | Duyvesteyn, H. | Malinauskas, T. | +10

4

Neutralization of SARS-CoV-2 by destruction of the prefusion Spike

enthalten in: bioRxiv.org | 2021

von Huo, J. | Zhao, Y. | Ren, J. | +21

5

Author Correction : Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

enthalten in: Nature structural & molecular biology | 2021

von Huo, J. | Bas, A. | Ruza, R. | +30

ErratumFor: Nat Struct Mol Biol. 2020 Sep;27(9):846-854. - PMID 32661423

6

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

enthalten in: bioRxiv.org | 2020

von Zhou, D. | Duyvesteyn, H. | Chen, C. | +37

7

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

enthalten in: Journal of medicinal chemistry | 2020

von Mahy, W. | Willis, N. | Zhao, Y. | +15

8

Author Correction : Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

enthalten in: Nature structural & molecular biology | 2020

von Huo, J. | Le Bas, A. | Ruza, R. | +30

ErratumFor: Nat Struct Mol Biol. 2020 Sep;27(9):846-854. - PMID 32661423

9

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

enthalten in: Nature structural & molecular biology | 2020

von Zhou, D. | Duyvesteyn, H. | Chen, C. | +37

10

Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity

enthalten in: Journal of medicinal chemistry | 2020

von Mahy, W. | Patel, M. | Steadman, D. | +17