Suchergebnisse - "Kowalski, John P"

PubPharm (20)

1

Improved methods for the detection of heme and protoporphyrin IX adducts and quantification of heme B from cytochrome P450 containing systems

enthalten in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences | 2023

von Pelletier, R. | Rettie, A. | Kowalski, J.

2

Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

enthalten in: bioRxiv.org | 2021

von Amorosi, C. | Chiasson, M. | McDonald, M. | +7

3

Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

enthalten in: American journal of human genetics | 2021

von Amorosi, C. | Chiasson, M. | McDonald, M. | +7

4

Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1 : β-oxidation as a potential augmenting pathway for inhibition

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2021

von Kowalski, J. | Pelletier, R. | McDonald, M. | +2

5

Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1:β-oxidation as a potential augmenting pathway for inhibition

enthalten in: Xenobiotica | 2021

von Kowalski, J. | Pelletier, R. | McDonald, M. | +2

6

Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People

enthalten in: The Journal of pharmacology and experimental therapeutics | 2020

von McDonald, M. | Henderson, L. | Ray, S. | +7

7

Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1

enthalten in: Journal of medicinal chemistry | 2020

von Kowalski, J. | McDonald, M. | Pelletier, R. | +3

8

Novel insights into oxidation of fatty acids and fatty alcohols by cytochrome P450 monooxygenase CYP4B1

enthalten in: Archives of biochemistry and biophysics | 2020

von Thesseling, F. | Hutter, M. | Wiek, C. | +3

9

Structure-Activity Relationships for CYP4B1 Bioactivation of 4-Ipomeanol Congeners : Direct Correlation between Cytotoxicity and Trapped Reactive Intermediates

enthalten in: Chemical research in toxicology | 2019

von Kowalski, J. | McDonald, M. | Whittington, D. | +6

10

Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol

enthalten in: The Journal of pharmacology and experimental therapeutics | 2019

von Teitelbaum, A. | McDonald, M. | Kowalski, J. | +7