Suchergebnisse - "Higuchi, Yuichiro"

PubPharm (53)

1

In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells

enthalten in: Chemical research in toxicology | 2024

von Uehara, S. | Murayama, N. | Higuchi, Y. | +4

2

SGX523 causes renal toxicity through aldehyde oxidase-mediated less-soluble metabolite formation in chimeric mice with humanized livers

enthalten in: Toxicology letters | 2023

von Uehara, S. | Yasuda, M. | Higuchi, Y. | +5

3

Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers

enthalten in: Toxicology in vitro : an international journal published in association with BIBRA | 2023

von Zerdoug, A. | Le Vée, M. | Uehara, S. | +7

4

HepaSH cells : Experimental human hepatocytes with lesser inter-individual variation and more sustainable availability than primary human hepatocytes

enthalten in: Biochemical and biophysical research communications | 2023

von Uehara, S. | Higuchi, Y. | Yoneda, N. | +8

5

The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2023

von Uehara, S. | Higuchi, Y. | Yoneda, N. | +3

6

Inhibition of nonhomologous end joining-mediated DNA repair enhances anti-HBV CRISPR therapy

enthalten in: Hepatology communications | 2022

von Murai, K. | Kodama, T. | Hikita, H. | +16

7

Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism

enthalten in: Scientific reports | 2022

von Uehara, S. | Iida, Y. | Ida-Tanaka, M. | +12

8

Cytochrome P450-dependent drug oxidation activities and their expression levels in liver microsomes of chimeric TK-NOG mice with humanized livers

enthalten in: Drug metabolism and pharmacokinetics | 2022

von Uehara, S. | Yoneda, N. | Higuchi, Y. | +2

9

Probe drug T-1032 N-oxygenation mediated by cytochrome P450 3A5 in human hepatocytes in vitro and in humanized-liver mice in vivo

enthalten in: Drug metabolism and pharmacokinetics | 2022

von Uehara, S. | Shimizu, M. | Plé, K. | +5

10

Comparison of mouse and human cytochrome P450 mediated-drug metabolising activities in hepatic and extrahepatic microsomes

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2022

von Uehara, S. | Murayama, N. | Higuchi, Y. | +3

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