Suchergebnisse - "Derks, Michael"

PubPharm (46)

1

A population pharmacokinetics model of balovaptan to support dose selection in adult and pediatric populations

enthalten in: Journal of pharmacokinetics and pharmacodynamics | 2024

von Schaedeli Stark, F. | Chavanne, C. | Derks, M. | +5

2

A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABAA-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome

enthalten in: Journal of neurodevelopmental disorders | 2022

von Goeldner, C. | Kishnani, P. | Skotko, B. | +47

3

A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a $ GABA_{A} $-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome

enthalten in: Journal of neurodevelopmental disorders | 2022

von Goeldner, C. | Kishnani, P. | Skotko, B. | +13

4

A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a $ GABA_{A} $-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome

enthalten in: Journal of neurodevelopmental disorders | 2022

von Goeldner, C. | Kishnani, P. | Skotko, B. | +13

5

A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a $ GABA_{A} $-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome

enthalten in: Journal of neurodevelopmental disorders | 2022

von Goeldner, C. | Kishnani, P. | Skotko, B. | +13

6

Bioavailability and pharmacokinetic profile of balovaptan, a selective, brain-penetrant vasopressin 1a receptor antagonist, in healthy volunteers

enthalten in: Expert opinion on investigational drugs | 2021

von Derks, M. | Lennon-Chrimes, S. | Guenther, A. | +5

7

Basmisanil, a highly selective GABAA-α5 negative allosteric modulator : preclinical pharmacology and demonstration of functional target engagement in man

enthalten in: Scientific reports | 2021

von Hipp, J. | Knoflach, F. | Comley, R. | +17

8

Bioavailability and pharmacokinetic profile of balovaptan, a selective, brain-penetrant vasopressin 1a receptor antagonist, in healthy volunteers

enthalten in: Expert opinion on investigational drugs | 2021

von Derks, M. | Lennon-Chrimes, S. | Guenther, A. | +5

9

Open-Label Assessment of the Effects of Itraconazole and Rifampicin on Balovaptan Pharmacokinetics in Healthy Volunteers

enthalten in: Advances in therapy | 2020

von Derks, M. | Wandel, C. | Young, A. | +2

10

PKPD and cardiac single cell modeling of a DDI study with a CYP3A4 substrate and itraconazole to quantify the effects on QT interval duration

enthalten in: Journal of pharmacokinetics and pharmacodynamics | 2020

von Jaminion, F. | Bentley, D. | Wang, K. | +3

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