Suchergebnisse - "Curtin, Nicola"

PubPharm (41)

1

Poly(ADP-ribose) polymerase inhibition : past, present and future

enthalten in: Nature reviews. Drug discovery | 2020

von Curtin, N. | Szabo, C.

2

Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors

enthalten in: Biochemical pharmacology | 2019

von Mukhopadhyay, A. | Drew, Y. | Matheson, E. | +4

3

Targeting the DNA Damage Response for Anti-Cancer Therapy

Erschienen: Cham, Springer International Publishing, 2018

Cancer Drug Discovery and Development

von Pollard, J. | Curtin, N.

4

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers

enthalten in: Cancer discovery | 2017

von de Bono, J. | Ramanathan, R. | Mina, L. | +13

5

Ovarian Cancers Harbor Defects in Nonhomologous End Joining Resulting in Resistance to Rucaparib

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2017

von McCormick, A. | Donoghue, P. | Dixon, M. | +6

6

Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity

enthalten in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society | 2016

von O'Donnell, R. | Kaufmann, A. | Woodhouse, L. | +4

7

Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis : Mechanism and Potential Role for PARP Inhibitors

enthalten in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society | 2016

von Kotsopoulos, I. | Kucukmetin, A. | Mukhopadhyay, A. | +2

8

PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia

enthalten in: Oncotarget | 2015

von Herriott, A. | Tudhope, S. | Junge, G. | +13

9

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

enthalten in: Oncotarget | 2015

von Middleton, F. | Patterson, M. | Elstob, C. | +9

10

Development of pharmacodynamic biomarkers for ATR inhibitors

enthalten in: Molecular oncology | 2015

von Chen, T. | Middleton, F. | Falcon, S. | +3

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